“…Future work should assess its activity against hookworms and other pathogens that cause neglected tropical diseases.…”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Our findings are likely to extend beyond trachoma and should be considered when modelling other neglected tropical diseases.…”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The onchocerciasis transmission models EPIONCHO and ONCHOSIM have been independently developed and used to explore the feasibility of eliminating onchocerciasis from Africa with mass (annual or biannual) distribution of ivermectin within the timeframes proposed by the World Health Organization (WHO) and endorsed by the 2012 London Declaration on Neglected Tropical Diseases (i.e. by 2020/2025). Based on the findings of our previous model comparison, we implemented technical refinements and tested the projections of EPIONCHO and ONCHOSIM against long-term epidemiological data from two West African transmission foci in Mali and Senegal where the observed prevalence of infection was brought to zero circa 2007–2009 after 15–17 years of mass ivermectin treatment. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Schistosomiasis is a Neglected Tropical Diseases which can be prevented with mass deworming chemotherapy. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…BACKGROUND: Schistosoma mansoni is a trematode parasite that causes schistosomiasis, one of the most prevalent neglected tropical diseases, leading to the loss of 2.6 million disability-adjusted life years. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…BACKGROUND: Helminth infections are among the most prevalent neglected tropical diseases, causing an enormous impact in global health and the socioeconomic growth of developing countries. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Interventions for Reproductive, Maternal, Newborn and Child Health accounted for 37% of interventions, and major infectious diseases (AIDS, TB, malaria and neglected tropical diseases) for 24%, consistent with the priorities of the Millennium Development Goals. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…RESULTS: A total of 46 studies were included following full-text review of which 36 addressed non-communicable diseases and conditions, 7 addressed infectious diseases and 3 addressed neglected tropical diseases. Among ICF Activity and Participation Restrictions, work and employment was the highest reported category (19 studies), followed by intimate relationships (14 studies), and looking after one's health (8 studies). …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…BACKGROUND: Cutaneous Leishmaniasis (CL) which is prevalent in all continents and is classified by the WHO as one of the neglected tropical diseases, existed in the past also, and discovered ancient works confirm this issue. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Three‐dimensional structures of cytosolic DHODH of parasitic protozoa are of interest in drug discovery for neglected tropical diseases, especially because these enzymes possess significantly different structural and functional properties from the membrane‐associated human enzyme. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Four of the six PLOS journals, Genetics, Pathogens, Computational Biology, and Neglected Tropical Diseases, show significant positive correlations across all datasets. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Flubendazole (a benzimidazole) has been reformulated by Janssen Pharmaceutica as an amorphous solid drug nanodispersion to develop an orally bioavailable medicine for the treatment of neglected tropical diseases such as onchocerciasis. We investigated the in vitro activity, the structure-activity-relationships, and both in vitro and in vivo pharmacodynamics of flubendazole for cryptococcal meningitis. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…BACKGROUND: Strongyloides stercoralis is one of the most neglected tropical diseases. Sparse, dated central African and Rwandan data on seroprevalence are available to guide public health efforts and clinical care. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…BACKGROUND: Scabies was added to the WHO Neglected Tropical Diseases portfolio in 2017, and further understanding of the disease burden is now required. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Among 868 reported zoonoses, echinococcosis (hydatid disease) is one of the most severe public health problems and listed as one of 17 neglected tropical diseases targeted for control by the World Health Organization. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…BACKGROUND: Lymphatic filariasis (LF) and podoconiosis are neglected tropical diseases (NTDs) that pose a significant physical, social and economic burden to endemic communities. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Water, sanitation and hygiene (WASH) programmes are included among the key strategies for achieving the World Health Organization’s 2020 Roadmap for Implementation for control of Neglected Tropical Diseases (NTDs). There exists a lack of knowledge regarding the effect of animals on the effectiveness of WASH measures. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Neglected tropical diseases, especially those caused by parasites, are significantly underserved by current drug development efforts, mostly due to the high costs and low economic returns. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Considerable progress has been made in the establishment of policies for the achievement of the Millennium Development Goals (MDGs), later followed by the Sustainable Development Goals (SDGs) through WHO-lead actions for the control of neglected tropical diseases (NTDs). With an initial goal of morbidity control, there are already discussions and proposals for elimination of STH if support is sustained and empiric facts confirm data emerging from modeling and small-scale studies. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…It is one of the neglected tropical diseases identified by the World Health Organization for elimination as a public health problem by 2020. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso