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  1. 1161
    “…A vast majority of the burden from neglected tropical diseases result from helminth infections (nematodes and platyhelminthes). …”
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    HelmCoP: An Online Resource for Helminth Functional Genomics and Drug and Vaccine Targets Prioritization
  2. 1162
    “…Identifying compounds that have already been developed to treat neglected tropical diseases is an attractive way to obtain lead compounds inexpensively that can be developed into much needed drugs, especially for use in developing countries. …”
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    Using Existing Drugs as Leads for Broad Spectrum Anthelmintics Targeting Protein Kinases
  3. 1163
    “…Trypanosomatid parasites are the causative agents of many neglected tropical diseases and there is currently considerable interest in targeting endogenous sterol biosynthesis in these organisms as a route to the development of novel anti-infective drugs. …”
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    Squalene Synthase As a Target for Chagas Disease Therapeutics
  4. 1164
    “…Lymphatic filariasis is one of several neglected tropical diseases with severely disabling and stigmatizing manifestations that are referred to as ‘neglected diseases of poverty’. …”
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    COMMUNITY MEMBERS' PERCEPTIONS OF MASS DRUG ADMINISTRATION FOR CONTROL OF LYMPHATIC FILARIASIS IN RURAL AND URBAN TANZANIA
  5. 1165
    “…Understanding the complex population biology and transmission ecology of multihost parasites has been declared as one of the major challenges of biomedical sciences for the 21st century and the Neglected Zoonotic Diseases (NZDs) are perhaps the most neglected of all the Neglected Tropical Diseases (NTDs). Here we consider how multihost parasite transmission and evolutionary dynamics may affect the success of human and animal disease control programmes, particularly neglected diseases of the developing world. …”
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    One health – an ecological and evolutionary framework for tackling Neglected Zoonotic Diseases
  6. 1166
    “…Chagas disease is one of the prevalent neglected tropical diseases, affecting at least 6–7 million individuals in Latin America. …”
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    Interactions between Trypanosoma cruzi Secreted Proteins and Host Cell Signaling Pathways
  7. 1167
    “…Schistosomiasis and trichuriasis are two of the most common neglected tropical diseases (NTD) that affect almost a billion people worldwide. …”
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    Identification of lead chemotherapeutic agents from medicinal plants against blood flukes and whipworms
  8. 1168
    por Zamanian, Mostafa, Andersen, Erik C.
    Publicado 2016
    “…Neglected tropical diseases caused by parasitic nematodes inflict an immense health and socioeconomic burden throughout much of the developing world. …”
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    Prospects and challenges of CRISPR/Cas genome editing for the study and control of neglected vector‐borne nematode diseases
  9. 1169
    “…It is also considered among the neglected tropical diseases. Diagnosis relies mainly on microscopy-based methods which are laborious, are limited by low sensitivity, and require high expertise. …”
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    Development of a Loop Mediated Isothermal Amplification for Diagnosis of Ascaris lumbricoides in Fecal Samples
  10. 1170
    por Pallangyo, Pedro, Nicholaus, Paulina
    Publicado 2016
    “…BACKGROUND: Tungiasis is one of the neglected tropical diseases; it affects up to 40% of individuals living in societies with poor housing and sanitation standards. …”
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    Disseminated tungiasis in a 78-year-old woman from Tanzania: a case report
  11. 1171
    “…Lymphatic filariasis and onchocerciasis are two important neglected tropical diseases (NTDs) that cause severe disability. …”
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    Identification and prioritization of novel anti-Wolbachia chemotypes from screening a 10,000-compound diversity library
  12. 1172
    “…BACKGROUND: Cutaneous leishmaniasis (CL) is one of the most important neglected tropical diseases and a major public health challenge in Iran caused by Leishmania spp and transmitted by phlebotomine sand flies. …”
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    Molecular Identification of Leishmania Species in a Re-Emerged Focus of Cutaneous Leishmaniasis in Varamin District, Iran
  13. 1173
    “…By unravelling how ABQs mediate their activities, features that facilitate the desired anti‐parasitic growth inhibitory effects could be incorporated into new, safer compounds targeting these neglected tropical diseases.…”
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    Distinct activation mechanisms trigger the trypanocidal activity of DNA damaging prodrugs
  14. 1174
    por Ghorbani, Masoud, Farhoudi, Ramin
    Publicado 2017
    “…Leishmaniasis has been reported as one of the most dangerous neglected tropical diseases, second only to malaria in parasitic causes of death. …”
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    Leishmaniasis in humans: drug or vaccine therapy?
  15. 1175
    “…Taxonomic identification and distribution studies of sand flies are important to understand the epidemiology and to control these neglected tropical diseases. RESULTS: Here, we identified more than 13,000 Lutzomyia specimens captured in Isla del Tigre, Honduras, through a classical morphological approach. …”
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    Bionomic aspects of Lutzomyia evansi and Lutzomyia longipalpis, proven vectors of Leishmania infantum in an endemic area of non-ulcerative cutaneous leishmaniasis in Honduras
  16. 1176
    “…Some nematode species are economically important parasites of livestock, while others are important human pathogens causing some of the most important neglected tropical diseases. In both humans and animals, anthelmintic drug administration is the main control strategy, but the emergence of drug-resistant worms has stimulated the development of alternative control approaches. …”
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    Transcriptomic profiling of nematode parasites surviving vaccine exposure
  17. 1177
    “…We hope that this initiative, coupled with the promising new hits we have reported, will lead to progress in drug discovery for this most neglected of neglected tropical diseases.…”
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    Addressing the most neglected diseases through an open research model: The discovery of fenarimols as novel drug candidates for eumycetoma
  18. 1178
    “…Neglected tropical diseases (NTDs) affect over one billion people all over the world. …”
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    Phenolic Constituents of Medicinal Plants with Activity against Trypanosoma brucei
  19. 1179
    “…BACKGROUND: Lassa fever is one of the most lethal neglected tropical diseases in West Africa. It is a serious public health problem in this region of Africa where it is endemic in several countries. …”
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    Report of a fatal case of Lassa fever in Parakou in 2018: clinical, therapeutic and diagnostic aspects
  20. 1180
    “…Trachoma and Guinea Worm Disease (GWD) are neglected tropical diseases (NTD) slated for elimination as a public health problem and eradication respectively by the World Health Organization. …”
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    Achieving the endgame: Integrated NTD case searches
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