Targeting Epstein–Barr virus oncoprotein LMP1-mediated glycolysis sensitizes nasopharyngeal carcinoma to radiation therapy

por Xiao, L, Hu, Z-y, Dong, X, Tan, Z, Li, W, Tang, M, Chen, L, Yang, L, Tao, Y, Jiang, Y, Li, J, Yi, B, Li, B, Fan, S, You, S, Deng, X, Hu, F, Feng, L, Bode, A M, Dong, Z, Sun, L-q, Cao, Y
Publicado 2014

DNA double-strand breaks cooperate with loss of Ink4 and Arf tumor suppressors to generate glioblastomas with frequent Met amplification

por Camacho, Cristel V., Todorova, Pavlina K., Gillam, Molly C., Tomimatsu, Nozomi, del Alcazar, Carlos R Gil, Ilcheva, Mariya, Mukherjee, Bipasha, McEllin, Brian, Vemireddy, Vamsidhara, Hatanpaa, Kimmo, Story, Michael D., Habib, Amyn A., Murty, Vundavalli V., Bachoo, Robert, Burma, Sandeep
Publicado 2014

Orthotopic models of pediatric brain tumors in zebrafish

por Eden, Christopher J., Ju, Bensheng, Murugesan, Mohankumar, Phoenix, Timothy, Nimmervoll, Birgit, Tong, Yiai, Ellison, David W., Finkelstein, David, Wright, Karen, Boulos, Nidal, Dapper, Jason, Thiruvenkatam, Radhika, Lessman, Charles, Taylor, Michael R., Gilbertson, Richard J.
Publicado 2014

Ubiquilin1 Represses Migration and Epithelial to Mesenchymal Transition of Human Non-small Cell Lung Cancer Cells

por Shah, Parag P., Lockwood, William W., Saurabh, Kumar, Kurlawala, Zimple, Shannon, Sean P., Waigel, Sabine, Zacharias, Wolfgang, Beverly, Levi J.
Publicado 2014

Two mature products of MIR-491 coordinate to suppress key cancer hallmarks in glioblastoma

por Li, Xia, Liu, Yuexin, Granberg, Kirsi J., Wang, Qinhao, Moore, Lynette M., Ji, Ping, Gumin, Joy, Sulman, Erik P., Calin, George A., Haapasalo, Hannu, Nykter, Matti, Shmulevich, Ilya, Fuller, Gregory N., Lang, Frederick F., Zhang, Wei
Publicado 2014

Phosphodiesterase 10A: a novel target for selective inhibition of colon tumor cell growth and β-catenin-dependent TCF transcriptional activity

por Li, Nan, Lee, Kevin, Xi, Yaguang, Zhu, Bing, Gary, Bernard D., Ramírez-Alcántara, Verónica, Gurpinar, Evrim, Canzoneri, Joshua C., Fajardo, Alexandra, Sigler, Sara, Piazza, John T., Chen, Xi, Andrews, Joel, Thomas, Meagan, Lu, Wenyan, Li, Yonghe, Laan, Danuel J., Moyer, Mary P., Russo, Suzanne, Eberhardt, Brian T., Yet, Larry, Keeton, Adam B., Grizzle, William E., Piazza, Gary A.
Publicado 2014

Nuclear PRAS40 couples the Akt/mTORC1 signaling axis to the RPL11-HDM2-p53 nucleolar stress response pathway

por Havel, Jonathan J., Li, Zenggang, Cheng, Dongmei, Peng, Junmin, Fu, Haian
Publicado 2014

Vimentin regulates lung cancer cell adhesion through a VAV2-Rac1 pathway to control focal adhesion kinase activity

por Havel, Lauren S., Kline, Erik R., Salgueiro, Alessandra M., Marcus, Adam I.
Publicado 2014

Activation of mTOR Pathway in Myeloid-derived Suppressor Cells Stimulates Cancer Cell Proliferation and Metastasis in lal−/− Mice

por Zhao, Ting, Du, Hong, Ding, Xinchun, Walls, Katlin, Yan, Cong
Publicado 2014

ZNF217, a candidate breast cancer oncogene amplified at 20q13, regulates expression of the ErbB3 receptor tyrosine kinase in breast cancer cells

por Krig, Sheryl R., Miller, Jamie K., Frietze, Seth, Beckett, Laurel A., Neve, Richard M., Farnham, Peggy J., Yaswen, Paul I., Sweeney, Colleen A.
Publicado 2010

Mammary glands exhibit molecular laterality and undergo left-right asymmetric ductal epithelial growth in MMTV-cNeu mice

por Robichaux, Jacqulyne P., Hallett, Robin M., Fuseler, John W., Hassell, John A., Ramsdell, Ann F.
Publicado 2014

PRKACA Mediates Resistance to HER2-Targeted Therapy in Breast Cancer Cells and Restores Anti-Apoptotic Signaling

por Moody, Susan E., Schinzel, Anna C., Singh, Shambhavi, Izzo, Francesca, Strickland, Matthew R., Luo, Leo, Thomas, Sapana R., Boehm, Jesse S., Kim, So Young, Wang, Zhigang C., Hahn, William C.
Publicado 2014

HSF1 REGULATION OF β-CATENIN IN MAMMARY CANCER CELLS THROUGH CONTROL OF HUR / ELAVL1 EXPRESSION

por Chou, Shiuh-Dih, Murshid, Ayesha, Eguchi, Takanori, Gong, Jianlin, Calderwood, Stuart K
Publicado 2014

Beta-Catenin Regulated ALDH1A1 is a Target in Ovarian Cancer Spheroids

por Condello, Salvatore, Morgan, Cynthia A., Nagdas, Sarbajeet, Cao, Liyun, Turek, John, Hurley, Thomas D., Matei, Daniela
Publicado 2014

Autophagy mediates HIF2α degradation and suppresses renal tumorigenesis

por Liu, Xian-De, Yao, Jun, Tripathi, Durga Nand, Ding, Zhiyong, Xu, Yi, Sun, Mianen, Zhang, Jiangwei, Bai, Shanshan, German, Peter, Hoang, Anh, Zhou, Lijun, Jonasch, Darius, Zhang, Xuesong, Conti, Claudio J., Efstathiou, Eleni, Tannir, Nizar M, Eissa, N. Tony, Mills, Gordon B., Walker, Cheryl Lyn, Jonasch, Eric
Publicado 2014

MutT Homolog 1 (MTH1) maintains multiple KRAS-driven pro-malignant pathways

por Patel, Asmita, Burton, Dominick G. A., Halvorsen, Katherine, Balkan, Wayne, Reiner, Teresita, Perez-Stable, Carlos, Cohen, Alexander, Munoz, Anisleidys, Giribaldi, Maria G., Singh, Samer, Robbins, David J., Nguyen, Dao M., Rai, Priyamvada
Publicado 2014

Ash2L enables P53–dependent apoptosis by favoring stable transcription pre–initiation complex formation on its pro-apoptotic target promoters

por Mungamuri, Sathish Kumar, Wang, Shaomeng, Manfredi, James J., Gu, Wei, Aaronson, Stuart A.
Publicado 2014

Actin filament-associated protein 1 is required for cSrc activity and secretory activation in the lactating mammary gland

por Cunnick, Jess M, Kim, Stephanie, Hadsell, James, Collins, Stephen, Cerra, Carmine, Reiser, Patti, Flynn, Daniel C, Cho, Youngjin
Publicado 2014

Loss of Epithelial p53 and αv Integrin Cooperate through Akt to Induce Squamous Cell Carcinoma yet Prevent Remodeling of the Tumor Microenvironment

por Savar, Aaron, Acin, Sergio, Gonzalez, Cassandra L., El-Sawy, Tarek, Mejia, Olga, Li, Zhongyou, Esmaeli, Bita, Lacy-Hulbert, Adam, El-Naggar, Adel, McCarty, Joseph H., Caulin, Carlos
Publicado 2014

The deubiquitylase Ataxin-3 restricts PTEN transcription in lung cancer cells

por Sacco, J J, Yau, T Y, Darling, S, Patel, V, Liu, H, Urbé, S, Clague, M J, Coulson, J M
Publicado 2014