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1001por Shaw, Philip, Sharp, Wendy, Sudre, Gustavo, Wharton, Amy, Greenstein, Deanna, Chakravarty, M. Mallar, Lerch, Jason P., Rapoport, Judith“…Endophentoypes, quantifiable traits lying on the causal chain between a clinical phenotype and etiology, can be used to accelerate genomic discovery in Obsessive-Compulsive Disorder (OCD). Here we identify the neuroanatomic changes that are shared by 22 OCD adult and adolescent patients and 25 of their unaffected siblings who are at genetic risk for the disorder. …”
Publicado 2014
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1002por Yazdi-Ravandi, Saeid, Akhavanpour, Hassan, Shamsaei, Farshid, Matinnia, Nasrin, Ahmadpanah, Mohammad, Ghaleiha, Ali, Khosrowabadi, Reza“…In this study, resting state EEG data of 39 outpatients with OCD and 19 healthy controls (HC) were recorded. …”
Publicado 2018
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1003“…CONCLUSION: Our findings implicate areas previously reported to be involved in OCD, as well as areas not typically implicated in OCD, suggesting that the neurobiological profile of TS+OCD is intermediate to pure TS and pure OCD.…”
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1004por Li, Hailong, Hu, Xinyu, Gao, Yingxue, Cao, Lingxiao, Zhang, Lianqing, Bu, Xuan, Lu, Lu, Wang, Yanlin, Tang, Shi, Li, Bin, Yang, Yanchun, Biswal, Bharat B., Gong, Qiyong, Huang, Xiaoqi“…Furthermore, activity in the cerebellum had an excitatory influence on the right DLPFC in OCD patients. These findings may help to elucidate the psychopathology of OCD by detailing the directional connectivity between the DLPFC and the rest of the brain, ultimately helping to identify regions that could serve as treatment targets in OCD.…”
Publicado 2020
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1005por Martínez-Esparza, Inmaculada Concepción, Olivares-Olivares, Pablo J., Rosa-Alcázar, Ángel, Rosa-Alcázar, Ana I., Storch, Eric A.“…OCD severity, comorbidity patterns, anxiety, and obsessive beliefs may influence performance.…”
Publicado 2021
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1006“…Anorexia nervosa (AN) and obsessive–compulsive disorder (OCD) exhibit a high co-morbidity rate, similar symptoms, and a shared genetic basis. …”
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1007por de Oliveira, Marcos Vinícius Sousa, de Barros, Pedro Macul Ferreira, de Mathis, Maria Alice, Boavista, Rodrigo, Chacon, Priscila, Echevarria, Marco Antonio Nocito, Ferrão, Ygor Arzeno, Vattimo, Edoardo Felippo de Queiroz, Lopes, Antônio Carlos, Torres, Albina Rodrigues, Diniz, Juliana Belo, Fontenelle, Leonardo F., do Rosário, Maria Conceição, Shavitt, Roseli Gedanke, Miguel, Eurípedes Constantino, da Silva, Renata de Melo Felipe, Costa, Daniel Lucas da Conceição“…OBJECTIVES: To summarize evidence-based pharmacological treatments and provide guidance on clinical interventions for adult patients with obsessive-compulsive disorder (OCD). METHODS: The American Psychiatric Association (APA) guidelines for the treatment of OCD (2013) were updated with a systematic review assessing the efficacy of pharmacological treatments for adult OCD, comprising monotherapy with selective serotonin reuptake inhibitors (SSRIs), clomipramine, serotonin and norepinephrine reuptake inhibitors (SNRIs), and augmentation strategies with clomipramine, antipsychotics, and glutamate-modulating agents. …”
Publicado 2023
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1008“…Epigenetic alterations in the oxytocin receptor gene (OXTR) may be a molecular mechanism in the pathogenesis of obsessive-compulsive disorder (OCD). This study investigated the association between OXTR DNA methylation and the OCD status of a Korean population. …”
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1009por Kasal, Meltem I., Besiroglu, Lutfullah, Zorlu, Nabi, Dikmeer, Nur, Bilge, Aslıhan, Durmaz, Ercan, Polat, Serap, Gelal, Fazil, Rapp, Michael, Heinz, Andreas, Sebold, Miriam“…We investigated 32 patients with OCD, 27 unaffected siblings (SIBs) and 31 healthy controls (HCs) using the two-step task. …”
Publicado 2021
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1010por Ravagnani Salto, Ana Beatriz, Santoro, Marcos L., Hoexter, Marcelo Q., Jackowski, Andrea Parolin, Pan, Pedro M., Rosário, Maria Conceição, Belangero, Sintia I., Alvarenga, Pedro Gomes, Doretto, Victoria Fogaça, Fumo, Afonso Mazine Tiago, Batistuzzo, Marcelo C., Macul Ferreira de Barros, Pedro, Timpano, Kiara R., Ota, Vanessa K., Rohde, Luis Augusto, Miguel, Euripedes Constantino, Leckman, James F., Zugman, André“…A secondary aim was to determine if there is a relationship between OCS and the individual's OCD polygenic risk score (OCD-PRS) and between the rate of thalamic volume change and the OCD-PRS. …”
Publicado 2021
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1011por Jia, Cuicui, Ou, Yangpan, Chen, Yunhui, Ma, Jidong, Zhan, Chuang, Lv, Dan, Yang, Ru, Shang, Tinghuizi, Sun, Lei, Wang, Yuhua, Zhang, Guangfeng, Sun, Zhenghai, Wang, Wei, Wang, Xiaoping, Guo, Wenbin, Li, Ping“…Disrupted functional asymmetry of cerebral hemispheres may be altered in patients with obsessive-compulsive disorder (OCD). However, little is known about whether anomalous brain asymmetries originate from inter- and/or intra-hemispheric functional connectivity (FC) at rest in OCD. …”
Publicado 2021
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1012por Akin-Sari, Burcin, Inozu, Mujgan, Haciomeroglu, A. Bikem, Cekci, Banu Cicek, Uzumcu, Elif, Doron, Guy“…Obsessive-compulsive disorder (OCD) is a persistent psychiatric disorder causing significant impairment in functioning. …”
Publicado 2022
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1013por Stern, Emily R., Eng, Goi Khia, De Nadai, Alessandro S., Iosifescu, Dan V., Tobe, Russell H., Collins, Katherine A.“…Obsessive-compulsive disorder (OCD) is highly heterogeneous. Although perseverative negative thinking (PT) is a feature of OCD, little is known about its neural mechanisms or relationship to clinical heterogeneity in the disorder. …”
Publicado 2022
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1014“…Attentional research in OCD has focused solely on threat stimuli, assumed to provoke related obsessions and ensuing compulsions. …”
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1015por Hearne, Luke J., Breakspear, Michael, Harrison, Ben J., Hall, Caitlin V., Savage, Hannah S., Robinson, Conor, Sonkusare, Saurabh, Savage, Emma, Nott, Zoie, Marcus, Leo, Naze, Sebastien, Burgher, Bjorn, Zalesky, Andrew, Cocchi, Luca“…Current behavioural treatment of obsessive‐compulsive disorder (OCD) is informed by fear conditioning and involves iteratively re‐evaluating previously threatening stimuli as safe. …”
Publicado 2023
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1016“…BACKGROUND: The recommended psychological treatment of choice for obsessive-compulsive disorder (OCD) is exposure with response prevention (ERP). …”
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1017por Benatti, Beatrice, Albert, Umberto, Maina, Giuseppe, Fiorillo, Andrea, Celebre, Laura, Girone, Nicolaja, Fineberg, Naomi, Bramante, Stefano, Rigardetto, Sylvia, Dell’Osso, Bernardo“…Sociodemographic and clinical variables of a sample of 123 OCD outpatients, currently attending three OCD tertiary clinics in Northern Italy, were assessed through telephone and in-person interviews. …”
Publicado 2020
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1018por Gillan, Claire M., Morein-Zamir, Sharon, Durieux, Alice M. S., Fineberg, Naomi A., Sahakian, Barbara J., Robbins, Trevor W.“…There is disagreement regarding the role of perceived control in obsessive–compulsive disorder (OCD). The present study used a traditional illusion of control paradigm (Alloy and Abramson, 1979) to empirically test control estimation in OCD. …”
Publicado 2014
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1019por Amiri Pichakolaei, Ahmad, Fahimi, Samad, Bakhshipour Roudsari, Abbas, Fakhari, Ali, Akbari, Ebrahim, Rahimkhanli, Masoumeh“…Objective: The present study aimed to investigate the metacognitive model of obsessive-compulsive disorder (OCD), through a comparative study of thought fusion beliefs and thought control strategies between patients with OCD, depression, and normal people. …”
Publicado 2014
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1020por Zhang, Sheng-Yang, Xu, Hui-Hui, Xiao, Miao-Miao, Zhang, Jing-Jing, Mao, Qiang, He, Bang-Jian, Tong, Pei-Jian“…BACKGROUND: Osteochondritis dissecans (OCD) is a rare disease of unclear cause characterized by subchondral bone damage and overlying cartilage defects. …”
Publicado 2021
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