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703781por Couch, Fergus J., Kuchenbaecker, Karoline B., Michailidou, Kyriaki, Mendoza-Fandino, Gustavo A., Nord, Silje, Lilyquist, Janna, Olswold, Curtis, Hallberg, Emily, Agata, Simona, Ahsan, Habibul, Aittomäki, Kristiina, Ambrosone, Christine, Andrulis, Irene L., Anton-Culver, Hoda, Arndt, Volker, Arun, Banu K., Arver, Brita, Barile, Monica, Barkardottir, Rosa B., Barrowdale, Daniel, Beckmann, Lars, Beckmann, Matthias W., Benitez, Javier, Blank, Stephanie V., Blomqvist, Carl, Bogdanova, Natalia V., Bojesen, Stig E., Bolla, Manjeet K., Bonanni, Bernardo, Brauch, Hiltrud, Brenner, Hermann, Burwinkel, Barbara, Buys, Saundra S., Caldes, Trinidad, Caligo, Maria A., Canzian, Federico, Carpenter, Jane, Chang-Claude, Jenny, Chanock, Stephen J., Chung, Wendy K., Claes, Kathleen B. M., Cox, Angela, Cross, Simon S., Cunningham, Julie M., Czene, Kamila, Daly, Mary B., Damiola, Francesca, Darabi, Hatef, de la Hoya, Miguel, Devilee, Peter, Diez, Orland, Ding, Yuan C., Dolcetti, Riccardo, Domchek, Susan M., Dorfling, Cecilia M., dos-Santos-Silva, Isabel, Dumont, Martine, Dunning, Alison M., Eccles, Diana M., Ehrencrona, Hans, Ekici, Arif B., Eliassen, Heather, Ellis, Steve, Fasching, Peter A., Figueroa, Jonine, Flesch-Janys, Dieter, Försti, Asta, Fostira, Florentia, Foulkes, William D., Friebel, Tara, Friedman, Eitan, Frost, Debra, Gabrielson, Marike, Gammon, Marilie D., Ganz, Patricia A., Gapstur, Susan M., Garber, Judy, Gaudet, Mia M., Gayther, Simon A., Gerdes, Anne-Marie, Ghoussaini, Maya, Giles, Graham G., Glendon, Gord, Godwin, Andrew K., Goldberg, Mark S., Goldgar, David E., González-Neira, Anna, Greene, Mark H., Gronwald, Jacek, Guénel, Pascal, Gunter, Marc, Haeberle, Lothar, Haiman, Christopher A., Hamann, Ute, Hansen, Thomas V. O., Hart, Steven, Healey, Sue, Heikkinen, Tuomas, Henderson, Brian E., Herzog, Josef, Hogervorst, Frans B. L., Hollestelle, Antoinette, Hooning, Maartje J., Hoover, Robert N., Hopper, John L., Humphreys, Keith, Hunter, David J., Huzarski, Tomasz, Imyanitov, Evgeny N., Isaacs, Claudine, Jakubowska, Anna, James, Paul, Janavicius, Ramunas, Jensen, Uffe Birk, John, Esther M., Jones, Michael, Kabisch, Maria, Kar, Siddhartha, Karlan, Beth Y., Khan, Sofia, Khaw, Kay-Tee, Kibriya, Muhammad G., Knight, Julia A., Ko, Yon-Dschun, Konstantopoulou, Irene, Kosma, Veli-Matti, Kristensen, Vessela, Kwong, Ava, Laitman, Yael, Lambrechts, Diether, Lazaro, Conxi, Lee, Eunjung, Le Marchand, Loic, Lester, Jenny, Lindblom, Annika, Lindor, Noralane, Lindstrom, Sara, Liu, Jianjun, Long, Jirong, Lubinski, Jan, Mai, Phuong L., Makalic, Enes, Malone, Kathleen E., Mannermaa, Arto, Manoukian, Siranoush, Margolin, Sara, Marme, Frederik, Martens, John W. M., McGuffog, Lesley, Meindl, Alfons, Miller, Austin, Milne, Roger L., Miron, Penelope, Montagna, Marco, Mazoyer, Sylvie, Mulligan, Anna M., Muranen, Taru A., Nathanson, Katherine L., Neuhausen, Susan L., Nevanlinna, Heli, Nordestgaard, Børge G., Nussbaum, Robert L., Offit, Kenneth, Olah, Edith, Olopade, Olufunmilayo I., Olson, Janet E., Osorio, Ana, Park, Sue K., Peeters, Petra H., Peissel, Bernard, Peterlongo, Paolo, Peto, Julian, Phelan, Catherine M., Pilarski, Robert, Poppe, Bruce, Pylkäs, Katri, Radice, Paolo, Rahman, Nazneen, Rantala, Johanna, Rappaport, Christine, Rennert, Gad, Richardson, Andrea, Robson, Mark, Romieu, Isabelle, Rudolph, Anja, Rutgers, Emiel J., Sanchez, Maria-Jose, Santella, Regina M., Sawyer, Elinor J., Schmidt, Daniel F., Schmidt, Marjanka K., Schmutzler, Rita K., Schumacher, Fredrick, Scott, Rodney, Senter, Leigha, Sharma, Priyanka, Simard, Jacques, Singer, Christian F., Sinilnikova, Olga M., Soucy, Penny, Southey, Melissa, Steinemann, Doris, Stenmark-Askmalm, Marie, Stoppa-Lyonnet, Dominique, Swerdlow, Anthony, Szabo, Csilla I., Tamimi, Rulla, Tapper, William, Teixeira, Manuel R., Teo, Soo-Hwang, Terry, Mary B., Thomassen, Mads, Thompson, Deborah, Tihomirova, Laima, Toland, Amanda E., Tollenaar, Robert A. E. M., Tomlinson, Ian, Truong, Thérèse, Tsimiklis, Helen, Teulé, Alex, Tumino, Rosario, Tung, Nadine, Turnbull, Clare, Ursin, Giski, van Deurzen, Carolien H. M., van Rensburg, Elizabeth J., Varon-Mateeva, Raymonda, Wang, Zhaoming, Wang-Gohrke, Shan, Weiderpass, Elisabete, Weitzel, Jeffrey N., Whittemore, Alice, Wildiers, Hans, Winqvist, Robert, Yang, Xiaohong R., Yannoukakos, Drakoulis, Yao, Song, Zamora, M Pilar, Zheng, Wei, Hall, Per, Kraft, Peter, Vachon, Celine, Slager, Susan, Chenevix-Trench, Georgia, Pharoah, Paul D. P., Monteiro, Alvaro A. N., García-Closas, Montserrat, Easton, Douglas F., Antoniou, Antonis C.Enlace del recurso
Publicado 2016
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703782por Theron, Grant, Peter, Jonny, Richardson, Marty, Warren, Rob, Dheda, Keertan, Steingart, Karen R“…We had insufficient data to estimate summary sensitivity and specificity of version 2.0 (smear‐positive and ‐negative specimens) or to compare accuracy of the two versions. A limitation was that most included studies did not consistently use the World Health Organization (WHO)‐recommended concentrations for drugs in the culture‐based DST reference standard. …”
Publicado 2016
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703783por Baio, Jon, Wiggins, Lisa, Christensen, Deborah L., Maenner, Matthew J, Daniels, Julie, Warren, Zachary, Kurzius-Spencer, Margaret, Zahorodny, Walter, Robinson Rosenberg, Cordelia, White, Tiffany, Durkin, Maureen S., Imm, Pamela, Nikolaou, Loizos, Yeargin-Allsopp, Marshalyn, Lee, Li-Ching, Harrington, Rebecca, Lopez, Maya, Fitzgerald, Robert T., Hewitt, Amy, Pettygrove, Sydney, Constantino, John N., Vehorn, Alison, Shenouda, Josephine, Hall-Lande, Jennifer, Van Naarden Braun, Kim, Dowling, Nicole F.“…Although the DSM-IV-TR case definition will eventually be phased out, it will be applied in a limited geographic area to offer additional data for comparison. …”
Publicado 2018
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703784“…Poor reporting is a major limitation. 2 April 2019 Up to date All studies incorporated from most recent search All eligible published studies found in the last search (25 Apr, 2017) were included and one ongoing study was identified (see 'Characteristics of ongoing studies' section)…”
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703785por Chen, Yifan, Wang, Zhenyu, Ding, Jian, Ming, Dongxu, Wang, Wenhui, Jiang, Zhaoning, Liu, Ling, Wang, Fenglai“…There are some reports of determining the ELF using regression methods based on different levels of fat intake, while reports on effects of dietary fiber content and different fiber-rich ingredients in pig diets on ELF are very limited. Therefore, the objective of this study was to determine the effects of dietary fiber content and different fiber-rich ingredients on endogenous losses of fat and fatty acids at the end of ileum and throughout the entire intestinal tract in growing pigs. …”
Publicado 2019
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703786por Weisenthal, Samuel, Weisenthal, Samuel J., Quill, Caroline, Luo, Jiebo, Kautz, Henry, Farooq, Samir, Zand, Martin“…The authors recognize several limitations. Since our data set corresponds to a time-window sample, patients with high frequency of hospital utilization are likely overrepresented. …”
Publicado 2018
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703787por Cappello, Carmelina, Cuming, Tamzin, Bowring, Julie, Rosenthal, Adam N., Chindawi, Noreen, Nathan, Mayura“…There were no metastases, abdominoperineal excisions, or deaths from anal squamous cell carcinoma. LIMITATIONS: Retrospective data were used for this study. …”
Publicado 2020
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703788por Xia, Shengli, Zhang, Yuntao, Wang, Yanxia, Wang, Hui, Yang, Yunkai, Gao, George Fu, Tan, Wenjie, Wu, Guizhen, Xu, Miao, Lou, Zhiyong, Huang, Weijin, Xu, Wenbo, Huang, Baoying, Wang, Huijuan, Wang, Wei, Zhang, Wei, Li, Na, Xie, Zhiqiang, Ding, Ling, You, Wangyang, Zhao, Yuxiu, Yang, Xuqin, Liu, Yang, Wang, Qian, Huang, Lili, Yang, Yongli, Xu, Guangxue, Luo, Bojian, Wang, Wenling, Liu, Peipei, Guo, Wanshen, Yang, Xiaoming“…One placebo recipient in the 4 μg days 0 and 21 group reported grade 3 fever, but was self-limited and recovered. All other adverse reactions were mild or moderate in severity. …”
Publicado 2021
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703789por Seidel, Danila, Cornely, Oliver, Vehreschild, Maria J G T, Koehler, Philipp, Salmanton-García, Jon, Klimko, Nikolay, Herbrecht, Raoul, Heinemann, Melina, Prattes, Jürgen, Schalk, Enrico, Miceli, Marisa H, Ráčil, Zdeněk, Falces-Romero, Iker, Hoenigl, Martin, Kessel, Johanna, Bertz, Hartmut, Novak, Jan, Wisplinghoff, Hilmar, Barmaki-Rad, Farima, Saulay, Mikael, Engelhardt, Marc, Hamed, Kamal“…DISCLOSURES: Danila Seidel, PhD, Basilea (Other Financial or Material Support, travel grant) Oliver Cornely, Prof., Actelion (Grant/Research Support)Actelion (Other Financial or Material Support, Personal fees)Al Jazeera Pharmaceuticals (Consultant)Allecra Therapeutics (Other Financial or Material Support, Personal fees)Amplyx (Other Financial or Material Support, Personal fees)Amplyx (Grant/Research Support)Astellas (Grant/Research Support)Astellas (Other Financial or Material Support, Personal fees)Basilea (Other Financial or Material Support, Personal fees)Basilea (Grant/Research Support)Biosys UK Limited (Other Financial or Material Support, Personal fees)Cidara (Other Financial or Material Support, Personal fees)Cidara (Grant/Research Support)Da Volterra (Grant/Research Support)Da Volterra (Other Financial or Material Support, Personal fees)Entasis (Other Financial or Material Support, Personal fees)F2G (Other Financial or Material Support)F2G (Grant/Research Support)Gilead (Grant/Research Support)Gilead (Other Financial or Material Support, Personal fees)Grupo Biotoscana (Other Financial or Material Support, Personal fees)Janssen Pharmaceuticals (Grant/Research Support)Matinas (Other Financial or Material Support, Personal fees)Medicines Company (Grant/Research Support)MedPace (Grant/Research Support)MedPace (Other Financial or Material Support, Personal fees)Melinta Therapeutics (Grant/Research Support)Menarini Ricerche (Other Financial or Material Support, Personal fees)Merck/MSD (Other Financial or Material Support, Personal fees)Merck/MSD (Grant/Research Support)Mylan Pharmaceuticals (Consultant)Nabriva Therapeutics (Other Financial or Material Support, Personal fees)Octapharma (Other Financial or Material Support, Personal fees)Paratek Pharmaceuticals (Other Financial or Material Support, Personal fees)Pfizer (Other Financial or Material Support, Personal fees)Pfizer (Grant/Research Support)PSI (Other Financial or Material Support, Personal fees)Rempex (Other Financial or Material Support, Personal fees)Roche Diagnostics (Other Financial or Material Support, Personal fees)Scynexis (Other Financial or Material Support, Personal fees)Scynexis (Grant/Research Support)Seres Therapeutics (Other Financial or Material Support, Personal fees)Tetraphase (Other Financial or Material Support, Personal fees) Philipp Koehler, MD, Akademie für Infektionsmedizin e.V., (Other Financial or Material Support, Personal fees)Astellas Pharma GmbH (Other Financial or Material Support, Personal fees)Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases, University of Cologne, Cologne, Germany (Other Financial or Material Support, Other)Gilead Sciences GmbH (Other Financial or Material Support, Personal fees)GPR Academy Ruesselsheim (Speaker’s Bureau)Miltenyi Biotec GmbH (Other Financial or Material Support, Non-financial support)MSD Sharp & Dohme GmbH (Other Financial or Material Support, Personal fees)Noxxon N.V. …”
Publicado 2020
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703790por Stegeman, Inge, Ochodo, Eleanor A, Guleid, Fatuma, Holtman, Gea A., Yang, Bada, Davenport, Clare, Deeks, Jonathan J, Dinnes, Jacqueline, Dittrich, Sabine, Emperador, Devy, Hooft, Lotty, Spijker, René, Takwoingi, Yemisi, Van den Bruel, Ann, Wang, Junfeng, Langendam, Miranda, Verbakel, Jan Y, Leeflang, Mariska MG“…These laboratory tests may be useful for the triage of people with potential COVID‐19 to prioritize them for different levels of treatment, especially in situations where time and resources are limited. OBJECTIVES: To assess the diagnostic accuracy of routine laboratory testing as a triage test to determine if a person has COVID‐19. …”
Publicado 2020
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703791Tocilizumab au cours du COVID-19 : le plus tôt serait le mieux ? Une analyse exploratoire de cohortepor Jachiet, V., Richier, Q., Carrat, F., Abisror, N., Dhôte, R., Jerome, P., Marc, G., Maurier, F., Olivier, H., Michel, M., Godeau, B., Boris, B., Cloé, C., Cacoub, P., Mahévas, T., Chasset, F., Adedjouma, A., Fain, O., Lacombe, K., Mekinian, A.“…Les critères d’exclusion étaient une contre-indication au TCZ, une hospitalisation en soins intensifs avant ou dans les 24 heures après TCZ ou une limitation thérapeutique. Les facteurs de risque de mortalité au cours de l’infection au COVID-19 modérée ou sévère après TCZ ont été analysés selon des modèles multivariés de régression logistique et de Cox. …”
Publicado 2021
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703792por Giacomini, E, Scotti, G M, Vanni, V S, Lazarevic, D, Makieva, S, Privitera, L, Signorelli, S, Cantone, L, Bollati, V, Murdica, V, Tonon, G, Papaleo, E, Candiani, M, Viganò, P“…LARGE SCALE DATA: Transcriptomic data were deposited in NCBI Gene Expression Omnibus (GEO) and can be retrieved using GEO series accession number: GSE158958. LIMITATIONS, REASONS FOR CAUTION: Separation of RNA species associated with EV membranes might have been incomplete, and membrane-bound RNA species—rather than the internal RNA content of EVs—might have contributed to our RNA-seq results. …”
Publicado 2021
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703793por Demichelis, Roberta, Alvarado, Martha, Vasquez, Jule F, Delgado, Nancy, Gómez, Cynthia, Espinosa, Karla Adriana, Cooke, Ana, Milan, Andrea, Gomez-De Leon, Andres, Yu Ling, Lee-Tsai, Rosales, Daniel Estuardo, Cabrero Garcia, Alvaro, Amador, Lauro Fabian, Córdova-Ramírez, Carmina Alejandra, Murrieta-Álvarez, Iván, Solís-Poblano, Juan Carlos, Apodaca, Elia Ixel, Rangel-Patiño, Juan, Álvarez, Jose Luis, Arana, Luara, De la Peña-Celaya, Jose Antonio, Espitia, María Eugenia, Hernandez, Eleazar, Perez, Juan Manuel, González-Rivera, Rosa, García-Leyva, María Fernanda, Peña, Estefania, Tejeda Romero, Monica, Balderas-Delgado, Carolina, Cruz Rico, Jorge, Ruiz Arguelles, Guillermo, Gomez-Almaguer, David“…However, multiple logistical issues tangentially associated with the pandemic have also appeared, potentially limiting the quality of management of these patients. …”
Publicado 2020
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703794por Wood, William A., Neuberg, Donna S., Thompson, John Colton, Tallman, Martin S., Sekeres, Mikkael A., Sehn, Laurie H., Anderson, Kenneth, Goldberg, Aaron D, Pennell, Nathan A, Niemeyer, Charlotte M., Tucker, Emily, Hewitt, Kathleen, Plovnick, Robert M, Hicks, Lisa K.“…Data presented here are limited to malignant hematologic diseases only. Contributors are individual providers or designees submitting data on behalf of providers. …”
Publicado 2020
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703795por Melbye, Silje Marie, Haug, Sofie Cecilia Dietrich, Fenstad, Anne Marie, Furnes, Ove, Gjertsen, Jan-Erik, Hallan, Geir“…The proportion of patients who died was limited, and there was no difference in death rate between the groups compared. …”
Publicado 2021
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703796por Crickx, E., Moulis, G., Ebbo, M., Audia, S., Comont, T., Terriou, L., Bonnotte, B., Dion, J., Briantais, A., Languille, L., Limal, N., Guillet, S., Michel, M., Mahevas, M., Godeau, B.“…Les données cliniques et biologiques étaient recueillies avec un formulaire standardisé, et le suivi était limité à 3 mois après la première injection vaccinale. …”
Publicado 2021
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703797por Tohidi-Esfahani, Ibrahim, Warden, Andrew, Malunis, Elena, deNardis, Peter Liburdi, Postek, Michelle, D'Sa, Shirley, Kersten, Marie José, Thomas, Sheeba K, Palomba, M. Lia, Olszewski, Adam J., Guerin, Newton, Scott, Clare, Trotman, Judith“…Comparison of TTNT was limited to the four most common first-line therapies: BR, Rit., DRC, with zanubrutinib (n=5) and ibrutinib plus rituximab (n=2) adding to the first line Bruton tyrosine Kinase inhibitor (BTKi) cohort (n=32). …”
Publicado 2021
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703798por Molica, Stefano, Laurenti, Luca, Ghia, Paolo, Coscia, Marta, Cuneo, Antonio, Gaidano, Gianluca, Mauro, Francesca, Frustaci, Anna Maria, Vallisa, Daniele, Pane, Fabrizio, Gualberti, Giuliana, Iannella, Emilia, Finsinger, Paola, Caira, Morena, Sportoletti, Paolo“…In contrast to previously published DCEs (1-2), where PFS was the most important attribute, in the CHOICE study pts put much more emphasis on their concerns about possible infections: this could be due to the influence of the 1 (st) Covid-19 pandemic wave, with the relevant feeling of uncertainty, also due to the great attention that media has dedicated to the issue of infection in general, especially for vulnerable individuals such as CLL pts. The limitation in hospital access during the 1 (st) wave and the overall need of personal protection (masks usage) and social distancing might have influenced patients' responses too. …”
Publicado 2021
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703799por Averbuch, Diana, De La Camara, Rafael, Corbacioglu, Selim, Mikulska, Malgorzata, Piñana Sanchez, Jose Luis, Tridello, Gloria, Knelange, Nina Simone, Kulagin, Aleksandr D., Ayas, Mouhab, Perez-Martinez, Antonio, Hamidieh, Amir Ali, Sundin, Mikael, Martino, Rodrigo, Sedlacek, Petr, Cesaro, Simone, Paillard, Catherine, Gibson, Brenda, Lawson, Sarah, Kroeger, Nicolaus, Styczynski, Jan, Ljungman, Per“…Data on its course in children following hematopoietic cell transplantation (HCT) is limited. Methods Data on children following HCT who developed COVID-19 (diagnosed by positive SARS-CoV-2 PCR on respiratory tract samples) during 3.2020-4.2021 were prospectively collected by EBMT and GETH, including demography, HCT data, COVID-related manifestations, ICU admission and mortality. …”
Publicado 2021
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703800por Gladstone, Douglas E, Howard, Christopher, Lyu, Mi-Ae, Mock, Jason, Adams, Darryl, Gibbs, Kevin, Li, Li, Huang, Meixian, Zeng, Ke, D'Alessio, Franco, Herlihy, James, Trevino, Sergio, Hari, Parameswaran, Sadeghi, Tara, Parmar, Simrit, Slutsky, Arthur, Mukherjee, Siddhartha“…Primary Outcomes. • Dose Limiting Toxicity (DLT) = Regimen related grade 3, 4, or 5 toxicity within 48 hours of first infusion; • S28 = [Alive and not intubated 28 days after the date of first infusion] = 28-day treatment success. …”
Publicado 2021
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