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521por Cremieux, Pierre Y., Fastenau, John M., Kosicki, George, Piech, Catherine T., Fendrick, A. Mark“…BACKGROUND: For individuals with chemotherapy-related anemia, the clinical effectiveness of epoetin alfa (EPO) dosed once weekly ([QW], 40,000 units per dose) has been demonstrated to be indistinguishable from that observed with thrice-weekly dosing ([TIW], 10,000 units per dose). …”
Publicado 2004
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522“…METHODS: Patients (N = 1,026) were randomly assigned once-daily (QD) desloratadine (2.5, 5, 7.5, 10, or 20 mg) for 2 weeks in a placebo-controlled, double-blind study. …”
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526“…AIMS: To assess treatment satisfaction and weight-related quality of life (QOL) in subjects with Type 2 diabetes treated with exenatide once weekly (QW) or twice daily (BID). METHODS: In this 52-week randomized, multi-centre, open-label study, 295 subjects managed with diet and exercise and/or oral glucose-lowering medications received either exenatide QW or BID during weeks 1–30; thereafter, subjects receiving exenatide BID were switched to exenatide QW, with 258 total subjects receiving exenatide QW during weeks 30–52. …”
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527
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528“…We found that oriII also needs SeqA for once-per-cell-cycle replication and, additionally, full methylation for efficient initiator binding. …”
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529por Anand, Inder S, Deswal, Anita, Kereiakes, Dean J, Purkayastha, Das, Zappe, Dion H“…BACKGROUND: The safety of once-daily (qd) dosing of valsartan in heart failure (HF) patients is not known. …”
Publicado 2010
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530por Tantilipikorn, Pongsakorn, Thanaviratananich, Sanguansak, Chusakul, Supinda, Benjaponpitak, Suwat, Fooanant, Supranee, Chintrakarn, Chalermchai, Jirapongsananuruk, Orathai, Visitsunthorn, Nualanong, Toler, Tom, Sutton, Laura, Wu, Wei, Lee, Laurie“…The safety findings showed FFNS 110 mcg once daily to be well tolerated.…”
Publicado 2010
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531por Taylor, Kristin, Gurney, Kate, Han, Jenny, Pencek, Richard, Walsh, Brandon, Trautmann, Michael“…BACKGROUND: The once-weekly (QW) formulation of the glucagon-like peptide-1 receptor agonist exenatide has been demonstrated to improve A1C, fasting plasma glucose (FPG), body weight, serum lipid profiles, and blood pressure in patients with type 2 diabetes through 52 weeks of treatment. …”
Publicado 2011
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533“…Nausea was the most frequent adverse event in this assessment period (intent-to-treat: exenatide once-weekly-only 5%; sitagliptin → exenatide once-weekly 11%; pioglitazone → exenatide once-weekly 10%). …”
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534“…Choice of therapy is increasingly influenced by treatment satisfaction and patient preference, with once-daily modified-release methylphenidate (MPH-MR) formulations offering clear benefits compared with immediate-release (IR) dosage forms. …”
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535por McClung, M. R., Miller, P. D., Brown, J. P., Zanchetta, J., Bolognese, M. A., Benhamou, C. L., Balske, A., Burgio, D. E., Sarley, J., McCullough, L. K., Recker, R. R.“…The bone mineral density response to a once weekly delayed-release formulation of risedronate given before or following breakfast was non-inferior to traditional immediate-release risedronate given daily before breakfast. …”
Publicado 2011
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536por D'Urzo, Anthony, Ferguson, Gary T, van Noord, Jan A, Hirata, Kazuto, Martin, Carmen, Horton, Rachael, Lu, Yimeng, Banerji, Donald, Overend, Tim“…BACKGROUND: NVA237 is a once-daily dry-powder formulation of the long-acting muscarinic antagonist glycopyrronium bromide in development for the treatment of chronic obstructive pulmonary disease (COPD). …”
Publicado 2011
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537“…To investigate this idea, we exposed C57Bl/6 mice once to cigarette smoke or to air (control) and prepared primary cultures of lung fibroblasts by microdissecting large airways (trachea, LAF), medium size airways (major bronchi, MAF) and parenchyma (PF). …”
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539por Kane, John M., Sanchez, Raymond, Zhao, Joan, Duca, Anna R., Johnson, Brian R., McQuade, Robert D., Eramo, Anna, Baker, Ross A., Peters-Strickland, Timothy“…OBJECTIVE: To report the design and preliminary results of a mirror-image study comparing total psychiatric hospitalisation rates pre- and post-switch to aripiprazole once-monthly, an extended release injectable solution. …”
Publicado 2013
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540“…CONCLUSIONS: Therapy with once-daily G-GR was as effective for treating pain associated with PHN in elderly patients as it was in younger patients. …”
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