Transcriptional repression of IFNβ1 by ATF2 confers melanoma resistance to therapy

por Lau, Eric, Sedy, John, Sander, Cindy, Shaw, Misa Austin, Feng, Yongmei, Scortegagna, Marzia, Claps, Giuseppina, Robinson, Steven, Cheng, Phil, Srivas, Rohith, Soonthornvacharin, Stephen, Ideker, Trey, Bosenberg, Marcus, Gonzalez, Réné, Robinson, William, Chanda, Sumit, Ware, Carl, Dummer, Reinhard, Hoon, Dave, Kirkwood, John M., Ronai, Ze'ev A
Publicado 2015

Cell growth density modulates cancer cell vascular invasion via Hippo pathway activity and CXCR2 signaling

por Sharif, Ghada M, Schmidt, Marcel O, Yi, Chunling, Hu, Zhangzhi, Haddad, Bassem R., Glasgow, Eric, Riegel, Anna T, Wellstein, Anton
Publicado 2015

The miR-200 family and the miR-183~96~182 cluster target Foxf2 to inhibit invasion and metastasis in lung cancers

por Kundu, Samrat T., Byers, Lauren A., Peng, David, Roybal, Jonathon D., Diao, Lixia, Wang, Jing, Tong, Pan, Creighton, Chad J., Gibbons, Don L.
Publicado 2015

XactMice: humanizing mouse bone marrow enables microenvironment reconstitution in a patient-derived xenograft model of head and neck cancer

por Morton, J. Jason, Bird, Gregory, Keysar, Stephen B., Astling, David P., Lyons, Traci R, Anderson, Ryan T., Glogowska, Magdalena J., Estes, Patricia, Eagles, Justin R., Le, Phuong N., Gan, Gregory, McGettigan, Brett, Fernandez, Pamela, Padilla-Just, Nuria, Varella-Garcia, Marileila, Song, John I., Bowles, Daniel W., Schedin, Pepper, Tan, Aik-Choon, Roop, Dennis R., Wang, Xiao-Jing, Refaeli, Yosef, Jimeno, Antonio
Publicado 2015

IGFBP2 potentiates nuclear EGFR-STAT3 signaling

por Chua, Corrine Yingxuan, Liu, Yuexin, Granberg, Kirsi J., Hu, Limei, Haapasalo, Hannu, Annala, Matti J., Cogdell, David E., Verploegen, Maartje, Moore, Lynette M., Fuller, Gregory N., Nykter, Matti, Cavenee, Webster K., Zhang, Wei
Publicado 2015

Mdm2 overexpression and p73 loss exacerbate genomic instability and dampen apoptosis resulting in B-cell lymphoma

por Riley, Maurisa F., You, M. James, Multani, Asha S., Lozano, Guillermina
Publicado 2015

Loss of the E3 ubiquitin ligase HACE1 results in enhanced Rac1 signaling contributing to breast cancer progression

por Goka, E T, Lippman, M E
Publicado 2015

Wnt addiction of genetically defined cancers reversed by PORCN inhibition

por Madan, B, Ke, Z, Harmston, N, Ho, S Y, Frois, A O, Alam, J, Jeyaraj, D A, Pendharkar, V, Ghosh, K, Virshup, I H, Manoharan, V, Ong, E H Q, Sangthongpitag, K, Hill, J, Petretto, E, Keller, T H, Lee, M A, Matter, A, Virshup, D M
Publicado 2016

Modulation of PKM alternative splicing by PTBP1 promotes gemcitabine resistance in pancreatic cancer cells

por Calabretta, Sara, Bielli, Pamela, Passacantilli, Ilaria, Pilozzi, Emanuela, Fendrich, Volker, Capurso, Gabriele, Delle Fave, Gianfranco, Sette, Claudio
Publicado 2015

Tumor-specific signaling to p53 is mimicked by Mdm2 inactivation in zebrafish: insights from mdm2 and mdm4 mutant zebrafish

por Chua, J S, Liew, H P, Guo, L, Lane, D P
Publicado 2015

The Matricellular Protein CCN1 Suppresses Hepatocarcinogenesis by Inhibiting Compensatory Proliferation

por Chen, Chih-Chiun, Kim, Ki-Hyun, Lau, Lester F.
Publicado 2015

Fibronectin induction abrogates the BRAF inhibitor response of BRAF V600E/PTEN-null melanoma cells

por Fedorenko, Inna V., Abel, Ethan V., Koomen, John M., Fang, Bin, Wood, Elizabeth R., Chen, Y. Ann, Fisher, Kate J., Iyengar, Sanjana, Dahlman, Kimberly B., Wargo, Jennifer A., Flaherty, Keith T., Sosman, Jeffrey A., Sondak, Vernon K., Messina, Jane L., Gibney, Geoffrey T., Smalley, Keiran S.M.
Publicado 2015

Regulation of osteosarcoma cell lung metastasis by the c-Fos/AP-1 target FGFR1

por Weekes, Daniel, Kashima, Takeshi G, Zandueta, Carolina, Perurena, Naiara, Thomas, David P, Sunters, Andrew, Vuillier, Céline, Bozec, Aline, El-Emir, Ethaar, Miletich, Isabelle, Patiño-Garcia, Ana, Lecanda, Fernando, Grigoriadis, Agamemnon E
Publicado 2015

YAP activation protects urothelial cell carcinoma from treatment-induced DNA damage

por Ciamporcero, Eric, Shen, He, Ramakrishnan, Swathi, Ku, Sheng Yu, Chintala, Sreenivasulu, Shen, Li, Adelaiye, Remi, Miles, Kiersten Marie, Ullio, Chiara, Pizzimenti, Stefania, Daga, Martina, Azabdaftari, Gissou, Attwood, Kris, Johnson, Candace, Zhang, Jianmin, Barrera, Giuseppina, Pili, Roberto
Publicado 2015

Regulation of Complement Dependent Cytotoxicity by TGF-β-induced Epithelial-Mesenchymal Transition

por Goswami, Moloy T., Reka, Ajaya Kumar, Kurapati, Himabindu, Kaza, Viritha, Chen, Jun, Standiford, Theodore J, Keshamouni, Venkateshwar G.
Publicado 2015

Disruption of Cytochrome c Oxidase Function Induces Warburg Effect and Metabolic Reprogramming

por Srinivasan, Satish, Guha, Manti, Dong, Dawei W, Whelan, Kelly A, Ruthel, Gordon, Uchikado, Yasuto, Natsugoe, Shoji, Nakagawa, Hiroshi, Avadhani, Narayan G.
Publicado 2015

Disruption of NCOA2 by recurrent fusion with LACTB2 in colorectal cancer

por Yu, J, Wu, W K K, Liang, Q, Zhang, N, He, J, Li, X, Zhang, X, Xu, L, Chan, M T V, Ng, S S M, Sung, J J Y
Publicado 2016

Development of secondary mutations in wild-type and mutant EZH2 alleles cooperates to confer resistance to EZH2 inhibitors

por Gibaja, V, Shen, F, Harari, J, Korn, J, Ruddy, D, Saenz-Vash, V, Zhai, H, Rejtar, T, Paris, C G, Yu, Z, Lira, M, King, D, Qi, W, Keen, N, Hassan, A Q, Chan, H M
Publicado 2016

SIRT3 regulates cellular iron metabolism and cancer growth by repressing iron regulatory protein 1

por Jeong, Seung Min, Lee, Jaewon, Schmidt, Paul J., Fleming, Mark D., Haigis, Marcia C.
Publicado 2014

MicroRNA regulons in tumor microenvironment

por Suzuki, H I, Katsura, A, Matsuyama, H, Miyazono, K
Publicado 2015