“…Patients with positive end-expiratory pressure (PEEP) ≥ 10 cm H(2)O had a lower V(MIN) and V(BEST) than patients with PEEP < 10 cm H(2)O, P > 0.05. Patients in the supine position had a higher esophageal pressure than those in the prone position with the same balloon filling volume. …”
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“…There are numerous ways of treating T2DM with empagliflozin, including by regulating apoptosis, cell aging, as well as the NF-κB, HIF-1HIF-1, Ras, MAPK, FoxO, P13K-Akt, and p53 pathways.…”
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“…[Zn{O(2)P(OPh)(2)}(2)](∞) (1), formed from the reaction of Zn[N(SiMe(3))(2)](2) with HO(O)P(OPh)(2) coordinates to donor-base ligands, i.e., pyridine (Py), 4-methylpyridine (4-MePy), 2,2-bipyridine (bipy), tetramethylethylenediamine (TMEDA), pentamethyldiethylenetriamine (PMDETA), and 1,3,5-trimethyl-1,3,5-triazacyclohexane (Me(3)-TAC), to produce polymeric 1D structures, [(Py)(2)Zn{O(2)P(OPh)(2)}(2)](∞) (2) and [(4-MePy)(2)Zn{O(2)P(OPh)(2)}(2)](∞) (3), the bimetalic systems, [(Bipy)Zn{O(2)P(OPh)(2)}(2)](2) (4), [(TMEDA)Zn{O(2)P(OPh)(2)}(2)](2) (5), and [(Me(3)-TAC)Zn{O(2)P(OPh)(2)}(2)](2) (7), as well as a mono-nuclear zinc bis-diphenylphosphate complex, [(PMDETA)Zn{O(2)P(OPh)(2)}(2)] (6). (1)H NMR DOSY has been used to calculate averaged molecular weights of the species. …”
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“…Tunk inclination from a semirecumbent (45°) to a supine-flat (10°) position resulted in a higher tidal volume [371 (± 76) vs. 433 (± 84) mL (P < 0.001)] and respiratory system compliance [34 (± 10) to 41 (± 12) mL/cmH(2)O (P < 0.001)]. The CO(2) exhaled per minute improved from 191 mL/min (± 34) to 227 mL/min (± 38) (P < 0.001). …”
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“…Overall, the median PEEP increased form 6 (IQR 5–8) to 10 (IQR 8–12) cmH(2)O (p = 0.001), the median PbtO(2) increased from 21 (IQR 16–29) mmHg to 23 (IQR 18–30) mmHg (p = 0.001), while ICP remained unchanged [from 12 (7–18) mmHg to 12 (7–17) mmHg; p = 0.42]. …”
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“…J. Cordoba-Chacon: None. O.P. McGuinness: None. R.D. Kineman: None. It is commonly accepted that GH reduces the actions of insulin. …”
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“…During stage 2, there were significant reductions in weight (mean 15.7 (SD 8.0) kg, P<0.001), intracranial pressure (mean 8.0 (SD 4.2) cm H(2)O, P<0.001), score on headache impact test (7.6 (SD 10.1), P=0.004), and papilloedema (optic disc elevation (mean 0.15 (SD 0.23) mm, P=0.002), diameter of the nerve sheath (mean 0.7 (SD 0.8) mm, P=0.004), and thickness of the peripapillary retina (mean 25.7 (SD 36.1) µ, P=0.001)). …”
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“…For each condition, the mean expiratory Pvent was always higher (for all conditions 4.0 ± 1.1 vs. 1.1 ± 0.5 cmH(2)O, P < 0.01) in cNAVA than in tNAVA. Relative to tNAVA, mean inspiratory EAdi was reduced on average (for all conditions) by 19 % (range 14 %–25 %), p < 0.05. …”
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“…Driving pressure was significantly reduced during the first two days compared to baseline (from 13.9 to 11.6 cmH(2)O; p < 0.05) and there were no significant differences in the values of respiratory system compliance. …”
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“…An Agilent SureSelect 2Mb capture array captured genic sequence for 342 genes nominally associated with complicated SAB in discovery (SKAT-O P < 0.035). Sequencing and data analysis proceeded as for WES. …”
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“…In particular, driving pressure was significantly decreased after ECMO support (29.5 vs. 16.8 cmH(2)O, p < 0.001). The weaning success rate was 86.7%, and the rate of survival to hospital discharge was 83.5%. …”
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“…Compared with successfully weaned patients (n = 14), the 21 unsuccessfully weaned patients had a longer duration of IPPV pre-ECMO (6 ± 4 d vs. 2 ± 1 d, P < 0.01) as well as a higher P(plat) (25 ± 5 cmH(2)O vs. 21 ± 3 cmH(2)O, P < 0.05) and VT (343 ± 96 ml vs. 246 ± 93 ml, P < 0.05) after 48 h on ECMO support. …”
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“…Risks factors for no vaccination despite indication were: younger age (67 vs. 75y-o, P < 0.05) and less comorbidity (Charlson index 4 vs. 5, P < 0.01). …”
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“…Paw was greater in NAVA (21 ± 3 cmH(2)O) than in PSV (19 ± 3 cmH(2)O, p = 0.001). Most patients were under continuous sedation during the study. …”
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“…Inspiratory plateau pressure was comparable in both groups (31 ± 2 vs 34 ± 2 cm H(2)O; p = 0.16). Flow-controlled ventilation increased normally aerated (24% ± 4% vs 10% ± 2%; p = 0.004) and decreased nonaerated lung volume (23% ± 6% vs 38% ± 5%; p = 0.033) in the dependent lung region. …”
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“…In a subgroup of 20 patients with available gas exchange data, increasing PEEP decreased respiratory system compliance (median difference, MD − 9 ml/cmH(2)O, 95% CI from − 12 to − 6 ml/cmH(2)O, p < 0.001) and the ventilatory ratio (MD − 0.1, 95% CI from − 0.3 to − 0.1, p = 0.003), increased PaO(2) with FiO(2) = 0.5 (MD 24 mmHg, 95% CI from 12 to 51 mmHg, p < 0.001), but did not change PaO(2) with FiO(2) = 1.0 (MD 7 mmHg, 95% CI from − 12 to 49 mmHg, p = 0.313). …”
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“…Moreover, cerebrospinal fluid examinations revealed that cryptococcal meningitis patients with type II diabetes mellitus had higher opening pressure (271.54 vs. 234.23 mmH(2)O; P = 0.125).The results of multivariate regression analysis revealed that cryptococcal meningitis patients with type II diabetes were more often presented with visual disorders (28.54% vs. 11.54%; [95% CI 0.056–0.705]; p = 0.012), and had higher cerebrospinal fluid protein levels (1027.62 ± 594.16 vs. 705.72 ± 373.88 mg/l; [95% CI 1.000–1.002]; p = 0.016). …”
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“…PAWP at pneumoperitoneum pressure and in the Trendelenburg position was significantly lower in the AutoFlow group than in the VCV group [median (interquartile range), 16 (15–18) cmH(2)O vs. 18 (17–19) cmH(2)O; P < 0.001]. Similarly, patients in the AutoFlow group showed lower PAWP at the other three timepoints measured. …”
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“…Ptr,stim within 24 h after intubation was lower in septic patients as compared to non-septic patients: 6.3 (4.9–8.7) cmH(2)O vs. 9.8 (7.0–14.2) cmH(2)O (p = 0.004), respectively. The median (interquartile) duration of mechanical ventilation between first and second diaphragm evaluation was 4 (2–6) days in septic patients and 3 (2–4) days in non-septic patients (p = 0.073). …”
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“…RESULTS: The median CSA was 35.5º with no differences between those with failure (median 35.5º, range 29º to 48.2º) and success of conservative treatment (median 35.45º, range 30.2º to 40.3º), p = 0.978. The multivariate analysis showed a younger age in patients with failure of conservative treatment (56.14 ± 9.2 vs 67.8 ± 8.4, p < 0.001) and that male gender was also associated with failure of conservative treatment (57% of men required surgery vs 28% of women, p = 0.035). …”
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