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702661por Boutin, Catherine-Audrey, Callegari, Michelle A, Florescu, Diana F, Nguyen, Minh-Hong, Kaul, Daniel, Avery, Robin K, Chong, Pearlie P, Fisher, Cynthia E, Limaye, Ajit, Clough, Lisa A, Pergam, Steven A, Green, Michael D, Michaels, Marian G, Danziger-Isakov, Lara A, Angarone, Michael P, Keefer, Laurie, Daud, Amna, Ison, Michael“…Although NTZ appears safe, its role is likely limited in the setting of chronic NoV among ICHs. …”
Publicado 2023
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702662por Mendes, Rodrigo E, Kimbrough, John H, Kantro, Valerie, Shortridge, Dee, Sader, Helio S, Castanheira, Mariana“…CONCLUSION: CFDC activity against ENT was consistent, regardless of isolate phenotypes or genotypes, including against isolates carrying carbapenemase genes other than bla(KPC), where approved β-lactam/β-lactamase inhibitor combinations showed limited activity. These data emphasize CFDC as an important option for the treatment of infections caused by ENT and resistant subsets. …”
Publicado 2023
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702663por Landi, Suzanne, Garofalo, Diana, Soo, Chern Chuan, Scott, Amie, Jiang, Lili, McCarthy, Jill, Tawadrous, Margaret, Pixton, Glenn, Alami, Niki, Kelly, Scott P, Swan, Joshua T“…Understanding the risk of hospitalization after RSV diagnosis through current real-world data analyses is limited by estimates combining cases identified in inpatient and outpatient settings. …”
Publicado 2023
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702664“…BACKGROUND: The incidence of nontuberculous mycobacterial pulmonary disease (PNTM) is rising, but available diagnostics and treatments have limitations. The lung microbiota plays an important role in the onset and progression of lung diseases. …”
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702665por Scott, Amie, Puzniak, Laura A, Murphy, Michael V, Benjumea, Darrin W, Rava, Andrew, Benigno, Michael, Allen, Kristen E, Stanford, Richard, Manuel, Fadi, Cha-Silva, Ashley S, Jiang, Lili, Reimbaeva, Maya, Draica, Florin“…Death within 1 calendar month after hospitalization was used as a proxy for inpatient death, due to database limitations. Receipt of a COVID-19 outpatient therapeutic (Table 1) in the 30 days prior to hospital admission was assessed by death, age, number of high-risk conditions, and immunocompromised status. …”
Publicado 2023
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702666por de St. Maurice, Annabelle M, Qwaider, Yasmeen Z, Stopczynski, Tess, Williams, John V, Michaels, Marian G, Sahni, Leila C, Boom, Julie A, Spieker, Andrew J, Klein, Eileen J, Englund, Janet A, Staat, Mary A, Schlaudecker, Elizabeth P, Selvarangan, Rangaraj, Schuster, Jennifer E, Zhou, Yingtao, Moline, Heidi L, Szilagyi, Peter G, Halasa, Natasha B, Weinberg, Geoffrey A“…BACKGROUND: Human parainfluenza viruses (PIV) are a leading cause of pediatric acute respiratory infection (ARI), yet limited data exist on PIV-associated hospitalizations, particularly from serotype PIV-4, a serotype reported to cause severe disease. …”
Publicado 2023
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702667por DeJonge, Boudewijn L, Nguyen, Sean T, Bryowsky, Jason J, Longshaw, Christopher M, Maher, Joshua, Mendes, Rodrigo E, Takemura, Miki, Yamano, Yoshinori“…BACKGROUND: Difficult to Treat Resistant (DTR) Gram-negative isolates show treatment-limiting resistance to all first-line agents; β-lactams and fluoroquinolones. …”
Publicado 2023
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702668por Mughrabi, Abdallah, Maamari, Julian, Phillips, Timothy, Alabbasi, Afaq, Brooks, Aislinn, Nuriev, Rinat, Zenkin, Lisa, Jaber, Bertrand, Nader, Claudia“…When applicable, a narrower beta-lactam therapy such as ceftriaxone may be appropriate. Limitations include a small sample size, with higher risk for type II error, and overlap in definitive antibiotic therapy. …”
Publicado 2023
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702669por Mellis, Alexandra, Biddle, Jessica E, Antoon, James W, McLaren, Son H, Belongia, Edward, Maldonado, Yvonne A, Bowman, Natalie M, Ellingson, Katherine, Rao, Suchitra, Johnson, Sheroi, Stockwell, Melissa, Sano, Ellen, Silverio, Raul A, Bullock, Ayla, Yang, Amy, Haehnel, Quenla, McLean, Huong, Petrie, Joshua, Sarnquist, Clea, Govindaranjan, Prasanthi, Goodman, Sara H, Lutrick, Karen, Ledezma, Karla I, Pryor, Kathleen, Asturias, Edwin J, Zhu, Yuwei, Schmitz, Jonathan, Hart, Kimberly W, Grijalva, Carlos G, Talbot, H Keipp, Rolfes, Melissa A“…BACKGROUND: Oseltamivir is the most common antiviral prescribed to treat influenza. There are limited data about oseltamivir receipt in uncomplicated influenza, including frequency of early discontinuation of oseltamivir. …”
Publicado 2023
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702670por Soens, Mieke, Kandinov, Boris, Ramirez-Schrempp, Daniela, Vakil, Jignesh, Pucci, Alicia, Huang, Wenmei, Guo, Jia, Du, Evelyn, Avanesov, Andrei, Rudden, Sinead, Hicks, Bryony, Livermore, Greg, Schaefers, Kristi, Lau, Mary, Nachbagauer, Raffael, Ananworanich, Jintanat“…Vaccines based on messenger RNA (mRNA) technology are currently under investigation and have the potential to address limitations of current seasonal influenza vaccine platforms. …”
Publicado 2023
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702671por Lahiri, Cecile D, Dumond, Julie B, Christina Mehta, Cyra, Yang, Qian, Sheth, Anandi N, Ofotokun, Igho, Sykes, Craig, Hartauer, Mattie, Khoei, Adrian, Alcaide, Maria L L, Lake, Jordan, Rubin, Leah H, Konkle-Parker, Deborah, Adimora, Adaora A, Topper, Elizabeth F, French, Audrey L, Cocohoba, Jennifer, Kassaye, Seble, Augenbraun, Michael, Sharma, Anjali, Tien, Phyllis C“…In contrast, the effect of DTG and EVG plasma drug exposure on short-term body weight change appears to be limited. Mechanisms contributing to body weight gain may be INSTI-specific. …”
Publicado 2023
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702672“…BACKGROUND: Talaromyces marneffei (Tm) is a thermally dimorphic fungus causing invasive mycosis in human immunodeficiency virus (HIV) infected patients in Southeast Asia and is a leading cause of AIDS-related deaths in this region with mortality on anti-fungal therapy as high as 30%. The limited options, routes of administration, and toxicity of antifungals with established efficacy against Tm calls for assessment of efficacy for additional antifungals against Tm. …”
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702673por Ryu, Do-Yeal, Pang, Won-Ki, Adegoke, Elikanah Olusayo, Rahman, Md Saidur, Park, Yoo-Jin, Pang, Myung-Geol“…LARGE SCALE DATA: Not applicable. LIMITATIONS, REASONS FOR CAUTION: Since the protein expression levels in the testes were validated, in vitro studies in each testicular cell type (Leydig cells, Sertoli cells, and spermatogonial stem cells) would be required to shed further light on the exact mechanism resulting from BPA exposure. …”
Publicado 2023
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702674“…However, information on how ethanol affects MAPKs in the context of innate antiviral pathways such as the Jak-Stat pathway in human cells is extremely limited. When IFN-α binds its receptor, two receptor associated tyrosine kinases, Tyk2 and Jak1 become activated by phosphorylation, and phosphorylate Stat1 and Stat2 on conserved tyrosine residues [13]. …”
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702675“…No definite conclusions can be drawn from the last series of experiments. From this limited study it seems probable that lobar pneumonic processes are produced less easily after intravenous injection of various cocci and insufflation of irritating substances than by-similar treatment with Friedländer's bacillus.…”
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702676por Sabin, Albert B.“…As a result of this zone phenomenon, which, it is important to note, was not observed in the agglutination or mouse protection tests on the same fractions, the range of effective dosage is very narrowly limited. Although the results of agglutination tests correlated well with those of the mouse protection tests, both of these showed no parallelism with the therapeutic effects of the various fractions on the experimental, dermal, pneumococcus infection in rabbits.…”
Publicado 1933
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702677por Aragon-Martin, Jose A., Ritch, Robert, Liebmann, Jeffrey, O’Brien, Colm, Blaaow, Karima, Mercieca, Franco, Spiteri, Anthony, Cobb, Caroline J., Damji, Karim F., Tarkkanen, Ahti, Rezaie, Tayebeh, Child, Anne H., Sarfarazi, Mansoor“…However, the LOXL1 genetic predisposition is only limited to exfoliation with or without glaucoma and does not include the POAG phenotype.…”
Publicado 2008
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702678“…The combined effect of these factors may contribute to incomplete digestion, thereby limiting the absorption rate of protein before it reaches the ceacum and is eliminated as waste. …”
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702679por Brand, Richard A.“…Luke’s Hospital. He continued limited practice and served as a consultant at the Clinic up until the time of his death. …”
Publicado 2008
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702680“…Consequently, at the turn of the millennium, points of robust agreement among schools concerning higher-order neornithine phylogeny have been limited to the two basalmost and several mid-level, primary groups. …”
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