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  1. 301
    “…In this initial 6-month open-label treatment period of a large, multiphase, relapse-prevention study, the efficacy and safety of paliperidone palmitate once-monthly (PP1M) injectable were evaluated in subjects with symptomatic SCA. …”
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    Paliperidone Palmitate Once-Monthly Injectable Treatment for Acute Exacerbations of Schizoaffective Disorder
  2. 302
    “…Nuclear genome duplication is normally restricted to once per cell division, but aberrant events that allow excess DNA replication (EDR) promote genomic instability and aneuploidy, both of which are characteristics of cancer development. …”
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    Identification of genes that are essential to restrict genome duplication to once per cell division
  3. 303
    “…BACKGROUND: Fluticasone furoate is a once-daily inhaled corticosteroid. This report provides an overview of safety and efficacy data that support the use of once-daily fluticasone furoate 100 μg or 200 μg in adult and adolescent asthma patients. …”
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    Integrated safety and efficacy analysis of once-daily fluticasone furoate for the treatment of asthma
  4. 304
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    Development of an oral once-weekly drug delivery system for HIV antiretroviral therapy
  5. 305
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    MAGIC: once upon a time in consent management—a FHIR(®) tale
  6. 306
    “…As compared with Restasis dosed twice per day, 0.1% CsA-MiDROPS dosed once per day demonstrated superiority. CONCLUSIONS: CsA-MiDROPS showed superior drug delivery and efficacy compared with other clinical formulations. …”
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    Once-Daily Cyclosporine-A-MiDROPS for Treatment of Dry Eye Disease
  7. 307
    “…However, no long-term evidence exists for radius bone density outcomes following treatment with once-weekly teriparatide in actual medical treatment. …”
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    Utility of radius bone densitometry for the treatment of osteoporosis with once-weekly teriparatide therapy
  8. 308
    “…It is unclear whether the two once-daily dosing non-vitamin K antagonist oral anticoagulants (NOACs), edoxaban and rivaroxaban, have similar effectiveness and safety in Asian patients with non-valvular atrial fibrillation (AF). …”
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    Comparison of Once-Daily Administration of Edoxaban and Rivaroxaban in Asian Patients with Atrial Fibrillation
  9. 309
    “…The only statistically significant difference among gabapentin-experienced and gabapentin-naïve groups was found in adverse event tolerability (65.78 ± 10.36 and 85.8 ± 10.14, p < 0.01). CONCLUSION: Once-daily dosing of gabapentin-extended release showed significant improvement in pain severity and functional status, with no difference found between gabapentin-experienced versus gabapentin-naïve patients.…”
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    The Effect of Once-Daily Gabapentin Extended Release Formulation in Patients With Postamputation Pain
  10. 310
    “…AIM: This post hoc analysis of a double‐blind (DB), randomized, placebo‐controlled, relapse‐prevention study evaluated the effects of paliperidone palmitate once‐every‐3‐months (PP3M) in a subpopulation of adults with early illness schizophrenia (duration ≤5 years) from a clinical trial. …”
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    Paliperidone palmitate once‐every‐3‐months in adults with early illness schizophrenia
  11. 311
    “…Based on pharmacokinetic modeling and simulations, dose regimens were recommended for subjects with impaired renal function to provide systemic amantadine exposure similar to subjects with normal renal function taking a once-daily extended-release amantadine tablet. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1007/s40263-019-00651-1) contains supplementary material, which is available to authorized users.…”
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    Effects of Renal Impairment on the Pharmacokinetics of Once-Daily Amantadine Extended-Release Tablets
  12. 312
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    The Virome of Cerebrospinal Fluid: Viruses Where We Once Thought There Were None
  13. 313
    por Iitake, Chie, Iitake, Kazuhiro
    Publicado 2019
    “…To evaluate the clinical effectiveness and safety profile of Pemafibrate, we have started with half dose once-daily administration. METHODS: Thirty-three patients with hypertriglyceridemia, triglyceride (TG) levels > 150 mg/dL, were treated with Pemafibrate (0.1 mg, once daily) from July 2018 to February 2019. …”
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    Half Dose Once-Daily Pemafibrate Effectively Improved Hypertriglyceridemia in Real Practice
  14. 314
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    Examining multiple cellular pathways at once using multiplex hextuple luciferase assaying
  15. 315
    “…Revefenacin 175 μg for nebulization provides an effective once-daily treatment option for patients with moderate to very severe COPD who require or prefer nebulized therapy.…”
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    Revefenacin: A Once-Daily, Long-Acting Bronchodilator For Nebulized Treatment Of COPD
  16. 316
    por Patel, Dhiren
    Publicado 2020
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    An overview of the once‐weekly GLP‐1 receptor agonists from the pharmacist’s perspective
  17. 317
    “…Eligible patients received once-monthly intramuscular injections of Risperidone ISM(®) (75 or 100 mg) or placebo for 12 weeks. …”
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    Efficacy and safety of once-monthly Risperidone ISM(®) in schizophrenic patients with an acute exacerbation
  18. 318
    “…One drop of the bilastine ophthalmic formulation was administered once daily in each eye of the subjects for 5 days. …”
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    Pharmacokinetics and Safety of a Bilastine Once-Daily, Preservative-Free, Ophthalmic Formulation
  19. 319
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    Ebola and COVID-19 in Democratic Republic of Congo: grappling with two plagues at once
  20. 320
    “…BACKGROUND AND OBJECTIVE: Once-daily injectable recombinant human growth hormone (GH) formulations (e.g. …”
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    Population Pharmacokinetics and Pharmacodynamics of Once-Daily Growth Hormone Norditropin(®) in Children and Adults
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