“…The miRNA-target gene pairs in the FH group are over-represented for MAPK, ErbB, HIF-1, FoxO, p53, mTOR, T-cell receptor, insulin and GnRH signaling pathways, while those in the SFH group include cell cycle, p53 signaling pathway and apoptosis. …”
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“…Compared to conventional ventilation, with closed-loop ventilation the median transpulmonary ΔP with was lower (7.0 [5.0–10.0] vs. 10.0 [8.0–11.0] cmH(2)O, mean difference − 2.5 [95% CI − 2.6 to − 2.1] cmH(2)O; P = 0.0001). Inspiratory transpulmonary pressure and the respiratory rate were also lower. …”
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“…Bourdeau: None. Background: Mitotane (o,p’DDD) is an adrenolytic steroidogenesis inhibitor recommended in the treatment of adrenocortical carcinoma (ACC) with a high risk of recurrence. …”
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“…Respiratory effort was significantly lower with HFNC than with standard oxygen therapy, as evidenced by esophageal pressure swings (5.3 [4.2–7.1] vs. 7.2 [5.6–10.3] cmH(2)O; p < 0.001), pressure–time product (85 [67–140] vs. 156 [114–238] cmH(2)O*s/min; p < 0.001) and ΔEAdi (10 [7–13] vs. 14 [9–16] µV; p = 0.022). …”
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“…RESULTS: In the CCC group and the 30:2 group, peak inspiratory pressure (PIP) was 58.6 and 35.1 cmH(2)O (p < 0.001), minute volume (MV) 2189.6 and 1267.1 ml (p < 0.001), peak expired carbon dioxide (PECO(2)) 28.6 and 39.4 mmHg (p = 0.020), partial pressure of carbon dioxide (PaCO(2)) 50.2 and 61.1 mmHg (p = 0.013) and pH 7.3 and 7.2 (p = 0.029), respectively. …”
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“…RESULTS: Female patients were more represented in 2020-2021 than in 2013-2016 (48% compared to 66.1%, p<0.001), and the median age increased from 12 to 14 y.o. (p<0.05). Compared to a few years before, we registered a 280.79% increase in the admissions to the CAP ED, resulting in 252 admissions in 38 months (2013-2016) compared to 303 in 12 months (2020-2021) (p<0.001). …”
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“…RESULTS: In univariate analysis, older mean age (58.1 y.o. vs 49.3 y.o, p< 0.001), higher mean American Society of Anesthesia score (2.1 vs 1.9, p< 0.001), and longer hospital stay relating to the ankle fracture (6.3 days vs 4.1 days, p< 0.001) were correlated with SSI risk when compared to non-infected patients. …”
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“…RESULTS: The cuff pressure was significantly lower in piglets with the pneumatic device than in piglets without the pneumatic device (median (interquartile range), 18.6 (11–19.4) cmH(2)O versus 26 (20–56) cmH(2)O, P = 0.009). No significant difference was found in the percentage of time spent with a cuff pressure <15 cmH(2)O and that with a cuff pressure between 30 and 50 cmH(2)O. …”
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“…PaO(2)/F(I)O(2 )(204 ± 9 versus 165 ± 9 mmHg, P = 0.005) and static lung compliance (49.1 ± 2.9 versus 33.7 ± 2.7 mls/cm H(2)O, P < 0.001) were higher in the treatment group than the control group over seven days. …”
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“…Their usefulness stems from the ability to act on a diverse range of phenolic compounds such as o-/p-quinols, aminophenols, polyphenols, polyamines, aryl diamines, and aromatic thiols. …”
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“…After 24 h in prone position, PaO(2)/FiO(2) ratio significantly increased from 111 (84–128) to 173 (120–203) mmHg (p < 0.0001) while respiratory system compliance increased from 18 (12–36) to 32 (15–36) ml/cmH(2)O (p < 0.0001). Twenty-four hours after the return to supine position, tidal volume was increased from 3.0 (2.2–4.0) to 3.7 (2.8–5.0) ml/kg (p < 0.005). …”
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“…In the univariate analysis, ΔPrs averaged 13.7 ± 3.7 and 12.8 ± 3.7 cmH(2)O (P = 0.002) in nonsurvivors and survivors, respectively. …”
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“…We found that in term of average highest renal pelvic pressure (26.37±13.2 vs. 19.30±10.4 cmH(2)O, P<0.05), average operating time (68.4±9.5 vs. 46.7±8.3 minutes, P<0.05), average stone-free time (49.2±10.4 vs. 35.9±6.6 minutes, P<0.05), which was significantly different. …”
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“…RESULTS: Exercising with slow speed of movement was associated to larger muscle deoxygenation than normal speed of movement, as revealed by significant interaction (set × condition) for ΔHb (p = 0.01), and by significant main effects of condition for ΔHbO (p = 0.007) and ΔStO(2) (p = 0.016). With regards to the prefrontal cortex, contralateral lobe showed larger oxygenation increase than the ipsilateral one for ΔHb, ΔHbO, ΔHbT, ΔStO(2) in each set (main effect of lobe: p < 0.05). …”
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“…Within 3 min of birth [median (IQR)], mean airway pressures [12 (6–15) vs. 19 (16–23) cmH(2)O, p < 0.001] and FiO(2) [0.30 (0.28–0.31) vs. 0.22 (0.21–0.30), p < 0.001] were different in low- vs. high-pressure groups, respectively. …”
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“…CONCLUSIONS: In the hypermineralized dentine, high MgO + CaO + P(2)O(5) suggests that almost pure Mg containing tricalciumphosphate (MgTCP: (ß-Ca(3)(PO(4))(2)) (whitlockite) is present, with little or no hydroxyapatite. …”
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“…The intrinsic PEEP significantly decreased with higher PEEP (1.1 [1.0–2.3] vs 0.6 [0.0–1.0] cmH(2)O; p < 0.001). The applied tidal volume was significantly lower (480 [430–540] vs 520 [445–600] mL at 5 cmH(2)O of PEEP; 480 [430–540] vs 510 [430–590] mL at 15 cmH(2)O) in patients with intrinsic PEEP, while the respiratory rate was significantly higher (18 [15–20] vs 15 [13–19] bpm at 5 cmH(2)O of PEEP; 18 [15–20] vs 15 [13–19] bpm at 15 cmH(2)O). …”
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“…Furthermore, four of the nine flavonoid compounds [Hyperin/Hyperoside, HK-2; Cannabiscitrin, HK-3; 3-O-kaempferol-3-O-acetyl-6-O-(p-coumaroyl)-β-D-glucopyranoside, HK-11; 8-(2’’-pyrrolidione-5’’-yl)-quercetin, HK-B10] induced the differentiation of murine pre-osteoblast MC3T3-E1 cells. …”
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“…A diaphragm thinning of more than 10% was associated with longer duration of controlled ventilation (10 [5, 15] versus 5 [4, 8.5] days, p = 0.004) and higher PEEP levels (12.6 ± 4 versus 10.4 ± 4 cmH(2)O, p = 0.034). An increase in diaphragm thickness of more than 10% during assisted ventilation was not associated with any clinical outcome but with lower respiratory rate (16.7 ± 3.2 versus 19.2 ± 4 bpm, p = 0.019) and Rapid Shallow Breathing Index (37 ± 11 versus 44 ± 13, p = 0.029) and with higher Pressure Muscle Index (2 [0.5, 3] versus 0.4 [0, 1.9], p = 0.024). …”
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“…On admission, those who deteriorated were significantly older (73 [60–82] vs 63 [45–78] y-o, p < 0.001) and presented significantly higher SOFA scores (2.15 ± 1.61 vs 1.56 ± 1.40, p = 0.003). …”
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