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  1. 381
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    Spotlight on grazoprevir–elbasvir once-daily combination and its potential in the treatment of hepatitis C
  2. 382
    “…OBJECTIVES: To evaluate the efficacy of once-weekly TPTD for patients with GIOP and inadequate response to bisphosphonates. …”
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    Once-weekly teriparatide improves glucocorticoid-induced osteoporosis in patients with inadequate response to bisphosphonates
  3. 383
    por Navarro, Jordi, Curran, Adrian
    Publicado 2016
    “…Furthermore, efficacy and safety of darunavir/cobicistat observed in phase III studies, including naïve and pretreated patients without darunavir-associated resistance mutations, are comparable to historical data of darunavir/ritonavir 800/100 mg once-daily formulation. Adverse events with darunavir/cobicistat are scarce and mild, and basically include skin reactions and gastrointestinal disturbances. …”
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    Profile of once-daily darunavir/cobicistat fixed-dose combination for the treatment of HIV/AIDS
  4. 384
    por Djambas Khayat, Claudia
    Publicado 2016
    “…Secondary prophylaxis therapy with 100 IU/kg nonacog alfa once weekly reduced annual bleeding rate by 89.4% relative to on-demand treatment. …”
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    Once-weekly prophylactic dosing of recombinant factor IX improves adherence in hemophilia B
  5. 385
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    ‘Once there is life, there is hope’ Ebola survivors' experiences, behaviours and attitudes in Sierra Leone, 2015
  6. 386
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    A dose increased once-weekly bortezomib-based combination therapy for multiple myeloma
  7. 387
    “…These evaluations, alongside demonstrated equivalence in total systemic exposure between IR and XR formulations, provided the basis for the regulatory approval of tofacitinib XR once daily by the US Food and Drug Administration.…”
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    Model‐Informed Development and Registration of a Once‐Daily Regimen of Extended‐Release Tofacitinib
  8. 388
    por Moriwaki, K., Mouri, M., Hagino, H.
    Publicado 2017
    “…Considering the advantage of once-yearly injection of zoledronic acid in persistence, zoledronic acid might be a cost-effective treatment option compared to once-weekly oral alendronate. …”
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    Cost-effectiveness analysis of once-yearly injection of zoledronic acid for the treatment of osteoporosis in Japan
  9. 389
    “…METHODS: FULFIL was a phase III, 24-week, randomized, double-blind, double-dummy, multicenter study comparing once-daily single inhaler triple therapy [fluticasone furoate/umeclidinium/vilanterol (FF/UMEC/VI)] 100 µg/62.5 µg/25 µg with twice-daily inhaled corticosteroid/long-acting β(2)-agonist therapy [budesonide/formoterol (BUD/FOR)] 400 µg/12 µg in patients with symptomatic COPD at risk of exacerbations. …”
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    Once-Daily Triple Therapy in Patients with COPD: Patient-Reported Symptoms and Quality of Life
  10. 390
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    Comparing i-gel and Ambu AuraOnce laryngeal mask airway in pediatric patients
  11. 391
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    14-3-3 Proteins in Plant Hormone Signaling: Doing Several Things at Once
  12. 392
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    Exenatide once weekly for smoking cessation: study protocol for a randomized clinical trial
  13. 393
    “…In 2008 the Ludwig Boltzmann Cluster Oncology (LBC ONC) was established on the basis of two previous Ludwig Boltzmann Institutes working in the field of hematology and cancer research. …”
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    Ludwig Boltzmann Cluster Oncology (LBC ONC): first 10 years and future perspectives
  14. 394
    “…In the present study, we investigated the effect on body composition, endocrine parameters, and memory performance of 8 weeks of once-daily administration of 160 IU in healthy men. …”
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    Metabolic and Cognitive Outcomes of Subchronic Once-Daily Intranasal Insulin Administration in Healthy Men
  15. 395
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    Cost-Effectiveness Of Once-Daily Single-Inhaler Triple Therapy In COPD: The IMPACT Trial
  16. 396
    “…OBJECTIVES: Once-weekly teriparatide (W-TPTD) is an effective drug for patients with osteoporosis; however, some patients discontinue W-TPTD owing to its adverse drug reactions (ADRs). …”
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    Effects of treatment interruption due to patient convenience on treatment of once a week teriparatide
  17. 397
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    Multimonth Dispensing of Antiretroviral Therapy Protects the Most Vulnerable From 2 Pandemics at Once
  18. 398
    “…Therefore, a comparative transcriptome profiling was conducted on once-bloomers and rebloomers from the same F(1) generation on six development stages, and the candidate genes associated with reblooming were identified. …”
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    To bloom once or more times: the reblooming mechanisms of Iris germanica revealed by transcriptome profiling
  19. 399
    por Hu, Guomin, Xu, Jun, Xu, Ling, Jin, Longmei
    Publicado 2020
    “…Age differed among and within genotypes in thrice, twice, and once positive women. The average age of HPV-free controls was 59.0 ± 7.2 yo, which is close to the median of average ages for thrice and twice positive women and is older than most average ages for once positive women. …”
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    The Prevalence of Thrice, Twice, and Once Human Papillomavirus DNA Positivity in Older Chinese Women
  20. 400
    por Trujillo, Jennifer
    Publicado 2020
    “…WHAT IS KNOWN AND OBJECTIVE: In recent years, glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) including once‐weekly (QW) formulations have been incorporated into type 2 diabetes (T2D) clinical guidelines, making it essential that pharmacists and healthcare professionals (HCPs) have a clear understanding of their safety profiles. …”
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    Safety and tolerability of once‐weekly GLP‐1 receptor agonists in type 2 diabetes
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