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  1. 288241
    “…METHODS: Data were collected by archiving all public comments made in response to a news study about a school-based ATOD survey that was featured on a common social networking platform. Using the general inductive approach and elements of thematic analysis, two researchers followed a multi-step protocol to clean, categorize, and consolidate data, generating codes for all 207 responses. …”
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    Social Media Outrage in Response to a School-Based Substance Use Survey: Qualitative Analysis
  2. 288242
    “…It is regulated in coordination with other events in RNA metabolism such as transcription, polyadenylation, RNA transport, and nonsense-mediated decay via protein networks. SERINE/ARGININE-RICH 45 (SR45) is thought to be a neutral splicing regulator. …”
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    Quantitative Proteomics Reveals a Role for SERINE/ARGININE-Rich 45 in Regulating RNA Metabolism and Modulating Transcriptional Suppression via the ASAP Complex in Arabidopsis thaliana
  3. 288243
    “…Consistent with impaired mitochondrial fusion, mitochondrial networks in fibroblasts were found to be fragmented. …”
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    MSTO1 mutations cause mtDNA depletion, manifesting as muscular dystrophy with cerebellar involvement
  4. 288244
    “…Outcomes, measured at baseline, and post-intervention (at 22 weeks post-baseline and 52 weeks post-baseline) included daily minutes of moderate to vigorous physical activity (MVPA) (measured using ActiGraph accelerometer), mental wellbeing (Warwick-Edinburgh Mental Wellbeing Scale), social support for physical activity, time preference (for delayed and larger rewards or immediate and smaller rewards), pro-social behaviour (Strengths and Difficulties Questionnaire (SDQ)) and the influence of social networks. The intervention’s acceptability was explored in focus groups. …”
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    A feasibility study of ‘The StepSmart Challenge’ to promote physical activity in adolescents
  5. 288245
    “…Connectivity metrics included fractional amplitude of low-frequency fluctuations (fALFF) and regional homogeneity (ReHo) of both motor cortices, strength of related brain networks, and inter-hemispheric connectivity. The group-analysis revealed few trends (i.e., uncorrected for multiple comparisons), including a mean increase in the concentration of the inhibitory neurotransmitter γ-aminobutyric acid (GABA) after the inhibitory rTMS protocol as compared to baseline in the stimulated (left) motor cortex (+8%, p = 0.043), along with a slight increase of total creatine (+2%, p = 0.018), and decrease of aspartate (−18%, p = 0.016). …”
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    Influence of Repetitive Transcranial Magnetic Stimulation on Human Neurochemistry and Functional Connectivity: A Pilot MRI/MRS Study at 7 T
  6. 288246
    por van Santen, Jeffrey A., Jacob, Grégoire, Singh, Amrit Leen, Aniebok, Victor, Balunas, Marcy J., Bunsko, Derek, Neto, Fausto Carnevale, Castaño-Espriu, Laia, Chang, Chen, Clark, Trevor N., Cleary Little, Jessica L., Delgadillo, David A., Dorrestein, Pieter C., Duncan, Katherine R., Egan, Joseph M., Galey, Melissa M., Haeckl, F.P. Jake, Hua, Alex, Hughes, Alison H., Iskakova, Dasha, Khadilkar, Aswad, Lee, Jung-Ho, Lee, Sanghoon, LeGrow, Nicole, Liu, Dennis Y., Macho, Jocelyn M., McCaughey, Catherine S., Medema, Marnix H., Neupane, Ram P., O’Donnell, Timothy J., Paula, Jasmine S., Sanchez, Laura M., Shaikh, Anam F., Soldatou, Sylvia, Terlouw, Barbara R., Tran, Tuan Anh, Valentine, Mercia, van der Hooft, Justin J. J., Vo, Duy A., Wang, Mingxun, Wilson, Darryl, Zink, Katherine E., Linington, Roger G.
    Publicado 2019
    “…The Natural Products Atlas has been developed under FAIR principles (Findable, Accessible, Interoperable, and Reusable) and is integrated with other emerging natural product databases, including the Minimum Information About a Biosynthetic Gene Cluster (MIBiG) repository, and the Global Natural Products Social Molecular Networking (GNPS) platform. It is designed as a community-supported resource to provide a central repository for known natural product structures from microorganisms and is the first comprehensive, open access resource of this type. …”
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    The Natural Products Atlas: An Open Access Knowledge Base for Microbial Natural Products Discovery
  7. 288247
    “…Moreover, Integrated Pathway Analysis (IPA) in serum revealed activation of five major anabolic metabolic networks contributing to proliferation and growth. …”
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    Metabolic consequences of perioperative oral carbohydrates in breast cancer patients — an explorative study
  8. 288248
    “…Social media, online forums, and meeting in person were ranked the most preferable methods for communication with support groups networks and charities. Most respondents stated that they had a good understanding of research reports (71/80, 89%) and statistics (68/80, 85%) and could differentiate among the different types of research methodologies (62/80, 78%). …”
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    Exploring Research Priorities of Parents Who Have Children With Down Syndrome, Cleft Lip With or Without Cleft Palate, Congenital Heart Defects, or Spina Bifida Using ConnectEpeople: A Social Media Coproduction Research Study
  9. 288249
    “…According to TCR clonotype networks constructed by connecting all the CDR3 sequences with a Levenshtein distance of 1, 3 IgG4-RD-specific clusters were identified. …”
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    High-throughput sequencing of CD4(+) T cell repertoire reveals disease-specific signatures in IgG4-related disease
  10. 288250
    “…In China, WeChat, an instant messaging and social networking app released by the company Tencent, has developed a specific type of user account called WeChat official account (WOA), which is now widely adopted by hospitals in China. …”
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    Understanding the Function Constitution and Influence Factors on Communication for the WeChat Official Account of Top Tertiary Hospitals in China: Cross-Sectional Study
  11. 288251
    “…Since data related to the importance of HIF1 and 2 in hematopoietic stem and progenitors is conflicting, we investigated the chromatin binding profiles of HIF1 and HIF2 and linked that to transcriptional networks and the cellular metabolic state. METHODS: Genome-wide ChIPseq and ChIP-PCR experiments were performed to identify HIF1 and HIF2 binding sites in human acute myeloid leukemia (AML) cells and healthy CD34(+) hematopoietic stem/progenitor cells. …”
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    HIF1/2-exerted control over glycolytic gene expression is not functionally relevant for glycolysis in human leukemic stem/progenitor cells
  12. 288252
    “…This work aims to further elucidate the regulatory networks of SNHG1 involved in PD. METHODS: 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-hydrochloride (MPTP)-induced mice and 1-methyl-4-phenylpyridinium (MPP(+))-treated SH-SY5Y cells were respectively constructed as the in vivo and in vitro PD models. …”
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    SNHG1 promotes MPP(+)-induced cytotoxicity by regulating PTEN/AKT/mTOR signaling pathway in SH-SY5Y cells via sponging miR-153-3p
  13. 288253
    “…The sequences were used for determination of HIV subtypes and the presence of drug resistance mutations. Transmission networks were constructed to explore possible relationships. …”
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    Genetic characterization of HIV-1 epidemic in Anhui Province, China
  14. 288254
    “…Here we introduce a deep learning model that uses a set of cascaded convolutional neural networks (CNNs) to predict Cα atoms along a protein’s backbone structure. …”
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    Deep Learning to Predict Protein Backbone Structure from High-Resolution Cryo-EM Density Maps
  15. 288255
    “…CONCLUSION: Multimodal analysis conducted with various image data from PiB-PET/MRI scans showed differences in regional CBF, cortical volume, and neuronal networks in different regions, indicating that pathophysiologic and functional changes in the AD brain can be observed from various aspects of neurophysiologic parameters. …”
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    Multimodal analysis using [(11)C]PiB-PET/MRI for functional evaluation of patients with Alzheimer’s disease
  16. 288256
    “…Expressed by developing neural tissue (neuron and glia progenitors), they influence the formation of central nervous system (CNS) vascular networks. Another type of factors are tissue-specific paracrine factors produced by endothelial cells (ECs), also known as ‘angiocrine’ factors, that provide instructive signals to regulate homeostatic and regenerative processes. …”
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    Angiomodulin (IGFBP7) is a cerebral specific angiocrine factor, but is probably not a blood–brain barrier inducer
  17. 288257
    “…In setting 1, local social networks enabled intergenerational learning about sexual health and facilitated accompanied visits to health clinics for young women. …”
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    Young Aboriginal people’s engagement with STI testing in the Northern Territory, Australia
  18. 288258
    por Heymann, D.L., Reinhardt, K.
    Publicado 2014
    “…If the misunderstanding is transmitted widely by the press or through social media networks, the negative economic impact can be amplified. …”
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    Emerging Infections, the International Health Regulations, and Macro-Economy
  19. 288259
    “…BACKGROUND: Retirees face numerous challenges, including disassociation from persons in their social networks in Nigeria. Perceived social isolation or loneliness could impair the quality of life in old age, and lead to mental disorders. …”
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    Prevalence of loneliness and association with depressive and anxiety symptoms among retirees in Northcentral Nigeria: a cross-sectional study
  20. 288260
    “…Senescent cells are hypothesized to exhibit different upregulated pro-survival/anti-apoptotic networks depending on the senescent inducers. This might limit the effect of a particular senolytic compound that targets rather only a specific pathway. …”
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    Senolytic compounds control a distinct fate of androgen receptor agonist- and antagonist-induced cellular senescent LNCaP prostate cancer cells
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