“…Results: In lungs, the liberal group showed increased transpulmonary plateau pressure compared with the restrictive group (liberal, 23.5 ± 2.9 cmH(2)O; restrictive, 18.8 ± 2.3 cmH(2)O, p = 0.046) under PEEP = 9 cmH(2)O. Gene expression associated with inflammation (interleukin [IL]-6) was higher in the liberal-PEEP9 group than the liberal-PEEP3 group (p = 0.006) and restrictive-PEEP9 (p = 0.012), Regardless of the fluid strategy, lung mechanical power and the heterogeneity index were higher, whereas birefringence for claudin-4 and zonula-ocludens-1 gene expression were lower in the PEEP9 groups. …”
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“…Further, in this subgroup, P/F ratio (148 (81.3-219.3) mmHg to 317 (153.9-403.3) mmHg; p= 0.0002) and C(dyn) (16.6 (12.2-26.4) ml/cmH(2)O to 21.8 (14.6-29.8) ml/cmH(2)O; p=0.05) improved significantly by proning. Nevertheless, length of mechanical ventilation, length of intensive care unit (ICU) and hospital stay were significantly longer with a median of 2 (1.8-9.3), 12 (7-29) and 35 (21-53) days in the proning group compared to 1.4 (0.9-2.8), 7 (4-13) and 25 (18-37) days in the non-proning group (all p<0001). …”
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“…The radiochemical purity analysis of LyeTx I-K-HYNIC-(99m)Tc showed that the optimal radiolabeling conditions (10 μg of LyeTx I-K-HYNIC; 250 μg of SnCl(2)(.)2H(2)O; pH = 7; heating for 15 min) yielded a radiochemical purity of 87 ± 1 % (n = 3). …”
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“…The maxillary first premolars showed progressive and significantly smaller mesial angulation in JJG, FCG and DJG, respectively (14.65±6.31º, 8.43±3.99º, 0.97±3.16º; p<0.001). They also showed greater mesialization in JJG than FCG (3.76±1.46 mm vs. 2.27±1.47 mm, p=0.010), and greater extrusion in DJG compared to JJG (0.90±0.77 mm vs 0.11±0.60 mm, p=0.004). …”
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“…In the corresponding glandular cells, NO had higher mRNA levels for IL-6, IL-8, ER-α, and ER-β than O (P<0.05). Immunostaining with anti-Ki67 antibodies indicated that O glandular cells were 3-fold less proliferative than those for NO, consistent with their lower Cyclin D1 mRNA levels (P<0.05). …”
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“…The PaO(2)/FiO(2)-matched-ARDS and COVID-19-ARDS populations (both with PaO(2)/FiO(2) 106 ± 59 mmHg) had different respiratory system compliances (Crs) (39 ± 11 vs 49.9 ± 15.4 ml/cmH(2)O, p = 0.03). The Compliance-matched-ARDS and COVID-19-ARDS had similar Crs (50.1 ± 15.7 and 49.9 ± 15.4 ml/cmH(2)O, respectively) but significantly lower PaO(2)/FiO(2) for the same Crs (160 ± 62 vs 106.5 ± 59.6 mmHg, p < 0.001). …”
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“…PaO(2) increased in lavage injured lungs in response to incremental PEEP (5–20 cm H(2)O) (p < 0.01). At fixed low oxygen flow rates (5 L/min), delivered FiO(2) decreased with increased V(E). …”
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“…RESULTS: Inspiratory positive airway pressure 24 h after randomisation was significantly higher (28.0 [26.0–28.0] vs. 15.5 [15.0–17.5] cmH(2)O; p = 0.000) and NPPV duration within the first 24 h was significantly longer (21.8 ± 2.1 vs. 15.3 ± 4.7 h; p = 0.001) in the high-intensity NPPV group. …”
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“…For AD, ACLR + LMORT3 tear and PM resulted in significantly greater anterior translation (0.8-2.1 mm differences) compared to ACL-intact at all angles (P < 0.05) and compared to ACLR at 60(o) and 90(o) (P < 0.014). For PS, ACLR + LMORT3 tear had significantly more anterior translation (1-1.4 mm differences) at 15(o) than intact knees (P=0.041), and at 0(o) and 15(o) for PM (P < 0.03). …”
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“…At admission mean PaO(2)/FiO(2)-ratio was 184.3 (SD 61.4) vs. 151.3 (SD 54.4) mmHg, (p = 0.017) and PEEP was 11.8 (SD 2.8) cmH(2)O vs. 11.3 (SD 3.4) cmH(2)O, (p = 0.475), for ICU survivors and non-survivors. …”
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“…The area under the receiver operating characteristic curve for FTc in predicting volume responsiveness was 0.921, 0.805, and 0.719 when PEEP was 0, 5, and 10 cmH(2)O (P < 0.05), respectively, and the cutoff value of FTc for diagnosing volume responsiveness was 323.42 milliseconds, 326.69 milliseconds, and 312.03 milliseconds, respectively. …”
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“…No significant difference between the two groups was observed on PaO(2)/FiO(2) ratio (end of surgery: 339 ± 149 vs. 304 ± 131, p = 0.8; one hour after ICU: 324 ± 115 vs. 329 ± 124, p = 1), driving pressure (end of surgery: 7 ± 1 vs. 8 ± 1 cmH(2)O, p = 0.3; one hour after ICU: 9 ± 3 vs. 9 ± 3 cmH(2)O), duration of mechanical ventilation (5.5 ± 4.8 vs 8.2 ± 10.0 h, p = 0.5), need postoperative respiratory support (2 vs. 1, p = 1), occurrence of pneumopathy (2 vs. 0, p = 0.5) and radiographic atelectasis (7 vs. 8, p = 1). …”
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“…Device switch was associated with significant reductions from baseline in expiratory PAP {from 12 [11–13] to 8 [7–9] cmH(2)O at 3 months (P<0.001) and 9 [8–12] cmH(2)O at 1 year (P=0.005)}, 95(th) percentile pressure {from 14 [12–14] to 10 [9–11] and 10 [8–11] cmH2O; P<0.001 and P=0.001, respectively} and leak {from 1 [0–6] to 0 [0–1] and 0 [0–2] L/min; P=0.049 and P=0.033, respectively}. …”
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“…No differences were found in mean age and gender (67.0±9.1 vs 67.0±10.02 y.o, p=0.96 and 26.6% vs 24.4% of women, p=0.8). No differences were found with regard to previous cardiopathy or other comorbidities. …”
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“…The mean pre op posterior tibial slope was 19.2o ±4.1o and 7.7o ±2.3o following HTO (mean diff: -11.5o, P <.001). Mean time to follow-up was 1.82 ±0.3 years. …”
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“…The mean pre operative posterior tibial slope was 19.2(o) ±4.1(o) and 7.7(o) ±2.3(o) following HTO (mean diff: -11.5(o), P <.001). Mean time to follow-up was 1.82 ±0.3 years. …”
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“…Results Participants in the LI arm were significantly older (71.3±4 vs 48.2±10 y.o., p < 0.001) and lighter (93.4 ± 8 vs. 118.5±18 kg, P=0.001) compared to the BS arm. …”
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“…Ces miARN ciblaient 1195 gènes, impliqués dans la signalisation MAPK, FoxO, p53, l’apoptose, la signalisation interleukin-4 et interleukin-13, la réponse cellulaire au dommage de l’ADN, la régulation négative de l’expression génique et la traduction, le processus viral et phosphorylation. …”
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“…. − 1.0 (IQR − 3.7–3.0) mL/cmH(2)O, P = 0.006] after prone positioning compared with patients who did not. …”
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“…A correlação de 0,494 não foi considerada estatisticamente significante, mas o p-valor ficou próximo do limite de aceitação com 0,052. …”
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