“…Finally, the 3D volume measurement may provide additional information about the size of TNs for longitudinal follow-up of nodules with benign FNAB. The limitations or challenges of using 3D US in general practice include the cost of the ultrasound machine, lack of reimbursement, and the provider's learning curve. …”
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“…CONCLUSIONS: There remains a paucity of literature to help guide surgical treatment of symptomatic mesoacromion. Studies are largely limited to retrospective reviews and case series with various surgical techniques utilized. …”
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“…Additionally, blood flow measurements are only limited time assessments with no ability to speculate if observed changes are permanent or temporary. …”
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“…Reports on the effect of time delay on clinical outcomes, however, remain limited. Therefore, the purpose of this study was to evaluate the effect of time delay from cartilage biopsy to implantation on patient satisfaction, return to sport (RTS), and clinical outcomes following autologous chondrocyte implantation. …”
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“…Peri-operative complications for ITB-ACLR+ALLR included 1 case of graft rupture 8 months post-operatively, which was associated with patient non-compliance with post-operative rehabilitation protocols/limitations (subsequently treated with revision BTB-ACLR), 1 case of medial meniscus tear 11 months post-operatively (subsequently treated with partial meniscectomy), 1 case of lateral thigh cramping at 6 weeks post-operatively (resolved spontaneously within 1 week), one cases of stiffness at 3 months post-operatively (resolved with dynamic bracing and PT), and one superficial wound infection at 2 weeks post-operatively (resolved with oral antibiotics). …”
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“…If the duration of protection was limited to 10 years, then costs increased to $21,121 per QALY. …”
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“…Analyses of the 3 essential drug classes were limited to members with at least 1 claim in the drug class in both the pre-change and post-change periods (N=11,917, intervention group; 1,792, comparison group), and assessed per patient per month (PPPM) days supply, beneficiary cost, employer cost, and total cost. …”
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“…Both the level of cumulative AUC(PACU-48 h) (at rest: 160.08 ± 38.00 vs. 164.94 ± 31.00; difference [90% CI], −4.861 [−16.308, 6.585]) and cumulative AUC(PACU-48 h) (at movement: 209.64 ± 28.98 vs. 212.59 ± 33.11; difference [90% CI], −2.948 [−13.236, 7.339]) were similar between the VC-ESPB and control groups within the first postoperative 48 h. The upper limit of the 90% CIs for the difference in cumulative ACUP(ACU-48 h) at rest and at movement did not reach the upper inferiority margin (26.5). …”
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“…TB prevalence was higher among people living with HIV than HIV–negative individuals, with an age-sex-community adjusted odds ratio of 2.29 [95% CI 1.54, 3.41] in Zambian communities and 1.61 [95% CI 1.13, 2.30] in South African communities. The primary limitations are that the study was powered to detect only large reductions in TB prevalence in the intervention arm compared with standard-of-care, and the between-community variation in TB prevalence was larger than anticipated. …”
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“…LARGE SCALE DATA: The raw miRNA sequence data reported in this article have been deposited in the Genome Sequence Archive (GSA-Human: HRA005227) and are publicly accessible at https://ngdc.cncb.ac.cn/gsa-human/browse/HRA005227. LIMITATIONS, REASONS FOR CAUTION: Although the RNA sequencing results revealed the global dynamic changes of miRNA expression, further experiments examining the clinical significance of the identified DE miRNAs in embryo implantation outcome and the relevant regulatory mechanisms involved are warranted. …”
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“…Traditional immunosuppressants have limited efficacy, but vasculitic manifestations have been reported to respond to biologic TNF-inhibitors. …”
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“…The initial impression was that she had developed a side effect to zoledronate which would be self limiting and she was treated with over the counter analgesics. …”
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“…However, there has been limited focus on the rarer occurrence of rheumatoid involvement in the thoracic and lumbar regions. …”
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“…Study population included patients with diabetes and ≥1 TG value, stratified by first TG value (<500, 500-999, ≥1000 mg/dL); for selected analyses, patients were limited to those with multiple TG values. Study measures were assessed beginning with the first TG value and included: number of TG tests (all patients), days between tests (patients with ≥2 TG values), TG values by test (all patients), and TG values across tests (patients with ≥3 TG values receiving statins only or TG-targeting therapy only [fenofibrate, fenofibric acid, icosapent ethyl, gemibrozil, omega-3 fatty acid]). …”
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“…The applicability of evidence from single-strain challenge trials to field practices is limited. Despite the synthesis of six outcomes, challenge trial evidence does not support or refute vaccination of sows against influenza to protect piglets. …”
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“…Grants awarded to Zucker Hillside Hospital/Feinstein Institutes for Medical Research during the conduct of the brexanolone injection and zuranolone clinical trials (Sage Therapeutics), Consultant of: Sage Therapeutics, Inc., Brii Biosciences, Inc., and GH Research Ireland Limited, J. A. Ramos-Quiroga Grant / Research support from: The Department of Mental Health chaired by him received unrestricted educational and research support from the following companies in the last 3 years: Janssen-Cilag, Shire, Oryzon, Roche, Psious, and Rubió. …”
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“…MAIN RESULTS AND THE ROLE OF CHANCE: The multidisciplinary working group formulated 42 recommendations in three sections; diagnosis and diagnostic tests, laboratory tests and interventions, and clinical management. LIMITATIONS, REASONS FOR CAUTION: Of the 42 recommendations, none could be based on high-quality evidence and only four could be based on moderate-quality evidence, implicating that 95% of the recommendations are supported only by low-quality randomized controlled trials, observational data, professional experience, or consensus of the development group. …”
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“…[Figure: see text] [Figure: see text] CONCLUSION: Virologic response with FTR + OBT in HTE adults with advanced HIV-1 and limited treatment options was durable over ∼5 years, with no major differences among subgroups based on age, sex, race, or geographic region. …”
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“…|BIOFIRE: Grant/Research Support|CARB-X: Advisor/Consultant|ContraFect: Grant/Research Support|Day Zero Diagnostics: Advisor/Consultant|HealthTrackRx: Advisor/Consultant|Mammoth Biosciences: Advisor/Consultant|Netflix: Advisor/Consultant|Oxford Nanopore Technologies: Advisor/Consultant|PhAST: Advisor/Consultant|See details: Patent on Bordetella pertussis/parapertussis PCR issued, a patent on a device/method for sonication with royalties paid by Samsung to Mayo Clinic|See details: continued, patent on an anti-biofilm substance issued|TenNor Therapeutics Limited: Grant/Research Support|Torus Biosystems: Advisor/Consultant|Trellis Bioscience, Inc.: Advisor/Consultant…”
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“…CONCLUSION: CFDC was a highly active β-lactam against contemporary pediatric isolates of Enterobacterales, P. aeruginosa, ABC, and S. maltophilia, including CarbNS subsets for which treatment options are limited. These data suggest CFDC may be a valuable treatment for serious Gram-negative infections in pediatric patients. …”
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