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1por Chauhan, Veeren M., Scurr, David J., Christie, Thomas, Telford, Gary, Aylott, Jonathan W., Pritchard, David I.“…Necator americanus, a haematophagous hookworm parasite, infects ~10% of the world’s population and is considered to be a significant public health risk. …”
Publicado 2017
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2por Tang, Yat T., Gao, Xin, Rosa, Bruce A., Abubucker, Sahar, Hallsworth-Pepin, Kymberlie, Martin, John, Tyagi, Rahul, Heizer, Esley, Zhang, Xu, Bhonagiri-Palsikar, Veena, Minx, Patrick, Warren, Wesley C., Wang, Qi, Zhan, Bin, Hotez, Peter J., Sternberg, Paul W., Dougall, Annette, Gaze, Soraya Torres, Mulvenna, Jason, Sotillo, Javier, Ranganathan, Shoba, Rabelo, Elida M., Wilson, Richard W., Felgner, Philip L., Bethony, Jeffrey, Hawdon, John M., Gasser, Robin B., Loukas, Alex, Mitreva, Makedonka“…The hookworm Necator americanus is the predominant soil-transmitted human parasite. …”
Publicado 2014
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4por Cantacessi, Cinzia, Mitreva, Makedonka, Jex, Aaron R., Young, Neil D., Campbell, Bronwyn E., Hall, Ross S., Doyle, Maria A., Ralph, Stuart A., Rabelo, Elida M., Ranganathan, Shoba, Sternberg, Paul W., Loukas, Alex, Gasser, Robin B.“…BACKGROUND: The blood-feeding hookworm Necator americanus infects hundreds of millions of people worldwide. …”
Publicado 2010
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5por GEIGER, S M, CALDAS, I R, MC GLONE, B E, CAMPI-AZEVEDO, A C, DE OLIVEIRA, L M, BROOKER, S, DIEMERT, D, CORRÊA-OLIVEIRA, R, BETHONY, J M“…We describe how hookworms interact with their human hosts by comparing lymphocyte phenotyping, proliferative responses, and cytokine and chemokine secretion patterns in adults who are either mono-infected with Necator americanus or egg-negative controls resident in an area of high transmission in Brazil. …”
Publicado 2007
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6por Hyun, Hee Jae, Kim, Eun-Min, Park, So Yeon, Jung, Jun-Oh, Chai, Jong-Yil, Hong, Sung-Tae“…Endoscopy isolated seven of them, which were identified as Necator americanus by characteristic morphology of cutting plates in the buccal cavity. …”
Publicado 2010
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7por Logan, Jayden, Pearson, Mark S., Manda, Srikanth S., Choi, Young-Jun, Field, Matthew, Eichenberger, Ramon M., Mulvenna, Jason, Nagaraj, Shivashankar H., Fujiwara, Ricardo T., Gazzinelli-Guimaraes, Pedro, Bueno, Lilian, Mati, Vitor, Bethony, Jeffrey M., Mitreva, Makedonka, Sotillo, Javier, Loukas, Alex“…The human hookworm Necator americanus infects more than 400 million people worldwide, contributing substantially to the poverty in these regions. …”
Publicado 2020
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8por Chapman, Paul R., Llewellyn, Stacey, Jennings, Helen, Becker, Luke, Giacomin, Paul, McDougall, Rodney, Robson, Jennifer, Loukas, Alex, McCarthy, James“…In this report, we detail the production and characterisation of Necator americanus larvae for use in a recently published clinical trial. …”
Publicado 2022
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9por Liu, Yumei, Liu, Hongxuan, Xie, Yuefeng, Zhang, Baohuan, Zou, Xiaoqian, Ou, Meiling, Ye, Xiaohong, Han, Yajing, Wu, Jing, Chen, Xiaojing, Dong, Shirui, Zhu, Kehui, Guo, Congcong, Wang, Penghua, Zhai, Hening, Jing, Chunxia, Yang, Guang“…RESULTS: In total, 64.12% of the parasite genome sequence was mapped to Necator americanus. fa, and 125,553 SNPs were detected. …”
Publicado 2019
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10por Ducarmon, Q. R., Hoogerwerf, M. A., Janse, J. J., Geelen, A. R., Koopman, J. P. R., Zwittink, R. D., Goeman, J. J., Kuijper, E. J., Roestenberg, M.“…Volunteers were dermally exposed to cumulative dosages of 50, 100 or 150 L3 Necator americanus larvae. Fecal samples were collected for microbiota profiling through 16S rRNA gene amplicon sequencing at weeks zero, four, eight, fourteen and twenty. …”
Publicado 2020
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11por Amoani, Benjamin, Adu, Bright, Frempong, Margaret T., Sarkodie-Addo, Tracy, Victor Nuvor, Samuel, Abu, Emmanuel Kwasi, Harrison, Lisa M., Cappello, Michael, Gyan, Ben, Wilson, Michael D.“…BACKGROUND: Necator americanus (hookworm) and Plasmodium falciparum co-infections are common in endemic communities in rural Ghana. …”
Publicado 2019
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12por Kwofie, Samuel K., Asiedu, Seth O., Koranteng, Russell, Quarshie, Emelia, Tiburu, Elvis K., Miller, Whelton A., Adinortey, Michael B., Wilson, Michael D.“…There are however concerns of low efficacy and drug resistance due to their repeated and excessive use. Although, Necator americanus glutathione S-transferase 3 (Na-GST-3) is a notable target, using natural product libraries for computational elucidation of promising leads is underexploited. …”
Publicado 2022
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13por Phosuk, Issarapong, Intapan, Pewpan M., Thanchomnang, Tongjit, Sanpool, Oranuch, Janwan, Penchom, Laummaunwai, Porntip, Aamnart, Witthaya, Morakote, Nimit, Maleewong, Wanchai“…The 2 principal species of hookworms infecting humans are Necator americanus and Ancylostoma duodenale. Case studies on zoonotic hookworm infections with Ancylostoma ceylanicum and/or Ancylostoma caninum are known mainly from Asian countries. …”
Publicado 2013
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14por Chang, Taehee, Jung, Bong-Kwang, Sohn, Woon-Mok, Hong, Sooji, Shin, Hyejoo, Ryoo, Seungwan, Lee, Jeonggyu, Lee, Keon Hoon, Khieu, Virak, Huy, Rekol, Chai, Jong-Yil“…Human hookworm infections caused by adult Ancylostoma spp. and Necator americanus are one of the most important tropical diseases. …”
Publicado 2020
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15por Rashwan, Nour, Bourguinat, Catherine, Keller, Kathy, Gunawardena, Nipul Kithsiri, de Silva, Nilanthi, Prichard, Roger“…METHODS: To address this problem, single nucleotide polymorphism (SNP) detection assays were developed based on the Smart amplification method (SmartAmp2) to target codons 167, 198, and 200 in the β-tubulin isotype 1 gene for the hookworm Necator americanus. FINDINGS: Diagnostic assays were developed and applied to analyze hookworm samples by both SmartAmp2 and conventional sequencing methods and the results showed high concordance. …”
Publicado 2016
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16por Wardell, Rebecca, Clements, Archie C. A., Lal, Aparna, Summers, David, Llewellyn, Stacey, Campbell, Suzy J., McCarthy, James, Gray, Darren J., V. Nery, Susana“…Infection status was determined for Ascaris lumbricoides and Necator americanus using real-time quantitative polymerase chain reaction. …”
Publicado 2017
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17“…Herein, we describe a peculiar case of effusive-constrictive pericarditis in an 18-year-old boy with polyserositis and concomitant Necator americanus infection.…”
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18por Geiger, Stefan Michael, Alexander, Neal Douglas Edward, Fujiwara, Ricardo Toshio, Brooker, Simon, Cundill, Bonnie, Diemert, David Joseph, Correa-Oliveira, Rodrigo, Bethony, Jeffrey Michael“…BACKGROUND: Helminth co-infection in humans is common in tropical regions of the world where transmission of soil-transmitted helminths such as Ascaris lumbricoides, Trichuris trichiura, and the hookworms Necator americanus and Ancylostoma duodenale as well as other helminths such as Schistosoma mansoni often occur simultaneously. …”
Publicado 2011
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19por Fujiwara, Ricardo T., Cançado, Guilherme G. L., Freitas, Paula A., Santiago, Helton C., Massara, Cristiano Lara, Carvalho, Omar dos Santos, Corrêa-Oliveira, Rodrigo, Geiger, Stefan M., Bethony, Jeffrey“…Mature DCs (mDCs) from Necator americanus (Necator)–infected individuals showed an impaired differentiation process compared to the mDCs of non-infected individuals, as evidenced by the differential expression of CD11c and CD14. …”
Publicado 2009
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20por Vaz Nery, Susana, Qi, Jessica, Llewellyn, Stacey, Clarke, Naomi E., Traub, Rebecca, Gray, Darren J., Vallely, Andrew J., Williams, Gail M., Andrews, Ross M., McCarthy, James S., Clements, Archie C. A.“…BACKGROUND: Soil-transmitted helminths (STHs) including Ascaris lumbricoides, Necator americanus, Ancylostoma spp. and Trichuris trichiura are cause of significant global morbidity. …”
Publicado 2018
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