“…BACKGROUND: Around 25 to 30% of patients with obsessive-compulsive disorder (OCD) do not respond to treatment. These patients have the longest duration of disease and the worst prognosis. …”
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“…Obsessive compulsive disorder (OCD) can manifest as a debilitating disease with high degrees of co-morbidity as well as clinical and etiological heterogenity. …”
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“…Obsessive-compulsive disorder (OCD) is a psychiatric condition with an estimated lifetime prevalence of between 1 and 2%. …”
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“…Obsessive-compulsive disorder (OCD) and eating disorders (ED) share common causal factors and often represent similar entities. …”
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“…The number of patients receiving both psychological and pharmacological therapy for OCD increased. There were low numbers of patients completing questionnaires for OCD, which would be a useful way to identify changes in symptoms across patients. …”
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“…Some evidence supported a possible role of infections also in the pathophysiology of OCD. Infections from Herpes simplex virus 1, Borna disease virus, Group A-Beta Hemolytic Streptococcus, Borrelia spp., and Toxoplasma gondii were actually found in patients with OCD. …”
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“…The control group showed a higher drifting rate than the OCD group, indicating that the OCD group was less sensitive to evidence. …”
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“…INTRODUCTION: Background: Obsessive-compulsive disorder (OCD) is a condition that includes distressing obsessions and repetitive compulsions. …”
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“…OCD is characterized by obsessions and compulsions that cause distress, are time-consuming, and interfere with a patient's social, occupational, or other areas of functioning. …”
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“…The neurobiological understanding of obsessive–compulsive disorder (OCD) includes dysregulated frontostriatal circuitry and altered monoamine transmission. …”
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“…Thus, the aim of the current functional magnetic resonance imaging (fMRI) study was to test the direct association between polygenic risk for OCD and neural activity during the performance of a numeric n-back task with four working memory load conditions in 128 participants, including patients with OCD, unaffected first-degree relatives of OCD patients, and healthy controls. …”
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“…BACKGROUND: This study assesses the psychometric properties of the German version of the Padua Inventory-Washington State University Revision for measuring pediatric OCD. METHODS: The parent-rating and self-rating inventory is assessed in a clinical sample (CLIN: n = 342, age range = 6–18 years) comprising an OCD subsample (OCDS: n = 181) and a non-OCD clinical subsample (non-OCD: n = 161), and in a community sample (COS: n = 367, age range = 11–18 years). …”
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“…A pandemic outbreak can lead to excessive, maladaptive levels of anxiety, particularly among individuals who already suffer from obsessive-compulsive disorder (OCD). The Coronavirus Disease 2019 (COVID-19) provided a novel opportunity to examine the possibility that individuals with OCD, compared to those without OCD, might experience greater distress from this common stressor. …”
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“…A third proposition is that depression is an essential part of OCD but that OCD is a separate disorder from depression. …”
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“…This case report highlights the need of investigating a new onset childhood OCD. • AIM: To report the Paediatric OCD associated with streptococcal infection. • METHODS: We evaluated a 7-year-old child in OPD who presented with obsessions and compulsions for 3 months with no previous psychiatric history. • RESULTS: Patient detailed history was taken. …”
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“…This review discusses the rationale for and theory behind neuromodulation in the treatment of OCD.…”
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“…The rationale for its administration in psychiatric conditions is based on its ability reducing synaptic glutamate release, which was found to be increased in the cerebrospinal fluid of OCD patients. OBJECTIVES: Evaluating N-acetylcysteine efficacy in OCD symptoms. …”
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