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  1. 541
    por Washio, Masakazu, Mori, Mitsuru
    Publicado 2009
    “…Although the incidence of renal cell cancer in Japan is lower than the rates in the other industrialized countries, there is no doubt that it is increasing. In this paper, we would like to introduce the result of our studies, which evaluate the risk factors for renal cell cancer in Japan. …”
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    Risk Factors for Renal Cell Cancer in a Japanese Population
  2. 542
    por Sheikhattari, Payam, Kamangar, Farin
    Publicado 2010
    “…Health statistics leave little doubt that the current health system in Iran, which is mainly based on primary health care (PHC), is a functioning one, and that health in Iran has improved far beyond where it was 40 years ago. …”
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    How Can Primary Health Care System and Community-Based Participatory Research Be Complementary?
  3. 543
    por Brosens, Ivo, Benagiano, Giuseppe
    Publicado 2011
    “…There is, however, no doubt that Thomas Cullen was the first to describe endometriosis and adenomyosis as one disease characterized by the presence of endometrium-like tissue outside the uterine cavity. …”
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    Endometriosis, a modern syndrome
  4. 544
    por McCleery, Iona
    Publicado 2009
    “…Duarte's writings can be used to explore the impact of plague, doubt and death on the life of a well-educated and conscientious late-medieval ruler.…”
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    Both “illness and temptation of the enemy”: melancholy, the medieval patient and the writings of King Duarte of Portugal (r. 1433–38)
  5. 545
    “…The authors feel it is essential to understand the importance of ruling out a bone tumour, if the possibility has been raised, before managing a suspected fracture. If there is any doubt, the case should be referred to an appropriate sarcoma unit for review prior to any intervention.…”
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    Avulsion fracture of the anterior superior iliac spine: misdiagnosis of a bone tumour
  6. 546
    “…In particular, results of trials and further research into their use in heart failure, stress incontinence, and muscular dystrophies are eagerly awaited. Although no doubt, stem cells will have much to offer in the future, the results of further research still limit their use.…”
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    The Potential of Stem Cells in the Treatment of Skeletal Muscle Injury and Disease
  7. 547
    por Chica, Ana B., Bartolomeo, Paolo
    Publicado 2012
    “…Recent evidence of double dissociations between attention and consciousness cast doubt on the time-honored concept of attention as a gateway to consciousness. …”
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    Attentional Routes to Conscious Perception
  8. 548
    por Mukherjee, Shoibal
    Publicado 2012
    “…In implementing regulations for suo moto compensation, India is seeking to establish a practice not previously tested elsewhere in the world. There is no doubt that industry must support the idea of putting patients first, but procedural considerations in fixing causality and determining the quantum of compensation promise to raise questions of morality, ethics, and jurisprudence that will not be easy to answer.…”
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    Compensation conundrum
  9. 549
    “…Analogous to NADPH oxidase, role of NOS is proved beyond any doubt for killing of intracellular pathogen like Mycobacterium tuberculosis. …”
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    Glycation of calmodulin binding domain of iNOS may increase the chance of occurrence of tuberculosis in chronic diabetic state
  10. 550
    por Soni, Neil
    Publicado 2012
    “…Many clinicians have already moved to the lower molecular weight starches on the basis of doubt rather than certainty, but this study tips the balance. …”
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    Hydroxyethylstarch 200/0.5 - the horse has bolted
  11. 551
    “…These data confirm the poor evidence of PTH after a light trauma and lead to doubt of the existence of this nosological entity.…”
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    Post–traumatic headache from moderate head injury
  12. 552
    “…The findings from the review support the development of an LF-specific disability measurement tool and raise doubt about the suitability of generic disability tools to assess disability related to neglected tropical diseases (NTDs) globally.…”
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    Disability Measurement for Lymphatic Filariasis: A Review of Generic Tools Used within Morbidity Management Programs
  13. 553
    “…When a differential diagnosis of the intramedullary spinal cord lesion is in doubt, evaluation for eosinophilic myelitis and toxocariasis would be beneficial.…”
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    Eosinophilic Myelitis in the Cervical Cord Mimicking Intramedullary Cord Tumor
  14. 554
    “…The evolution of human blood groups, without doubt, has a history as old as man himself. There are at least three hypotheses about the emergence and mutation of human blood groups. …”
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    A Brief History of Human Blood Groups
  15. 555
    por Calverley, Peter MA
    Publicado 2013
    “…The reasons for this include a view that cough arises simply from the direct irritant and inflammatory effect of cigarette smoke or the presence of excess mucus in the airways. Doubt that cough is of any consequence to patients or responsive to current therapies has reinforced this opinion. …”
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    Cough in chronic obstructive pulmonary disease: is it important and what are the effects of treatment?
  16. 556
    “…Because the autoxidation of NO is second order in NO, it is extremely slow at submicromolar NO concentrations, casting doubt on its physiological relevance. In this paper we present evidence that at submicromolar NO concentrations the aerobic nitrosation of glutathione does not involve NO autoxidation but a reaction that is first order in NO. …”
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    Efficient nitrosation of glutathione by nitric oxide()
  17. 557
    por Boeckx, Cedric, Leivada, Evelina
    Publicado 2013
    “…The empirical issues uncovered cast doubt on classical parametric models of language acquisition as well as on the conceptualization of an overspecified Universal Grammar that has parameters among its primitives. …”
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    Entangled Parametric Hierarchies: Problems for an Overspecified Universal Grammar
  18. 558
    “…Radiologists and clinicians should be aware of this pitfall and should perform a biopsy in cases of doubt.…”
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    Displacement of Malignant Cells into the Portal Triad of the Liver Results in Reduced Liver Perfusion, Mimicking Segmental Fatty Liver
  19. 559
    “…Overall, this review summarizes the hepatoprotective activities in vitro and in vivo. However, there is no doubt that human and clinical trials are still limited, and further studies are required for the development of AC-related products.…”
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    Current evidence for the hepatoprotective activities of the medicinal mushroom Antrodia cinnamomea
  20. 560
    por Norata, Giuseppe Danilo
    Publicado 2012
    “…The key role of dyslipidaemia in determining cardiovascular disease (CVD) has been proved beyond reasonable doubt, and therefore several dietary and pharmacological approaches have been developed. …”
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    Established and Emerging Approaches for the Management of Dyslipidaemia
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