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703381por Al-Rifai, Rami H., Alhosani, Farida, Abuyadek, Rowan, Atef, Shereen, Donnelly, James G., Leinberger-Jabari, Andrea, Ahmed, Luai A., Altrabulsi, Basel, Alatoom, Adnan, Alsuwaidi, Ahmed R., AbdelWareth, Laila“…CONCLUSION: Achieving and maintaining a high blood concentration of protective immune biomarkers that predict vaccine effectiveness is very critical to limit transmission and contain outbreaks. In this study, boosting with only one dose or with only BBIBP-CorV after priming with BBIBP-CorV was insufficient, whereas boosting with two doses, particularly boosting with the mRNA-based vaccine, was shown to be associated with having a high concentration of anti-S, anti-N, and neutralizing IgG antibodies and producing an efficient T-cell response.…”
Publicado 2023
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703382“…This may be due in part to limited access to healthcare from isolation and a shift to telemedicine during that time. …”
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703383por Bordewijk, E M, Jannink, T I, Weiss, N S, de Vries, T, Nahuis, M, Hoek, A, Goddijn, M, Mol, B W, van Wely, M“…In the IUI group, a first live birth occurred in 158 of 192 women (82.3%) and while in the intercourse group, 146 of 182 women (80.2%) reached at least one live birth (RR: 1.03 95% CI 0.93–1.13; 2.13%, 95% CI −5.95, 10.21). LIMITATIONS, REASONS FOR CAUTION: We have complete follow-up results for 57% of the women. …”
Publicado 2023
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703384por Raja, Edwin-Amalraj, Bhattacharya, Siladitya, Maheshwari, Abha, McLernon, David J“…However, we could not confirm an association between blastocyst stage ET and low birthweight (1.35; 0.81, 2.27), high birthweight (1.19; 0.80, 1.77), and the chance of being a healthy baby (0.97; 0.86, 1.09). LIMITATIONS, REASONS FOR CAUTION: This was an observational study where we were unable to adjust for some key confounders, such as maternal smoking status and BMI, which may change from one pregnancy to another and are not recorded in the HFEA dataset. …”
Publicado 2023
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703385por Abreu, P., Adam, W., Adye, T., Adzic, P., Ajinenko, I., Albrecht, Z., Alderweireld, T., Alekseev, G.D., Alemany, R., Allmendinger, T., Allport, P.P., Almehed, S., Amaldi, U., Amapane, N., Amato, S., Anassontzis, E.G., Andersson, P., Andreazza, A., Andringa, S., Antilogus, P., Apel, W.D., Arnoud, Y., Asman, B., Augustin, J.E., Augustinus, A., Baillon, P., Bambade, P., Barao, F., Barbiellini, G., Barbier, R., Bardin, Dmitri Yu., Barker, G.J., Baroncelli, A., Battaglia, M., Baubillier, M., Becks, K.H., Begalli, M., Behrmann, A., Beilliere, P., Belokopytov, Yu., Benekos, N.C., Benvenuti, A.C., Berat, C., Berggren, M., Bertini, D., Bertrand, D., Besancon, M., Bigi, M., Bilenky, Mikhail S., Bizouard, M.A., Bloch, D., Blom, H.M., Bonesini, M., Bonivento, W., Boonekamp, M., Booth, P.S.L., Borgland, A.W., Borisov, G., Bosio, C., Botner, O., Boudinov, E., Bouquet, B., Bourdarios, C., Bowcock, T.J.V., Boyko, I., Bozovic, I., Bozzo, M., Bracko, M., Branchini, P., Brenke, T., Brenner, R.A., Bruckman, P., Brunet, J.M., Bugge, L., Buran, T., Burgsmueller, T., Buschbeck, B., Buschmann, P., Cabrera, S., Caccia, M., Calvi, M., Camporesi, T., Canale, V., Carena, F., Carroll, L., Caso, C., Castillo Gimenez, M.V., Cattai, A., Cavallo, F.R., Chabaud, V., Charpentier, P., Chaussard, L., Checchia, P., Chelkov, G.A., Chierici, R., Chliapnikov, P., Chochula, P., Chorowicz, V., Chudoba, J., Cieslik, K., Collins, P., Contri, R., Cortina, E., Cosme, G., Cossutti, F., Crawley, H.B., Crennell, D., Crepe-Renaudin, Sabine, Crosetti, G., Cuevas Maestro, J., Czellar, S., Davenport, M., Da Silva, W., Deghorain, A., Della Ricca, G., Delpierre, P., Demaria, N., De Angelis, A., De Boer, W., De Clercq, C., De Lotto, B., De Min, A., De Paula, L., Dijkstra, H., Di Ciaccio, L., Dolbeau, J., Doroba, K., Dracos, M., Drees, J., Dris, M., Duperrin, A., Durand, J.D., Eigen, G., Ekelof, T., Ekspong, G., Ellert, M., Elsing, M., Engel, J.P., Espirito Santo, M.C., Fanourakis, G., Fassouliotis, D., Fayot, J., Feindt, M., Fenyuk, A., Ferrari, P., Ferrer, A., Ferrer-Ribas, E., Ferro, F., Fichet, S., Firestone, A., Flagmeyer, U., Foeth, H., Fokitis, E., Fontanelli, F., Franek, B., Frodesen, A.G., Fruhwirth, R., Fulda-Quenzer, F., Fuster, J., Galloni, A., Gamba, D., Gamblin, S., Gandelman, M., Garcia, C., Gaspar, C., Gaspar, M., Gasparini, U., Gavillet, P., Gazis, Evangelos, Gele, D., Ghodbane, N., Gil Botella, Ines, Glege, F., Gokieli, R., Golob, B., Gomez-Ceballos, G., Goncalves, P., Gonzalez Caballero, I., Gopal, G., Gorn, L., Gouz, Yu., Gracco, V., Grahl, J., Graziani, E., Grimm, H.J., Gris, P., Grosdidier, G., Grzelak, K., Gunther, M., Guy, J., Hahn, F., Hahn, S., Haider, S., Hallgren, A., Hamacher, K., Hansen, J., Harris, F.J., Hedberg, V., Heising, S., Hernandez, J.J., Herquet, P., Herr, H., Hessing, T.L., Heuser, J.M., Higon, E., Holmgren, S.O., Holt, P.J., Hoorelbeke, S., Houlden, M., Hrubec, J., Huet, K., Hughes, G.J., Hultqvist, K., Jackson, John Neil, Jacobsson, R., Jalocha, P., Janik, R., Jarlskog, C., Jarlskog, G., Jarry, P., Jean-Marie, B., Jeans, D., Johansson, Erik Karl, Jonsson, P., Joram, C., Juillot, P., Kapusta, Frederic, Karafasoulis, K., Katsanevas, S., Katsoufis, E.C., Keranen, R., Kernel, G., Kersevan, B.P., Khomenko, B.A., Khovanski, N.N., Kiiskinen, A., King, B., Kinvig, A., Kjaer, N.J., Klapp, O., Klein, Hansjorg, Kluit, P., Kokkinias, P., Koratzinos, M., Kostioukhine, V., Kourkoumelis, C., Kouznetsov, O., Krammer, M., Kriznic, E., Krumstein, Z., Kubinec, P., Kurowska, J., Kurvinen, K., Lamsa, J.W., Lane, D.W., Langefeld, P., Lapin, V., Laugier, J.P., Lauhakangas, R., Leder, G., Ledroit, Fabienne, Lefebure, V., Leinonen, L., Leisos, A., Leitner, R., Lemonne, J., Lenzen, G., Lepeltier, V., Lesiak, T., Lethuillier, M., Libby, J., Liko, D., Lipniacka, A., Lippi, I., Loerstad, B., Loken, J.G., Lopes, J.H., Lopez, J.M., Lopez-Fernandez, R., Loukas, D., Lutz, P., Lyons, L., MacNaughton, J., Mahon, J.R., Maio, A., Malek, A., Malmgren, T.G.M., Maltezos, S., Malychev, V., Mandl, F., Marco, J., Marco, R., Marechal, B., Margoni, M., Marin, J.C., Mariotti, C., Markou, A., Martinez-Rivero, C., Martinez-Vidal, F., Marti i Garcia, S., Masik, J., Mastroyiannopoulos, N., Matorras, F., Matteuzzi, C., Matthiae, G., Mazzucato, F., Mazzucato, M., McCubbin, M., McKay, R., McNulty, R., McPherson, G., Meroni, C., Meyer, W.T., Miagkov, A., Migliore, E., Mirabito, L., Mitaroff, W.A., Mjoernmark, U., Moa, T., Moch, M., Moller, Rasmus, Monig, Klaus, Monge, M.R., Moreau, X., Morettini, P., Morton, G., Mueller, U., Muenich, K., Mulders, M., Mulet-Marquis, C., Muresan, R., Murray, W.J., Muryn, B., Myatt, G., Myklebust, T., Naraghi, F., Nassiakou, M., Navarria, F.L., Navas, Sergio, Nawrocki, K., Negri, P., Neufeld, N., Nicolaidou, R., Nielsen, B.S., Niezurawski, P., Nikolenko, M., Nomokonov, V., Nygren, A., Obraztsov, V., Olshevski, A.G., Onofre, A., Orava, R., Orazi, G., Osterberg, K., Ouraou, A., Paganoni, M., Paiano, S., Pain, R., Paiva, R., Palacios, J., Palka, H., Papadopoulou, T.D., Papageorgiou, K., Pape, L., Parkes, C., Parodi, F., Parzefall, U., Passeri, A., Passon, O., Pavel, T., Pegoraro, M., Peralta, L., Pernicka, M., Perrotta, A., Petridou, C., Petrolini, A., Phillips, H.T., Pierre, F., Pimenta, M., Piotto, E., Podobnik, T., Pol, M.E., Polok, G., Poropat, P., Pozdniakov, V., Privitera, P., Pukhaeva, N., Pullia, A., Radojicic, D., Ragazzi, S., Rahmani, H., Rames, J., Ratoff, P.N., Read, Alexander L., Rebecchi, P., Redaelli, Nicola Giuseppe, Regler, M., Reid, D., Reinhardt, R., Renton, P.B., Resvanis, L.K., Richard, F., Ridky, J., Rinaudo, G., Rohne, O., Romero, A., Ronchese, P., Rosenberg, E.I., Rosinsky, P., Roudeau, P., Rovelli, T., Royon, C., Ruhlmann-Kleider, V., Ruiz, A., Saarikko, H., Sacquin, Y., Sadovsky, A., Sajot, G., Salt, J., Sampsonidis, D., Sannino, M., Schneider, H., Schwemling, P., Schwering, B., Schwickerath, U., Scuri, Fabrizio, Seager, P., Sedykh, Y., Segar, A.M., Sekulin, R., Shellard, R.C., Siebel, M., Simard, L., Simonetto, F., Sisakian, A.N., Smadja, G., Smirnov, N., Smirnova, O., Smith, G.R., Sokolov, A., Sopczak, A., Sosnowski, R., Spassov, T., Spiriti, E., Sponholz, P., Squarcia, S., Stanescu, C., Stanic, S., Stevenson, K., Stocchi, A., Strauss, J., Strub, R., Stugu, B., Szczekowski, M., Szeptycka, M., Tabarelli, T., Taffard, A., Tegenfeldt, F., Terranova, F., Thomas, J., Timmermans, Jan, Tinti, N., Tkatchev, L.G., Tobin, M., Todorova, S., Tomaradze, A., Tome, B., Tonazzo, A., Tortora, L., Tortosa, P., Transtromer, G., Treille, D., Tristram, G., Trochimczuk, M., Troncon, C., Tsirou, A., Turluer, M.L., Tyapkin, I.A., Tzamarias, S., Ullaland, O., Uvarov, V., Valenti, G., Vallazza, E., Vander Velde, C., Van Apeldoorn, G.W., Van Dam, Piet, Van Den Boeck, W., Van Doninck, Walter, Van Eldik, J., Van Lysebetten, A., Van Remortel, N., Van Vulpen, I., Vegni, G., Ventura, L., Venus, W., Verbeure, F., Verlato, M., Vertogradov, L.S., Verzi, V., Vilanova, D., Vitale, L., Vlasov, E., Vodopianov, A.S., Vollmer, C., Voulgaris, G., Vrba, V., Wahlen, H., Walck, C., Washbrook, A.J., Weiser, C., Wicke, D., Wickens, J.H., Wilkinson, G.R., Winter, M., Witek, M., Wolf, G., Yi, J., Yushchenko, O., Zalewska, A., Zalewski, P., Zavrtanik, D., Zevgolatakos, E., Zimine, N.I., Zintchenko, A., Zucchelli, G.C., Zumerle, G.Enlace del recurso
Publicado 2000
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703386por Lee, Eun-Ju, Beltrami Moreira, Marina, Al-Samkari, Hanny, Cuker, Adam, MacWhirter - DiRaimo, Jennifer, Gernsheimer, Terry B., Kruse, Alexandra, Kessler, Craig M., Kruse, Caroline, Leavitt, Andrew D, Lee, Alfred Ian, Liebman, Howard A., Newland, Adrian C., Ray, Ashley E., Tarantino, Michael D, Thachil, Jecko, Kuter, David J., Cines, Douglas B., Bussel, James B“…Published reports are limited but suggest that most patients with ITP tolerate the COVID-19 vaccines well without frequent ITP exacerbations (Kuter, BJH, 2021). …”
Publicado 2021
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703387por Russell, Neal J., Stöhr, Wolfgang, Plakkal, Nishad, Cook, Aislinn, Berkley, James A., Adhisivam, Bethou, Agarwal, Ramesh, Ahmed, Nawshad Uddin, Balasegaram, Manica, Ballot, Daynia, Bekker, Adrie, Berezin, Eitan Naaman, Bilardi, Davide, Boonkasidecha, Suppawat, Carvalheiro, Cristina G., Chami, Neema, Chaurasia, Suman, Chiurchiu, Sara, Colas, Viviane Rinaldi Favarin, Cousens, Simon, Cressey, Tim R., de Assis, Ana Carolina Dantas, Dien, Tran Minh, Ding, Yijun, Dung, Nguyen Trong, Dong, Han, Dramowski, Angela, DS, Madhusudhan, Dudeja, Ajay, Feng, Jinxing, Glupczynski, Youri, Goel, Srishti, Goossens, Herman, Hao, Doan Thi Huong, Khan, Mahmudul Islam, Huertas, Tatiana Munera, Islam, Mohammad Shahidul, Jarovsky, Daniel, Khavessian, Nathalie, Khorana, Meera, Kontou, Angeliki, Kostyanev, Tomislav, Laoyookhon, Premsak, Lochindarat, Sorasak, Larsson, Mattias, Luca, Maia De, Malhotra-Kumar, Surbhi, Mondal, Nivedita, Mundhra, Nitu, Musoke, Philippa, Mussi-Pinhata, Marisa M., Nanavati, Ruchi, Nakwa, Firdose, Nangia, Sushma, Nankunda, Jolly, Nardone, Alessandra, Nyaoke, Borna, Obiero, Christina W., Owor, Maxensia, Ping, Wang, Preedisripipat, Kanchana, Qazi, Shamim, Qi, Lifeng, Ramdin, Tanusha, Riddell, Amy, Romani, Lorenza, Roysuwan, Praewpan, Saggers, Robin, Roilides, Emmanuel, Saha, Samir K., Sarafidis, Kosmas, Tusubira, Valerie, Thomas, Reenu, Velaphi, Sithembiso, Vilken, Tuba, Wang, Xiaojiao, Wang, Yajuan, Yang, Yonghong, Zunjie, Liu, Ellis, Sally, Bielicki, Julia A., Walker, A. Sarah, Heath, Paul T., Sharland, Mike“…BACKGROUND: There is limited data on antibiotic treatment in hospitalized neonates in low- and middle-income countries (LMICs). …”
Publicado 2023
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703388por Geerlings, Angelika D., Kapelle, Willanka M., Sederel, Charlotte J., Tenison, Emma, Wijngaards-Berenbroek, Hilde, Meinders, Marjan J., Munneke, Marten, Ben-Shlomo, Yoav, Bloem, Bastiaan R., Darweesh, Sirwan K. L.“…Integration of both data strands revealed that qualitative findings expanded quantitative findings by (1) distinguishing between the impact of the relationship with the person with PD and the relationship with others on perceived social support, (2) revealing the impact of non-motor symptoms next to motor symptoms and (3) revealing the following additional factors impacting caregiver burden: concern about the future, perceived restrictions and limitations in performing daily activities due to the disease, and negative feelings and emotional well-being. …”
Publicado 2023
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703389por Kim, Jeongrae, Song, Sunejeong, Gwak, Minjun, Cho, Hanhee, Yun, Wan Su, Hwang, Namcheol, Kim, Jinseong, Lee, Jun Seo, Kim, Dong-Hwee, Kim, Hyuncheol, Jeon, Seong Ik, Kim, Tae-il, Kim, Kwangmeyung“…The MSC-guided administration of anticancer drug-encapsulated LNPs is expected to be a potent platform system that facilitates overcoming the limitations of systemic drug administration with low delivery efficiency and serious side effects. …”
Publicado 2023
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703390por Slogrove, Amy L., Schomaker, Michael, Davies, Mary-Ann, Williams, Paige, Balkan, Suna, Ben-Farhat, Jihane, Calles, Nancy, Chokephaibulkit, Kulkanya, Duff, Charlotte, Eboua, Tanoh François, Kekitiinwa-Rukyalekere, Adeodata, Maxwell, Nicola, Pinto, Jorge, Seage, George, Teasdale, Chloe A., Wanless, Sebastian, Warszawski, Josiane, Wools-Kaloustian, Kara, Yotebieng, Marcel, Timmerman, Venessa, Collins, Intira J., Goodall, Ruth, Smith, Colette, Patel, Kunjal, Paul, Mary, Gibb, Diana, Vreeman, Rachel, Abrams, Elaine J., Hazra, Rohan, Van Dyke, Russell, Bekker, Linda-Gail, Mofenson, Lynne, Vicari, Marissa, Essajee, Shaffiq, Penazzato, Martina, Anabwani, Gabriel, Q. Mohapi, Edith, N. Kazembe, Peter, Hlatshwayo, Makhosazana, Lumumba, Mwita, Goetghebuer, Tessa, Thorne, Claire, Galli, Luisa, van Rossum, Annemarie, Giaquinto, Carlo, Marczynska, Magdalena, Marques, Laura, Prata, Filipa, Ene, Luminita, Okhonskaia, Liubov, Rojo, Pablo, Fortuny, Claudia, Naver, Lars, Rudin, Christoph, Le Coeur, Sophie, Volokha, Alla, Rouzier, Vanessa, Succi, Regina, Sohn, Annette, Kariminia, Azar, Edmonds, Andrew, Lelo, Patricia, Ayaya, Samuel, Ongwen, Patricia, Jefferys, Laura F., Phiri, Sam, Mubiana-Mbewe, Mwangelwa, Sawry, Shobna, Renner, Lorna, Sylla, Mariam, Abzug, Mark J., Levin, Myron, Oleske, James, Chernoff, Miriam, Traite, Shirley, Purswani, Murli, Chadwick, Ellen G., Judd, Ali, Leroy, Valériane“…However, LTFU was lowest in South America and the Caribbean (4.8% [3.4%–6.7%]) and highest in sub-Saharan Africa (13.2% [12.6%–13.7%]). Study limitations include the high LTFU rate in sub-Saharan Africa, which could have affected the comparison of mortality across regions; inclusion of data only for APHs receiving ART from some countries; and unavailability of data from high-burden countries such as Nigeria. …”
Publicado 2018
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703391por Davies, Justine I., Reddiar, Sumithra Krishnamurthy, Hirschhorn, Lisa R., Ebert, Cara, Marcus, Maja-Emilia, Seiglie, Jacqueline A., Zhumadilov, Zhaxybay, Supiyev, Adil, Sturua, Lela, Silver, Bahendeka K., Sibai, Abla M., Quesnel-Crooks, Sarah, Norov, Bolormaa, Mwangi, Joseph K., Omar, Omar Mwalim, Wong-McClure, Roy, Mayige, Mary T., Martins, Joao S., Lunet, Nuno, Labadarios, Demetre, Karki, Khem B., Kagaruki, Gibson B., Jorgensen, Jutta M. A., Hwalla, Nahla C., Houinato, Dismand, Houehanou, Corine, Guwatudde, David, Gurung, Mongal S., Bovet, Pascal, Bicaba, Brice W., Aryal, Krishna K., Msaidié, Mohamed, Andall-Brereton, Glennis, Brian, Garry, Stokes, Andrew, Vollmer, Sebastian, Bärnighausen, Till, Atun, Rifat, Geldsetzer, Pascal, Manne-Goehler, Jennifer, Jaacks, Lindsay M.“…Of the 27 associations tested between facility preparedness indicators and outcomes, the only association that was significant was having metformin available, which was positively associated with treatment (OR, 1.35 [95% CI 1.01–1.81], p = 0.04). The main limitation was use of blood pressure measurement on a single occasion to diagnose hypertension and a single blood glucose measurement to diagnose diabetes. …”
Publicado 2020
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703392por Hsieh, Szu-Min, Liu, Ming-Che, Chen, Yen-Hsu, Lee, Wen-Sen, Hwang, Shinn-Jang, Cheng, Shu-Hsing, Ko, Wen-Chien, Hwang, Kao-Pin, Wang, Ning-Chi, Lee, Yu-Lin, Lin, Yi-Ling, Shih, Shin-Ru, Huang, Chung-Guei, Liao, Chun-Che, Liang, Jian-Jong, Chang, Chih-Shin, Chen, Charles, Lien, Chia En, Tai, I-Chen, Lin, Tzou-Yien“…Exclusion criteria included (but were not limited to) travel overseas within 14 days of screening, intention to travel overseas within 6 months of the screening visit, and the absence of prespecified medical conditions, including immunosuppressive illness, a history of autoimmune disease, malignancy with risk to recur, a bleeding disorder, uncontrolled HIV infection, uncontrolled hepatitis B and C virus infections, SARS-CoV-1 or SARS-CoV-2 infections, an allergy to any vaccine, or a serious medical condition that could interfere with the study. …”
Publicado 2021
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703393por van Hoogenhuijze, N E, van Eekelen, R, Mol, F, Schipper, I, Groenewoud, E R, Traas, M A F, Janssen, C A H, Teklenburg, G, de Bruin, J P, van Oppenraaij, R H F, Maas, J W M, Moll, E, Fleischer, K, van Hooff, M H A, de Koning, C H, Cantineau, A E P, Lambalk, C B, Verberg, M, van Heusden, A M, Manger, A P, van Rumste, M M E, van der Voet, L F, Pieterse, Q D, Visser, J, Brinkhuis, E A, den Hartog, J E, Glas, M W, Klijn, N F, van der Zanden, M, Bandell, M L, Boxmeer, J C, van Disseldorp, J, Smeenk, J, van Wely, M, Eijkemans, M J C, Torrance, H L, Broekmans, F J M“…The ICER estimate was surrounded with a high level of uncertainty, as indicated by the fact that the cost-effectiveness acceptability curve (CEAC) showed that there is an 80% chance that endometrial scratching is cost-effective if society is willing to pay ∼€17 500 for each additional live birth. LIMITATIONS, REASONS FOR CAUTION: There was a high uncertainty surrounding the effects, mainly in the clinical effect, i.e. the difference in the chance of live birth, which meant that a single straightforward conclusion could not be ascertained as for now. …”
Publicado 2021
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703394Publicado 2022“…The results of the study should be interpreted with the limitations of it being a single centre study with assessment of only inpatients and cross-sectional design of the study. …”
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703396por Policicchio, Antonio“…The effective Hamiltonian, in the heavy quark limit, is introduced and the methods to compute the perturbative short-distance and the non-perturbative long-distance contributions are discussed. …”
Publicado 2006
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703397por Paniccia, Mercedes“…De plus, les données recueillies ont apporté des mesures précises des spectres des rayons cosmiques chargés dans l’intervalle d’énergie allant de 100 MeV per nucleon à 200 GeV per nucleon, et ont permis d’établir la meilleure limite, à l’époque, sur l’existence de l’antimatière. …”
Publicado 2011
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703398por Grippo, Maria Teresa“…Visti i risultati di Dicembre 2011 \cite{limiteCMS} , la ricerca del bosone di Higgs è ormai concentrata nell'intervallo a bassa massa. …”
Publicado 2013
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703399por Neven, Michiel“…An attempt was also made for extracting the diagonal matrix element, related to the quadrupole moment of the populated state, but since only a limited angular range of the DSSSD could be used no conclusion could be drawn. …”
Publicado 2017
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703400“…Part IBiomaterials ScienceBiomaterials Science and EngineeringLearning ObjectivesMaterials Science and EngineeringMultilevels of Structure and Categorization of MaterialsFour Categories of MaterialsDefinitions of Biomaterials, Biomedical Materials, and Biological MaterialsBiocompatibilityChapter HighlightsActivitiesSimple Questions in ClassProblems and ExercisesBibliographyToxicity and CorrosionLearning ObjectivesElements in the BodyBiological Roles and Toxicities of Trace ElementsSelection of Metallic Elements in Medical-Grade AlloysCorrosion of MetalsEnvironment inside the BodyMinimization of Toxicity of Metal ImplantsChapter HighlightsLaboratory Practice 1Simple Questions in ClassProblems and ExercisesAdvanced Topic: Biological Roles of Alloying ElementsBibliographyMechanical Properties of BiomaterialsLearning ObjectivesRole of Implant BiomaterialsMechanical Properties of General ImportanceHardnessElasticity: Resilience and StrechabilityMechanical Properties Terms Used in the Medical CommunityFailureEssential Mechanical Properties of Orthopedic Implant BiomaterialsChapter HighlightsActivitiesSimple Questions in ClassProblems and ExercisesBibliographyMetallic Biomaterials in Orthopedic ImplantsLearning ObjectivesDevelopment of Metallic BiomaterialsStainless SteelsCobalt-Based AlloysTitanium AlloysComparison of Stainless Steels, Cobalt, and Titanium AlloysSummary and RemarksChapter HighlightsActivitiesSimple Questions in ClassProblems and ExercisesBibliographyMetallic Biomaterials: Miscellaneous OthersLearning ObjectivesDental MaterialsNiTi Shape-Memory AlloysOther Clinically Applied Metallic MaterialsNew Metallic Materials: Magnesium AlloysChapter HighlightsLaboratory Practice 2Simple Questions in ClassProblems and ExercisesBibliographyBioinert CeramicsLearning ObjectivesOverview of BioceramicsInert Bioceramics: Al2O3Inert Bioceramics: ZrO2Two Types of JointsSummary and Remarks on Al2O3 and ZrO2Dental CeramicsChapter HighlightsActivitiesSimple Questions in ClassProblems and ExercisesAdvanced Topic: Total Joint ReplacementBibliographyBioactive and Bioresorbable CeramicsLearning ObjectivesOverview of Surface Bioactive and Bulk Degradable CeramicsCalcium Phosphates and HydroxyapatiteBioactive GlassesBioactive Glass-CeramicsBone-Bonding MechanismsBiodegradable CeramicsChapter HighlightsLaboratory Practice 3Simple Questions in ClassProblems and ExercisesAdvanced Topic: Bioceramic Scaffolds for Bone Tissue EngineeringBibliographyPolymeric Biomaterials: FundamentalsLearning ObjectivesBasic Concepts on PolymersOverview of Polymeric BiomaterialsChapter HighlightsActivitiesSimple Questions in ClassProblems and ExercisesAdvanced Topic: Polymers and Polymer Scaffolds for Soft Tissue EngineeringBibliographyBioinert PolymersLearning ObjectivesPolyolefinPoly(Ethylene Terephthalate)Acrylate PolymerFluorocarbon PolymersSiliconePolyurethaneChapter HighlightsActivitiesSimple Questions in ClassProblems and ExercisesAdvanced Topic: Properties and Applications of Polyurethane as BiomaterialsBibliographyBioresorbable PolymersLearning ObjectivesBiodegradation of PolymersPolyesters: PGA, PLA, and PCLPolyesters: PHAElastomeric Polyester: Poly(Polyol Sebacate)Polyether: Poly(Ethylene Glycol)PolyamideSurface-Erodible PolymersBiological PolymersChapter HighlightsSimple Questions in ClassProblems and ExercisesLaboratory Practice 4Advanced Topic: Natural Polymers: Resilin, Silk, and GlutenBibliographyComposite BiomaterialsLearning ObjectivesOverview of CompositesNatural Composites: BoneDental CompositesArtificial BoneChapter HighlightsLaboratory Practice 5Simple Questions in ClassProblems and ExercisesAdvanced Topic: Development of Artificial Bone: Composites and ScaffoldsBibliographyPart IIMedical ScienceMedicine and Medical ScienceLearning ObjectivesMedicine and Medical ScienceMedical Science versus Materials ScienceLearning Goals of Part IIChapter HighlightsActivityBibliographyImage LinksSimple Questions in ClassProblems and ExercisesHuman Anatomy And Diseases I: Integumentary, Skeletal, Muscular, Nervous, and Endocrine SystemsLearning ObjectivesIntegumentary SystemSkeletal SystemMuscular SystemNervous SystemEndocrine SystemChapter HighlightsActivitiesSimple Questions in ClassProblems and ExercisesAdvanced Topic: Biomaterial Challenges in Bone Tissue EngineeringBibliographyHuman Anatomy And Diseases II: Cardiovascular SystemLearning ObjectivesAnatomy and Functions of the Cardiovascular SystemCardiovascular DiseaseCardiac Performance: P-V LoopCurrent Therapies for Heart DiseaseAlternative Treatments and Application of BiomaterialsArtificial Blood VesselsChapter HighlightsActivitiesSimple Questions in ClassProblems and ExercisesBibliographyHuman Anatomy And Diseases III: Respiratory, Lymphatic, Digestive, Urinary, and Reproductive SystemsLearning ObjectivesRespiratory SystemLymphatic SystemDigestive SystemUrinary SystemReproductive SystemChapter HighlightsActivitiesSimple Questions in ClassProblems and ExercisesBibliographyCells and BiomoleculesLearning ObjectivesIntroductionCell Biochemistry and BiosynthesisCell StructureTransport across Plasma MembranesCell ProliferationCell Differentiation and Stem CellsChapter HighlightsActivitiesAdvanced Topic: Cell Therapy to Treat Cardiac DiseaseStrategies to Address Immune Rejection in CellsSummary of Cell-Based Therapies and Their LimitationsSimple Questions in ClassProblems and ExercisesBibliographyHistology and Tissue Properties I: Epithelial, Neuronal, and Muscle TissueLearning ObjectivesIntroductionEpitheliumMuscular TissueNervous TissueChapter HighlightsActivitiesAdvanced Topic: Properties of Proteins in Mammalian TissuesSimple Questions in ClassProblems and ExercisesBibliographyHistology and Tissue Properties II: Connective TissuesLearning ObjectivesOverview of Connective TissuesTypes of Connective TissueConnective Tissue Proper (Skin, Tendon, Ligament)Mechanical Properties of Structural ProteinsCartilageBoneChapter HighlightsLaboratory Practice 6Simple Questions in ClassProblems and ExercisesBibliographyImmune System and Body Responses to BiomaterialsLearning ObjectivesImmune SystemTissue Response to InjuriesBody Response to ImplantsChapter HighlightsActivitiesSimple Questions in ClassProblems and ExercisesBibliographyEvaluation of BiomaterialsLearning ObjectivesOverview of Biomaterials EvaluationStandardsToxicological EvaluationCytotoxicity TestingEvaluation in AnimalsChapter HighlightsLaboratory Practice 7Case Study: Evaluation of Heart Patch in RatsSimple Questions in ClassProblems and ExercisesBibliographyRegulation of Medical DevicesLearning ObjectivesRegulations versus StandardsMedical DevicesPreclinical TestingClinical TrialsDevelopment of Medical Devices and Possible Career OpportunitiesChapter HighlightsActivitiesSimple Questions in ClassProblems and ExercisesBibliographyIndex.…”
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