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  1. 703221
    “…LARGE-SCALE DATA: N/A. LIMITATIONS, REASONS FOR CAUTION: This study focuses on non-growing follicle activation after 6 days culture and may not reflect DNA damage and repair capacity in later stages of oocyte and follicle growth. …”
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  2. 703222
    “…Restrictively fed gestating sows are unlikely to be sated, and are more likely to view food as a limited resource and to be frustrated and aggressive. …”
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  3. 703223
    “…Neonatal congenital anomalies were observed in 1/46 (2.1%) of babies in the rhG-CSF group versus 1/49 (2.0%) in the placebo group (RR of 0.9; 95% CI: 0.1–13.4; P = 0.93). LIMITATIONS, REASONS FOR CAUTION: This trial was conducted in women diagnosed with unexplained recurrent pregnancy loss and therefore no screening tests (commercially available) were performed for immune dysfunction related pregnancy failure/s. …”
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  4. 703224
    “…LARGE SCALE DATA: N/A. LIMITATIONS, REASONS FOR CAUTION: Although xenotransplantation of marmoset ITT was successful, it does not fully reflect all aspects of a future clinical setting. …”
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  5. 703225
    “…The cumulative live birth rate per started cycle was similar (32 and 35%) comparing the individualized with the standard group. LIMITATIONS, REASONS FOR CAUTION: This study was powered for showing differences only in the distribution of oocyte retrieval when comparing individualized and standard groups, therefore additional results should be viewed with caution. …”
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  6. 703226
    por Wides, Ron
    Publicado 2019
    “…As a second of three ‘footnotes’: a limited number of species exist with additional Teneurin gene copies. …”
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  7. 703227
    Publicado 2019
    “…INTERPRETATION: Statin therapy produces significant reductions in major vascular events irrespective of age, but there is less direct evidence of benefit among patients older than 75 years who do not already have evidence of occlusive vascular disease. This limitation is now being addressed by further trials. …”
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  8. 703228
    “…AIMS/HYPOTHESIS: Evidence for the effectiveness of interstitial glucose monitoring in individuals with type 1 diabetes using multiple daily injection (MDI) therapy is limited. In this pre-specified subgroup analysis of the Novel Glucose-Sensing Technology and Hypoglycemia in Type 1 Diabetes: a Multicentre, Non-masked, Randomised Controlled Trial’ (IMPACT), we assessed the impact of flash glucose technology on hypoglycaemia compared with capillary glucose monitoring. …”
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  9. 703229
    “…Resistance tests (genotypic or phenotypic) are widely used in high‐income countries, but not in resource‐limited settings. This systematic review summarizes the relative merits of resistance testing in treatment‐naive and treatment‐exposed people living with HIV. …”
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  10. 703230
    “…There were no differences between women with or without microchimerism in occurrence of alternative sources of XY cells, such as older brothers, previous blood transfusion, or history of sexual intercourse. LIMITATIONS, REASON FOR CAUTION: We are not able to draw definitive conclusions regarding the occurrence of AMH exchange during embryologic development in women with MRKH syndrome. …”
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  11. 703231
    por Gameiro, S, Sousa-Leite, M, Vermeulen, N
    Publicado 2019
    “…Results for the clinicians only showed that, despite less knowledge about the RPC guideline, they were more likely to download all the guidelines, to follow them, make changes in their daily practice and refer them to their patients. LIMITATIONS, REASONS FOR CAUTION: Respondents were ESHRE members and these are not representative of all European reproductive health professionals. …”
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  12. 703232
  13. 703233
    “…There was little evidence for an association of genetic liability to type 2 diabetes, parity, or circulating levels of 25-hydroxyvitamin D and sex hormone binding globulin with ovarian cancer or its subtypes. The primary limitations of this analysis include the modest statistical power for analyses of risk factors in relation to some less common ovarian cancer histotypes (low grade serous, mucinous, and clear cell carcinomas), the inability to directly examine the association of some ovarian cancer risk factors that did not have robust genetic variants available to serve as proxies (e.g., oral contraceptive use, hormone replacement therapy), and the assumption of linear relationships between risk factors and ovarian cancer risk. …”
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  14. 703234
    “…However, trends observed in the care content varied widely by indicator and did not always match the large apparent increases observed in care seeking behavior, particularly for antenatal care, reflecting important gaps in the provision of essential health services for individuals who sought care. The main limitation of this study is that the intervention catchment was not randomly allocated, and some demographic indicators were better for this group at baseline than for the rest of the district, which could have impacted the trends observed. …”
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  15. 703235
    “…Glucocorticoid therapy is the mainstay treatment for large vessel vasculitis, but side-effects can be limiting. Steroid sparing agents, such as IL-6 inhibitors should be considered early as an alternative immunosuppressant for patients with large vessel vasculitis. …”
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  16. 703236
    “…Her exercise tolerance was limited to 50 metres over the past 2 months and she had rest pain. …”
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  17. 703237
    por Hoey, Mark, McHenry, Michelle
    Publicado 2019
    “…She was diagnosed as having chronic spontaneous angioedema and occasional urticaria and commenced on omalizumab therapy with limited benefit. She attended dermatology in February 2018. …”
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  18. 703238
    por Onac, Ioana, Hajela, Vijay
    Publicado 2019
    “…Methotrexate should probably have been started once the limited response to IV steroids was apparent. Antiplatelet agents are no longer recommended in the updated BSR guidelines for managing GCA. …”
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  19. 703239
    “…Uncontrolled inflammatory disease is associated with pregnancy morbidity and very limited information is available about the short and long-term safety of treatments for autoinflammatory diseases in general. …”
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  20. 703240
    “…The fact that it must be presumed that the majority of diagnoses of prosopagnosia have been made on the basis of patients’ self-reports and clinicians’ judgments represents a limiting factor in this study. We are currently exploring machine-learning strategies to identify potential false-negative cases among the patients with surrogate diagnoses. …”
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