-
1561“…She was admitted to Daisy Hill Hospital in Newry, Northern Ireland on 22/3/19 with pyrexia, right sided abdominal pain and leucopenia. …”
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
1562por Kuan, Valerie, Denaxas, Spiros, Gonzalez-Izquierdo, Arturo, Direk, Kenan, Bhatti, Osman, Husain, Shanaz, Sutaria, Shailen, Hingorani, Melanie, Nitsch, Dorothea, Parisinos, Constantinos A, Lumbers, R Thomas, Mathur, Rohini, Sofat, Reecha, Casas, Juan P, Wong, Ian C K, Hemingway, Harry, Hingorani, Aroon D“…FUNDING: Wellcome Trust, National Institute for Health Research, Medical Research Council, Arthritis Research UK, British Heart Foundation, Cancer Research UK, Chief Scientist Office of the Scottish Government Health and Social Care Directorates, Department of Health and Social Care (England), Health and Social Care Research and Development Division (Welsh Government), Public Health Agency (Northern Ireland), Economic and Social Research Council, Engineering and Physical Sciences Research Council, National Institute for Social Care and Health Research, and The Alan Turing Institute.…”
Publicado 2019
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
1563por Kalsi, Jatinderpal K., Ryan, Andy, Gentry-Maharaj, Aleksandra, Margolin-Crump, Danielle, Singh, Naveena, Burnell, Matthew, Benjamin, Elizabeth, Apostolidou, Sophia, Habib, Mariam, Massingham, Susan, Karpinskyj, Chloe, Woolas, Robert, Widschwendter, Martin, Fallowfield, Lesley, Campbell, Stuart, Skates, Steven, McGuire, Alistair, Parmar, Max, Jacobs, Ian, Menon, Usha“…METHODS: Of the 202,638 participants, 202,632 were successfully linked and followed through national cancer and death registries of Northern Ireland, Wales and England. Women with registrations of any of 19 pre-defined ICD-10 codes suggestive of tubo-ovarian cancer or notification of ovarian/tubal/peritoneal cancer from hospital episode statistics or trial sites were identified. …”
Publicado 2021
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
1564por Brennan, Sarah F., Lavelle, Fiona, Moore, Sarah E., Dean, Moira, McKinley, Michelle C., McCole, Patrick, Hunter, Ruth F., Dunne, Laura, O’Connell, Niamh E., Cardwell, Chris R., Elliott, Chris T., McCarthy, Danielle, Woodside, Jayne V.“…Primary schools in Northern Ireland were randomised to one of four 6-month intervention arms: i) ‘Nourish’, ii) ‘Engage’, iii) ‘Nourish’ and ‘Engage’ and iv) Control (Delayed). …”
Publicado 2021
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
1565por Menon, Usha, Gentry-Maharaj, Aleksandra, Burnell, Matthew, Singh, Naveena, Ryan, Andy, Karpinskyj, Chloe, Carlino, Giulia, Taylor, Julie, Massingham, Susan K, Raikou, Maria, Kalsi, Jatinderpal K, Woolas, Robert, Manchanda, Ranjit, Arora, Rupali, Casey, Laura, Dawnay, Anne, Dobbs, Stephen, Leeson, Simon, Mould, Tim, Seif, Mourad W, Sharma, Aarti, Williamson, Karin, Liu, Yiling, Fallowfield, Lesley, McGuire, Alistair J, Campbell, Stuart, Skates, Steven J, Jacobs, Ian J, Parmar, Mahesh“…METHODS: In this randomised controlled trial, postmenopausal women aged 50–74 years were recruited from 13 centres in National Health Service trusts in England, Wales, and Northern Ireland. Exclusion criteria were bilateral oophorectomy, previous ovarian or active non-ovarian malignancy, or increased familial ovarian cancer risk. …”
Publicado 2021
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
1566por Cabezas-Garcia, Edward H., Gordon, Alan W., Mulligan, Finbar J., Ferris, Conrad P.“…The data were collected from 27 long-term production trials conducted between 1996 and 2016 at the Agri-Food and Biosciences Institute (AFBI) in Hillsborough, Northern Ireland. In total, 1321 lactations (1 to 20 weeks in milk; WIM), derived from 840 individual cows fed mainly grass silage-based diets, were included in the analysis. …”
Publicado 2021
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
1567por Lee, Siang Ing, Azcoaga-Lorenzo, Amaya, Agrawal, Utkarsh, Kennedy, Jonathan I., Fagbamigbe, Adeniyi Francis, Hope, Holly, Subramanian, Anuradhaa, Anand, Astha, Taylor, Beck, Nelson-Piercy, Catherine, Damase-Michel, Christine, Yau, Christopher, Crowe, Francesca, Santorelli, Gillian, Eastwood, Kelly-Ann, Vowles, Zoe, Loane, Maria, Moss, Ngawai, Brocklehurst, Peter, Plachcinski, Rachel, Thangaratinam, Shakila, Black, Mairead, O’Reilly, Dermot, Abel, Kathryn M., Brophy, Sinead, Nirantharakumar, Krishnarajah, McCowan, Colin“…This study aims to estimate the prevalence of pre-existing multimorbidity (two or more long-term physical or mental health conditions) in pregnant women in the United Kingdom (England, Northern Ireland, Wales and Scotland). STUDY DESIGN: Pregnant women aged 15–49 years with a conception date 1/1/2018 to 31/12/2018 were included in this population-based cross-sectional study, using routine healthcare datasets from primary care: Clinical Practice Research Datalink (CPRD, United Kingdom, n = 37,641) and Secure Anonymized Information Linkage databank (SAIL, Wales, n = 27,782), and secondary care: Scottish Morbidity Records with linked community prescribing data (SMR, Tayside and Fife, n = 6099). …”
Publicado 2022
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
1568por Rankin, Audrey, Gorman, Ashleigh, Cole, Judith, Cadogan, Cathal A., Barry, Heather E., Agus, Ashley, Logan, Danielle, McDowell, Cliona, Molloy, Gerard J., Ryan, Cristín, Leathem, Claire, Maxwell, Marina, Brennan, Connie, Gormley, Gerard J., Ferrett, Alan, McCarthy, Pat, Fahey, Tom, Hughes, Carmel M.“…This pilot study aims to assess the feasibility of the PolyPrime intervention in primary care in Northern Ireland (NI) and the Republic of Ireland (ROI). …”
Publicado 2022
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
1569por Steel, Nicholas, Ford, John A, Newton, John N, Davis, Adrian C J, Vos, Theo, Naghavi, Mohsen, Glenn, Scott, Hughes, Andrew, Dalton, Alice M, Stockton, Diane, Humphreys, Ciaran, Dallat, Mary, Schmidt, Jürgen, Flowers, Julian, Fox, Sebastian, Abubakar, Ibrahim, Aldridge, Robert W, Baker, Allan, Brayne, Carol, Brugha, Traolach, Capewell, Simon, Car, Josip, Cooper, Cyrus, Ezzati, Majid, Fitzpatrick, Justine, Greaves, Felix, Hay, Roderick, Hay, Simon, Kee, Frank, Larson, Heidi J, Lyons, Ronan A, Majeed, Azeem, McKee, Martin, Rawaf, Salman, Rutter, Harry, Saxena, Sonia, Sheikh, Aziz, Smeeth, Liam, Viner, Russell M, Vollset, Stein Emil, Williams, Hywel C, Wolfe, Charles, Woolf, Anthony, Murray, Christopher J L“…METHODS: We extracted data from the GBD 2016 to estimate years of life lost (YLLs), years lived with disability (YLDs), disability-adjusted life-years (DALYs), and attributable risks from 1990 to 2016 for England, Scotland, Wales, Northern Ireland, the UK, and 150 English Upper-Tier Local Authorities. …”
Publicado 2018
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
1570por Hellyer, Thomas P, McAuley, Daniel F, Walsh, Timothy S, Anderson, Niall, Conway Morris, Andrew, Singh, Suveer, Dark, Paul, Roy, Alistair I, Perkins, Gavin D, McMullan, Ronan, Emerson, Lydia M, Blackwood, Bronagh, Wright, Stephen E, Kefala, Kallirroi, O'Kane, Cecilia M, Baudouin, Simon V, Paterson, Ross L, Rostron, Anthony J, Agus, Ashley, Bannard-Smith, Jonathan, Robin, Nicole M, Welters, Ingeborg D, Bassford, Christopher, Yates, Bryan, Spencer, Craig, Laha, Shondipon K, Hulme, Jonathan, Bonner, Stephen, Linnett, Vanessa, Sonksen, Julian, Van Den Broeck, Tina, Boschman, Gert, Keenan, DW James, Scott, Jonathan, Allen, A Joy, Phair, Glenn, Parker, Jennie, Bowett, Susan A, Simpson, A John“…METHODS: VAPrapid2 was a multicentre, randomised controlled trial in patients admitted to 24 ICUs from 17 National Health Service hospital trusts across England, Scotland, and Northern Ireland. Patients were screened for eligibility and included if they were 18 years or older, intubated and mechanically ventilated for at least 48 h, and had suspected ventilator-associated pneumonia. …”
Publicado 2020
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
1571por Heaney, Liam G, Busby, John, Hanratty, Catherine E, Djukanovic, Ratko, Woodcock, Ashley, Walker, Samantha M, Hardman, Timothy C, Arron, Joseph R, Choy, David F, Bradding, Peter, Brightling, Christopher E, Chaudhuri, Rekha, Cowan, Douglas C, Mansur, Adel H, Fowler, Stephen J, Niven, Robert M, Howarth, Peter H, Lordan, James L, Menzies-Gow, Andrew, Harrison, Tim W, Robinson, Douglas S, Holweg, Cecile T J, Matthews, John G, Pavord, Ian D“…METHODS: We did a single-blind, parallel group, randomised controlled trial in adults (18–80 years of age) with severe asthma (at treatment steps 4 and 5 of the Global Initiative for Asthma) and FENO of less than 45 parts per billion at 12 specialist severe asthma centres across England, Scotland, and Northern Ireland. Patients were randomly assigned (4:1) to either the biomarker strategy group or the control group by an online electronic case-report form, in blocks of ten, stratified by asthma control and use of rescue systemic steroids in the previous year. …”
Publicado 2021
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
1572por Hunter, Ruth F., Adlakha, Deepti, Cardwell, Christopher, Cupples, Margaret E., Donnelly, Michael, Ellis, Geraint, Gough, Aisling, Hutchinson, George, Kearney, Therese, Longo, Alberto, Prior, Lindsay, McAneney, Helen, Ferguson, Sara, Johnston, Brian, Stevenson, Michael, Kee, Frank, Tully, Mark A.“…The development of an urban greenway (9 km running along 3 rivers) in Northern Ireland provided the opportunity to conduct a natural experiment. …”
Publicado 2021
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
1573por Jacobs, Ian J, Menon, Usha, Ryan, Andy, Gentry-Maharaj, Aleksandra, Burnell, Matthew, Kalsi, Jatinderpal K, Amso, Nazar N, Apostolidou, Sophia, Benjamin, Elizabeth, Cruickshank, Derek, Crump, Danielle N, Davies, Susan K, Dawnay, Anne, Dobbs, Stephen, Fletcher, Gwendolen, Ford, Jeremy, Godfrey, Keith, Gunu, Richard, Habib, Mariam, Hallett, Rachel, Herod, Jonathan, Jenkins, Howard, Karpinskyj, Chloe, Leeson, Simon, Lewis, Sara J, Liston, William R, Lopes, Alberto, Mould, Tim, Murdoch, John, Oram, David, Rabideau, Dustin J, Reynolds, Karina, Scott, Ian, Seif, Mourad W, Sharma, Aarti, Singh, Naveena, Taylor, Julie, Warburton, Fiona, Widschwendter, Martin, Williamson, Karin, Woolas, Robert, Fallowfield, Lesley, McGuire, Alistair J, Campbell, Stuart, Parmar, Mahesh, Skates, Steven J“…METHODS: In this randomised controlled trial, we recruited postmenopausal women aged 50–74 years from 13 centres in National Health Service Trusts in England, Wales, and Northern Ireland. Exclusion criteria were previous bilateral oophorectomy or ovarian malignancy, increased risk of familial ovarian cancer, and active non-ovarian malignancy. …”
Publicado 2016
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
1574por Kirwan, Collette, Hynes, Lisa, Hart, Nigel, Mulligan, Sarah, Leathem, Claire, McQuillan, Laura, Maxwell, Marina, Carr, Emma, Roche, Kevin, Walkin, Scott, McCarthy, Caroline, Bradley, Colin, Byrne, Molly, Smith, Susan M., Hughes, Carmel, Corry, Maura, Kearney, Patricia M., McCarthy, Geraldine, Cupples, Margaret, Gillespie, Paddy, Hobbins, Anna, Newell, John, Glynn, Liam, Roshan, Davood, Sinnott, Carol, Murphy, Andrew W.“…AIM: The pilot study aimed to assess the feasibility of a definitive trial of the MyComrade intervention across two healthcare systems (Republic of Ireland (ROI) and Northern Ireland (NI)). DESIGN: A pilot cluster-randomised controlled trial was conducted (clustered at general practice level), using specific progression criteria and a process evaluation framework. …”
Publicado 2022
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
1575por Perkins, Gavin D., Couper, Keith, Connolly, Bronwen, Baillie, J. Kenneth, Bradley, Judy M., Dark, Paul, De Soyza, Anthony, Gorman, Ellen, Gray, Alasdair, Hamilton, Louisa, Hart, Nicholas, Ji, Chen, Lall, Ranjit, McGowan, Nicola, Regan, Scott, Simonds, Anita K., Skilton, Emma, Stallard, Nigel, Stimpson, Emily, Yeung, Joyce, McAuley, Daniel F.“…PARTICIPANTS: The trial is being conducted across approximately 60 hospitals across England, Wales, Scotland, and Northern Ireland. Inpatients at participating hospitals are eligible to participate if they have respiratory failure with suspected or proven COVID-19, and meet all of the inclusion criteria and none of the exclusion criteria. …”
Publicado 2020
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
1576por Wilkinson, Tom, Dixon, Rupert, Page, Clive, Carroll, Miles, Griffiths, Gareth, Ho, Ling-Pei, De Soyza, Anthony, Felton, Timothy, Lewis, Keir E., Phekoo, Karen, Chalmers, James D., Gordon, Anthony, McGarvey, Lorcan, Doherty, Jillian, Read, Robert C., Shankar-Hari, Manu, Martinez-Alier, Nuria, O’Kelly, Michael, Duncan, Graeme, Walles, Roelize, Sykes, James, Summers, Charlotte, Singh, Dave“…Participants will be recruited from England, Northern Ireland, Wales and Scotland. INTERVENTION AND COMPARATOR: Comparator is current standard of care (SoC) for the treatment of COVID-19. …”
Publicado 2020
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
1577por Halford, Sarah, Wan, Susan, Dragoni, Ilaria, Silvester, Julie, Nazarov, Bobojon, Anthony, Daniel, Anthony, Suzie, Ladds, Emma, Norrie, John, Dhaliwal, Kevin“…A formal interim analysis will be performed once 50% of the maximum sample size has been recruited PARTICIPANTS: The trial will recruit adults (≥ 18 years) who score moderate to very high risk according to COVID-age risk calculation, with typical symptoms of COVID-19 infection as per Public Health England guidance or equivalent organisations in the UK, Health Protection Scotland, Public Health Wales, Public Health Agency (Northern Ireland) and with evidence of current COVID-19 infection from a validated assay. …”
Publicado 2021
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
1578por Maheshwari, Abha, Bell, Jennifer L, Bhide, Priya, Brison, Daniel, Child, Tim, Chong, Huey Yi, Cheong, Ying, Cole, Christina, Coomarasamy, Arri, Cutting, Rachel, Hardy, Pollyanna, Hamoda, Haitham, Juszczak, Edmund, Khalaf, Yacoub, Kurinczuk, Jennifer J, Lavery, Stuart, Linsell, Louise, Macklon, Nick, Mathur, Raj, Pundir, Jyotsna, Raine-Fenning, Nick, Rajkohwa, Madhurima, Scotland, Graham, Stanbury, Kayleigh, Troup, Stephen, Bhattacharya, Siladitya“…E.J. reports membership of the NHS England and NIHR Partnership Programme, membership of five Data Monitoring Committees (Chair of two), membership of six Trial Steering Committees (Chair of four), membership of the Northern Ireland Clinical Trials Unit Advisory Group and Chair of the board of Oxford Brain Health Clinical Trials Unit. …”
Publicado 2022
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto