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861por Lal, V“…This has been explained through an analogy between neglected tropical diseases (NTDs) and spatial neglect. The electronic databases such as MEDLINE, Tropical Diseases Research Division at the WHO and Google Scholar were consulted and reference lists of articles were searched for relevant material. …”
Publicado 2013
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862por Sekhon, B. S.“…Boron-based drugs, the benzoxaboroles have been exploited as potential treatments for neglected tropical diseases. Arsenic has been used as a medicinal agent and arsphenamine was the main drug used to treat syphilis. …”
Publicado 2013
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863por Kaiser, Marcel, Mäser, Pascal, Tadoori, Leela Pavan, Ioset, Jean-Robert, Brun, Reto“…Neglected tropical diseases cause significant morbidity and mortality and are a source of poverty in endemic countries. …”
Publicado 2015
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864“…It is meant to give a unified overview of these results in order to avoid repetitions caused, e.g., by limited access to some primary reports, and to stimulate further research to possibly facilitate the development of new molecular leads against protozoal neglected tropical diseases (NTDs) based on Salvia constituents.…”
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865por Grote, Alexandra, Caffrey, Conor R., Rebello, Karina M., Smith, David, Dalton, John P., Lustigman, Sara“…Neglected tropical diseases caused by metazoan parasites are major public health concerns, and therefore, new methods for their control and elimination are needed. …”
Publicado 2018
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866por Herrera Acevedo, Chonny, Scotti, Luciana, Feitosa Alves, Mateus, Formiga Melo Diniz, Margareth De Fátima, Scotti, Marcus Tullius“…This review presents an survey to the biological importance of sesquiterpene lactones (SLs) in the fight against four infectious neglected tropical diseases (NTDs)—leishmaniasis, schistosomiasis, Chagas disease, and sleeping sickness—as alternatives to the current chemotherapies that display several problems such as low effectiveness, resistance, and high toxicity. …”
Publicado 2017
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867“…Besides the therapeutic issue, the diagnosis of most neglected tropical diseases (NTD) is challenging. Confirmation using direct microscopy and culture, recognized as WHO essential diagnostic tests, are limited to specialized facilities. …”
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868por Jain, Sona, Santana, Wanessa, Dolabella, Silvio S., Santos, André L. S., Souto, Eliana B., Severino, Patrícia“…Leishmaniasis is one of the deadliest neglected tropical diseases affecting 12–15 million people worldwide, especially in middle- and low-income countries. …”
Publicado 2021
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869por Zhang, Zhen, Ray, Sneha, Imlay, Leah, Callaghan, Lauren T., Niederstrasser, Hanspeter, Mallipeddi, Prema Latha, Posner, Bruce A., Wetzel, Dawn M., Phillips, Margaret A., Smith, Myles W.“…Scalable access to spiroindimicins A, H, and their congeners has enabled discovery of their activity against several parasites relevant to human health, providing potential starting points for new therapeutics for the neglected tropical diseases leishmaniasis and African sleeping sickness.…”
Publicado 2021
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870por Rosa, Fernanda Andreia, Mendes de Souza Melo, Samara, Pianoski, Karlos Eduardo, Poletto, Julia, dos Santos, Mariellen Guilherme, Vieira da Silva, Michael Jackson, Lazarin‐Bidóia, Danielle, Volpato, Hélito, Moura, Sidnei, Nakamura, Celso Vataru“…A series of 60 4‐aminomethyl 5‐aryl‐3‐substituted isoxazoles were synthesized by an efficient method and evaluated in vitro against Leishmania amazonensis and Trypanosoma cruzi, protozoa that cause the neglected tropical diseases leishmaniasis and Chagas disease, respectively. …”
Publicado 2021
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871por Carbonell, Cristina, Rodríguez-Alonso, Beatriz, López-Bernús, Amparo, Almeida, Hugo, Galindo-Pérez, Inmaculada, Velasco-Tirado, Virginia, Marcos, Miguel, Pardo-Lledías, Javier, Belhassen-García, Moncef“…Schistosomiasis is a helminthic infection and one of the neglected tropical diseases (NTDs). It is caused by blood flukes of the genus Schistosoma. …”
Publicado 2021
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872por Durão, Raquel, Ramalhete, Cátia, Madureira, Ana Margarida, Mendes, Eduarda, Duarte, Noélia“…Human African trypanosomiasis (sleeping sickness) and American trypanosomiasis (Chagas disease) are vector-borne neglected tropical diseases, caused by the protozoan parasites Trypanosoma brucei and Trypanosoma cruzi, respectively. …”
Publicado 2022
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873por Oswald, William E, Kepha, Stella, Halliday, Katherine E, Mcharo, Carlos, Safari, Th'uva, Witek-McManus, Stefan, Hardwick, Robert J, Allen, Elizabeth, Matendechero, Sultani H, Brooker, Simon J, Njenga, Sammy M, Mwandawiro, Charles S, Anderson, Roy M, Pullan, Rachel L“…BACKGROUND: Few studies have been done of patterns of treatment during mass drug administration (MDA) to control neglected tropical diseases. We used routinely collected individual-level treatment records that had been collated for the Tuangamize Minyoo Kenya Imarisha Afya (Swahili for Eradicate Worms in Kenya for Better Health [TUMIKIA]) trial, done in coastal Kenya from 2015 to 2017. …”
Publicado 2020
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874por Chan, YuYen L., Patterson, Catriona L., Priest, Jeffrey W., Stresman, Gillian, William, Timothy, Chua, Tock H., Tetteh, Kevin, Lammie, Patrick, Drakeley, Chris, Fornace, Kimberly M.“…Current epidemiological trends of several neglected tropical diseases in these populations are at present absent due to the lack of habitual and efficient surveillance. …”
Publicado 2022
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875por Saayman, Maryna, Kannigadu, Christina, Aucamp, Janine, Janse van Rensburg, Helena D., Joseph, Cassiem, Swarts, Andrew J., N'Da, David D.“…Chagas disease and leishmaniasis are vector-borne infectious diseases affecting both humans and animals. These neglected tropical diseases can be fatal if not treated. Hundreds to thousands of new Chagas disease and leishmaniasis cases are being reported by the WHO every year, and currently available treatments are insufficient. …”
Publicado 2023
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876por Boutayeb, Abdesslam“…It is now commonly admitted that the so-called (most) neglected tropical diseases have been given little attention. …”
Publicado 2007
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877“…Leishmania species are the causative agents of the leishmaniases, a spectrum of neglected tropical diseases. Amastigote stage parasites exist within macrophages and scavenge host factors for survival, for example, Leishmania species utilise host sphingolipid for synthesis of complex sphingolipid. …”
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878“…Leishmaniasis ranks the third in disease burden in disability-adjusted life years caused by neglected tropical diseases and is the second cause of parasite-related deaths after malaria; but for a variety of reasons, it is not receiving the attention that would be justified seeing its importance. …”
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879“…In addition, hospitalizations and associated charges related to cysticercosis far exceeded those for malaria and were greater than for those for all other neglected tropical diseases combined. Neurocysticercosis is an increasing public health concern in the United States, especially among Hispanics, and costs the US health care system a substantial amount of money.…”
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880por Rojas-Caraballo, Jose, López-Abán, Julio, Fernández-Soto, Pedro, Vicente, Belén, Collía, Francisco, Muro, Antonio“…Fasciolosis is listed as one of the most important neglected tropical diseases according with the World Health Organization and is also considered as a reemerging disease in the human beings. …”
Publicado 2015
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