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  1. 2181
    “…The resulting debriefing approach was based on the “S.T.O.P.” structure (Summarise the case; Things that went well; Opportunities for improvement; Points of action). …”
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    Interdisciplinary clinical debriefing in the emergency department: an observational study of learning topics and outcomes
  2. 2182
    “…The median EPAP did not differ between the EFL(T)-abolishing-EPAP and the fixed-EPAP night (median (IQR) = 7.0 (6.0, 8.8) cmH(2)O during night vs 7.5 (6.5, 10.5) cmH(2)O, p = 0.365). We found no differences in mean PtcCO(2) (44.9 (41.6, 57.2) mmHg vs 54.5 (51.1, 59.0), p = 0.365), the percentage of night time with PtcCO(2) > 45 mm Hg was lower (62(8,100)% vs 98(94,100)%, p = 0.031) and ineffective efforts were fewer (126(93,205) vs 261(205,351) events/hour, p = 0.003) during the EFL(T)-abolishing-EPAP than during the fixed-EPAP night. …”
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    Effect of nocturnal EPAP titration to abolish tidal expiratory flow limitation in COPD patients with chronic hypercapnia: a randomized, cross-over pilot study
  3. 2183
    “…In a subset of 108 patients, day-14 Crs decreased compared to day-1 Crs (31.2 ± 14.4 mL/cmH(2)O vs 37.8 ± 11.4 mL/cmH(2)O, p < 0.001). The decrease in Crs was not associated with day-28 outcome. …”
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    Static compliance of the respiratory system in COVID-19 related ARDS: an international multicenter study
  4. 2184
    “…The analgesic satisfaction of patients in Group QO was higher than the Group S (p = 0.001) and Group O (p = 0.012). CONCLUSIONS: TQLB combined with oxycodone-based PCIA provided satisfactory postoperative analgesia and reduced oxycodone consumption in patients following laparoscopic hepatectomy. …”
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    Ultrasound-guided transmuscular quadratus lumborum block reduced postoperative opioids consumptions in patients after laparoscopic hepatectomy: a three-arm randomized controlled trial
  5. 2185
    “…RESULTS: Transpulmonary peak pressure and histological damage score were higher in BIVENT(High-Effort) compared to BIVENT(Low-Effort) and PSV [16.1 ± 1.9cmH(2)O vs 12.8 ± 1.5cmH(2)O and 12.5 ± 1.6cmH(2)O, p = 0.015, and p = 0.010; median (interquartile range) 11 (9–13) vs 7 (6–9) and 7 (6–9), p = 0.021, and p = 0.029, respectively]. …”
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    Impact of positive biphasic pressure during low and high inspiratory efforts in Pseudomonas aeruginosa-induced pneumonia
  6. 2186
    “…Median PEEP was similar in patients with LIPS < 4 and LIPS ≥ 4, but higher in patients with ARDS (five [5–7], five [5–8], and 10 [5–12] cmH(2)O; P < 0.0001). The proportions of patients with LIPS ≥ 4 or with ARDS were 68% (95% CI: 66–71) and 7% (95% CI: 6–8), respectively. …”
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    Epidemiological Characteristics, Ventilator Management, and Clinical Outcome in Patients Receiving Invasive Ventilation in Intensive Care Units from 10 Asian Middle-Income Countries (PRoVENT-iMiC): An International, Multicenter, Prospective Study
  7. 2187
    “…METHODS: Pregnant C57BL/6 J mice were administered environmentally relevant concentrations of DDTs (p,p’-DDT and o,p’-DDT) or DDE (p,p’-DDE), 1.7 mg/kg and 1.31 mg/kg, respectively, from gestational day 11.5 to postnatal day 5 by oral gavage, and longitudinal body temperature was recorded in male and female offspring. …”
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    Developmental exposure to DDT or DDE alters sympathetic innervation of brown adipose in adult female mice
  8. 2188
    “…In addition to the tissue-specific accumulation of metabolites, we noticed a cooperative relationship between leaves, fresh carpels, and developing seeds in terms of metabolites transfer. Delphinidin-3-O-(6ʺ-O-p-coumaroyl)glucoside and most of the flavonols were up-regulated in the purple flowers indicating they might be responsible for the purple coloration. …”
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    Comparative metabolomics analysis of different sesame (Sesamum indicum L.) tissues reveals a tissue-specific accumulation of metabolites
  9. 2189
    “…The results indicated that, from the eight organochlorine pesticides analyzed in 447 breast milk samples at three sampling times, DDT and its metabolites were detected. p,p′-DDE and p,p′-DDT were detected in all (100%) of the breast milk samples while, p,p-DDD, and o,p-DDT were detected in 53.9%, and 42.7%, respectively. …”
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    Exposure of infants to organochlorine pesticides from breast milk consumption in southwestern Ethiopia
  10. 2190
    “…The primary outcome occurred in 54 (16.8%) patients under 45 y/o vs. 783 (30.7%) in patients aged > 45 y/o (P < 0.001), with a strong impact on the death rate (3 (0.9%) vs. 358 (14.0%), P < 0.001). …”
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    COVID-19 in young patients: Less cardiovascular risk factors but more specific cardiovascular complications
  11. 2191
    “…The median applied positive end expiratory pressure was lower in MICs than in HICs (5 [IQR 5–8] vs 6 [5–8] cm H(2)O; p=0·0011). ICU mortality was higher in MICs than in HICs (30·5% vs 19·9%; p=0·0004; adjusted effect 16·41% [95% CI 9·52–23·52]; p<0·0001) and was inversely associated with gross domestic product (adjusted odds ratio for a US$10 000 increase per capita 0·80 [95% CI 0·75–0·86]; p<0·0001). …”
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    Geoeconomic variations in epidemiology, ventilation management, and outcomes in invasively ventilated intensive care unit patients without acute respiratory distress syndrome: a pooled analysis of four observational studies
  12. 2192
    “…OS municípios AC e as CR apresentaram risco relativo de 1,05 (1,03-1,06) e 1,17 (1,16-1,19) respectivamente. Em todas as análises o p < 0,001, exceto pela mortalidade nos municípios BC cujo p = 0,003. …”
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    INCIDÊNCIA E MORTALIDADE POR COVID-19 NO ESTADO DE SÃO PAULO: ONDE ESTÃO OS MUNICÍPIOS MAIS ATINGIDOS PELA PANDEMIA?
  13. 2193
    “…Univariable analysis showed that patients with acute kidney injury were older (difference 8 years, P < 0.001); had higher body mass index (difference 1.68 kg·m(−2), P = 0.002); rates of smoking (OR = 2, P = 0.020), hypertension (OR = 2.83, P = 0.004), and renal dysfunction (OR = 3.58, P = 0.002); higher central venous pressure (difference 3 cm H(2)O, P < 0.001); and lower cardiac index (difference −0.23 L·min(−1)·m(−2), P < 0.001) than patients without acute kidney injury. …”
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    A Prediction Model for Acute Kidney Injury After Pericardiectomy: An Observational Study
  14. 2194
    “…PURPOSE: 4-Borono-2-[(18)F]fluoro-l-phenylalanine ([(18)F]FBPA) synthesized with [(18)F]F(2), produced using the (18)O(p, n)(18)F reaction, has been reported for increasing radioactivity. …”
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    Improved Stability and Practicality for Synthesis of 4-Borono-2-[(18)F]fluoro-l-phenylalanine by Combination of [(18)O]O(2) Single-Use and [(18)F]CH(3)COOF Labeling Agents
  15. 2195
    “…A progressive decrease was observed in arterial carbon dioxide partial pressure (PaCO(2)) and end-tidal carbon dioxide (ETCO(2)) when the airway pressures were increased above 9 cmH(2)O (p < 0.001). The increase in airway pressure promoted an elevation in pH (p < 0.001). …”
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    Computed Tomography Assessment of Tidal Lung Overinflation in Domestic Cats Undergoing Pressure-Controlled Mechanical Ventilation During General Anesthesia
  16. 2196
    “…PGF consists mainly of gypsum (CaSO(4)·2H(2)O), P(2)O(5), SiO(2,) and other impurities, including a minor amount of rare earth elements, REEs. …”
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    Alkali treatment–acid leaching of rare earth elements from phosphogypsum fertilizer: insight for additional resource of valuable components
  17. 2197
    “…Further transcriptional analyses suggested that TnmR7 could promote the expressions of core enzymes TnmD/G and TnmN/O/P, while TnmR3 may act as a sensor kinase to work with TnmR1 and form a higher class unconventional orphan two-component regulatory system, which dynamically represses the expressions of TnmR7, core enzymes TnmD/G/J/K1/K2 and auxiliary proteins TnmT2/S2/T1/S1. …”
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    Deciphering the pathway-specific regulatory network for production of ten-membered enediyne Tiancimycins in Streptomyces sp. CB03234-S
  18. 2198
    “…RESULTS: Global driving pressure was different between the groups (14 vs 11 cm H2O, p = 0.03). The individualized mechanical ventilation group had lower concentrations in bronchoalveolar lavage of IL-6 (270 pg/mL vs 155 pg/mL, p = 0.02), TNF-α (292 pg/mL vs 139 pg/mL, p < 0.01) and IL-1ß (563 pg/mL vs 131 pg/mL, p = 0.05). …”
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    Individualizing mechanical ventilation: titration of driving pressure to pulmonary elastance through Young’s modulus in an acute respiratory distress syndrome animal model
  19. 2199
    “…INTRODUCTION: Mitotane (o,p'–DDD) is the drug of choice for adrenocortical carcinomas (ACC) and its measurement in plasma is essential to control drug administration. …”
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    PSAT096 Development and Validation of Mitotane Determination in Plasma Samples by LC-DAD
  20. 2200
    por Beltsevich, Dmitry, Roslyakova, Anna
    Publicado 2022
    “…BACKGROUND: Mitotane/o,p'DDD is adrenolytic and antitumor therapeutic agent used in the first line drug therapy of advanced adrenocortical carcinoma (ACC) as well as an adjuvant therapy after surgical resection of the primary tumor at moderate/high risk of recurrence. …”
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    ODP597 Clinical case of uncomplicated pregnancy in a patient with adrenocortical carcinoma during treatment with mitotane
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