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  1. 741
    “…Nowadays, thanks to recent studies, we know many important functions of this, no doubt, interesting membraneless nucleus sub-organelle involved in oocyte maturation, embryonic genome activation, rRNA synthesis, etc. …”
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    Improving the Quality of Oocytes with the Help of Nucleolotransfer Therapy
  2. 742
    “…Global analysis based on the Eigen–Weller model is satisfactory in all solvents, but the marked mechanistic differences between aqueous and organic solvents cast doubt on the physical validity of the rate constants obtained.…”
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    Broadband fluorescence reveals mechanistic differences in excited-state proton transfer to protic and aprotic solvents
  3. 743
    “…The deposition and removal of fibrin has been the primary role of coagulation and fibrinolysis, respectively. There is also little doubt that these 2 enzyme cascades influence each other given they share the same serine protease family ancestry and changes to 1 arm of the hemostatic pathway would influence the other. …”
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    The Fibrinolytic System: Mysteries and Opportunities
  4. 744
    “…There is no doubt that many synthetic materials used in cranioplasty have given good result regarding patient's calvarial shape. …”
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    Customized Cost-Effective Polymethyl-Methacrylate Cranioplasty Implant Using Three-Dimensional Printer
  5. 745
    por Michaels, Jeffrey H.
    Publicado 2021
    “…This article argues that despite recently prioritizing China in its discourse, the historical record provides ample reasons to cast doubt on any expectations this will lead to major substantive changes in NATO’s diplomacy or military posture.…”
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    ‘A very different kind of challenge’? NATO’s prioritization of China in historical perspective
  6. 746
    “…Extensive research over 100 years has demonstrated that tumors can be eliminated by the autologous immune system. Without doubt, immunotherapy is now a standard treatment along with surgery, chemotherapy, and radiotherapy; however, the field of cancer immunotherapy is continuing to develop. …”
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    Fundamental and Essential Knowledge for Pathologists Engaged in the Research and Practice of Immune Checkpoint Inhibitor-Based Cancer Immunotherapy
  7. 747
    “…Obesity, low steroid hormone-binding globulin (SHBG), hyperandrogenemia, insulin resistance, and compensatory hyperinsulinemia are biomediators and early predictors of metabolic complications in PCOS. Doubts remain about the real risk of CV diseases in PCOS and the molecular mechanisms at the basis of CV complications. …”
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    Biomediators in Polycystic Ovary Syndrome and Cardiovascular Risk
  8. 748
    por Gaddy, Hampton Gray
    Publicado 2021
    “…Using higher-powered mortality data, I cast doubt on both findings by analyzing the experiences of the pandemic in 43 of the largest American cities of the time. …”
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    Social distancing and influenza mortality in 1918 did not increase suicide rates in the United States
  9. 749
    por Papatzikis, Efthymios
    Publicado 2021
    “…The reactions to this coronavirus pandemic have no doubt affected all aspects of our everyday normalcy as they have called for an extended set of measures that have greatly impacted our social interactions and well-being. …”
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    An Infant's Question on COVID-19 and Music: Should I Attend My Online Classes?
  10. 750
    “…Research in biomedical sciences has changed dramatically over the past fifty years. There is no doubt that the discovery of apoptosis and autophagy as two highly synchronized and regulated mechanisms in cellular homeostasis are among the most important discoveries in these decades. …”
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    Over Fifty Years of Life, Death, and Cannibalism: A Historical Recollection of Apoptosis and Autophagy
  11. 751
    por Vivion, Maryline, Gauvin, Lise
    Publicado 2022
    “…There is no longer any doubt that exposure to the tsunami of health information which is sometimes evidence-based and sometimes unfounded and even misleading, is a public health issue. …”
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    Integrating infoveillance, infodemiology, and consequential intervention research in our public health systems to better protect and promote the health of Canadians: ideas and perspectives
  12. 752
    “…There is no doubt that new technology has become one of the crucial parts of most people’s lives around the world. …”
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    A Comprehensive Survey on the Internet of Things with the Industrial Marketplace
  13. 753
    “…Messenger RNA (mRNA) technology finally showed and shared its potential, starting a new era in medicine. However, there is no doubt that commercialization of these vaccines would not have been possible without nanotechnology, which has finally answered the long-term question of how to deliver mRNA in vivo. …”
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    The Potential of Nanomedicine to Unlock the Limitless Applications of mRNA
  14. 754
    “…While they constitute a bulwark against widespread vaccine hesitancy, informative supports can be tainted by doubt if they are not backed up by solid arguments convincingly addressing the manifold questions and concerns of healthcare users.…”
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    Reprint of: Development of vaccines and vaccinal strategies against COVID-19: The information contributing to shared decision-making
  15. 755
    “…This article is a review of literature on the use of PRP in gynecology and obstetrics. There is no doubt that the released growth factors and proteins have a beneficial effect on wound healing and regeneration processes. …”
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    Platelet Rich Plasma in Gynecology—Discovering Undiscovered—Review
  16. 756
    “…Exosomes (30 to 100 nm) are a subset of EVs, and their importance in future medicine is beyond any doubt. However, the lack of efficient isolation and detection techniques hinders their practical applications as biomarkers. …”
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    Microfluidic Platforms for the Isolation and Detection of Exosomes: A Brief Review
  17. 757
    “…CONCLUSIONS: There is still insufficient evidence to validate the efficacy of some of these techniques, and further research is needed to consolidate these industrial production systems. There is no doubt that more strategies, systems, and pipelines will contribute to enhance biopharmaceutical production.…”
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    Expression of mammalian proteins for diagnostics and therapeutics: a review
  18. 758
    “…The need to address socio-cultural and religious standpoints on COVID-19 immunization and related discussions is becoming more pressing as the pandemic's socioeconomic implications become more concerning. Without a doubt, failing to address social issues jeopardizes countries' ability to achieve the WHO-recommended 70 percent coverage target for all countries, which would halt the pandemic by creating a global herd immunity. …”
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    Addressing the social issues around vaccination could be the pivotal strategy to achieve the 2022 COVID-19 vaccination coverage target
  19. 759
    por Jeon, Junhyun
    Publicado 2022
    “…A survey of research works published in the Plant Pathology Journal, however, cast doubt on high standard of statistical analysis required for scientific rigor and reproducibility in the journal. …”
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    A Brief Guide to Statistical Analysis and Presentation for the Plant Pathology Journal
  20. 760
    “…RESULTS: It was determined that the total score of the UTBAS scale, the high scores on the fear of negative evaluation, avoidance, self-doubt and insecurity, and the hopelessness subscales, and the low scores of the perceived social support scale were correlated with lower psychological well-being results in stuttering individuals. …”
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    Mental well-being and related factors in individuals with stuttering
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