MOF maintains transcriptional programs regulating cellular stress response

por Sheikh, B N, Bechtel-Walz, W, Lucci, J, Karpiuk, O, Hild, I, Hartleben, B, Vornweg, J, Helmstädter, M, Sahyoun, A H, Bhardwaj, V, Stehle, T, Diehl, S, Kretz, O, Voss, A K, Thomas, T, Manke, T, Huber, T B, Akhtar, A
Publicado 2016

INPP4B is an oncogenic regulator in human colon cancer

por Guo, S T, Chi, M N, Yang, R H, Guo, X Y, Zan, L K, Wang, C Y, Xi, Y F, Jin, L, Croft, A, Tseng, H-Y, Yan, X G, Farrelly, M, Wang, F H, Lai, F, Wang, J F, Li, Y P, Ackland, S, Scott, R, Agoulnik, I U, Hondermarck, H, Thorne, R F, Liu, T, Zhang, X D, Jiang, C C
Publicado 2016

TBX2 represses PTEN in rhabdomyosarcoma and skeletal muscle

por Zhu, Bo, Zhang, Meiling, Williams, Elizabeth M., Keller, Charles, Mansoor, Atiya, Davie, Judith K.
Publicado 2015

Hypoxia-upregulated microRNA-630 targets Dicer, leading to increased tumor progression

por Rupaimoole, Rajesha, Ivan, Cristina, Yang, Da, Gharpure, Kshipra M., Wu, Sherry Y., Pecot, Chad V., Previs, Rebecca A., Nagaraja, Archana S., Armaiz-Pena, Guillermo N, McGuire, Michael, Pradeep, Sunila, Mangala, Lingegowda S., Rodriguez-Aguayo, Cristian, Huang, Li, Bar-Eli, Menashe, Zhang, Wei, Lopez-Berestein, Gabriel, Calin, George A., Sood, Anil K.
Publicado 2016

A Novel Association of Neuropilin-1 and MUC1 in Pancreatic Ductal Adenocarcinoma: Role in Induction of VEGF Signaling and Angiogenesis

por Zhou, Ru, Curry, Jennifer M, Roy, Lopamudra Das, Grover, Priyanka, Haider, Jamil, Moore, Laura J., Wu, Shu-ta, Kamesh, Anishaa, Yazdanifar, Mahboubeh, Ahrens, William A., Leung, TinChung, Mukherjee, Pinku
Publicado 2016

Disruption of insulin receptor function inhibits proliferation in endocrine resistant breast cancer cells

por Chan, Jie Ying, LaPara, Kelly, Yee, Douglas
Publicado 2016

HGF/Met and FOXM1 Form a Positive Feedback Loop and Render Pancreatic Cancer Cells Resistance to Met Inhibition and Aggressive Phenotypes

por Cui, Jiujie, Xia, Tian, Xie, Dacheng, Gao, Yong, Jia, Zhiliang, Wei, Daoyan, Wang, Liang, Huang, Suyun, Quan, Ming, Xie, Keping
Publicado 2016

A novel oncogenic BTK isoform is overexpressed in colon cancers and required for RAS-mediated transformation

por Grassilli, E, Pisano, F, Cialdella, A, Bonomo, S, Missaglia, C, Cerrito, M G, Masiero, L, Ianzano, L, Giordano, F, Cicirelli, V, Narloch, R, D'Amato, F, Noli, B, Ferri, G L, Leone, B E, Stanta, G, Bonin, S, Helin, K, Giovannoni, R, Lavitrano, M
Publicado 2016

Effects of Kras activation and Pten deletion alone or in combination on MUC1 biology and epithelial to mesenchymal transition in ovarian cancer

por Zhang, Lixin, Ma, Tianzhou, Brozick, Joan, Babalola, Kathlene, Budiu, Raluca, Tseng, George, Vlad, Anda M.
Publicado 2016

Targeting glutamine metabolism in multiple myeloma enhances BIM binding to BCL-2 eliciting synthetic lethality to venetoclax

por Bajpai, R, Matulis, SM, Wei, C, Nooka, AK, Von Hollen, HE, Lonial, S, Boise, LH, Shanmugam, M
Publicado 2015

Akt regulates Progesterone Receptor B dependent transcription and angiogenesis in endometrial cancer cells

por Lee, Irene I., Maniar, Kruti, Lydon, John P., Kim, J. Julie
Publicado 2016

RNA-binding motif protein 47 inhibits Nrf2 activity to suppress tumor growth in lung adenocarcinoma

por Sakurai, T, Isogaya, K, Sakai, S, Morikawa, M, Morishita, Y, Ehata, S, Miyazono, K, Koinuma, D
Publicado 2016

Osteocytic Connexin Hemichannels Suppress Breast Cancer Growth and Bone Metastasis

por Zhou, Jade Z., Riquelme, Manuel A., Gu, Sumin, Kar, Rekha, Gao, Xiaoli, Sun, LuZhe, Jiang, Jean X.
Publicado 2016

Cancer stem cell drugs target K-ras signaling in a stemness context

por Najumudeen, A K, Jaiswal, A, Lectez, B, Oetken-Lindholm, C, Guzmán, C, Siljamäki, E, Posada, I M D, Lacey, E, Aittokallio, T, Abankwa, D
Publicado 2016

The BET inhibitor JQ1 selectively impairs tumour response to hypoxia and downregulates CA9 and angiogenesis in triple negative breast cancer

por da Motta, L L, Ledaki, I, Purshouse, K, Haider, S, De Bastiani, M A, Baban, D, Morotti, M, Steers, G, Wigfield, S, Bridges, E, Li, J-L, Knapp, S, Ebner, D, Klamt, F, Harris, A L, McIntyre, A
Publicado 2017

Essential role of insulin-like growth factor 2 in resistance to histone deacetylase inhibitors

por Lee, Su-Chan, Min, Hye-Young, Jung, Hyun Jin, Park, Kwan Hee, Hyun, Seung Yeob, Cho, Jaebeom, Woo, Jong Kyu, Kwon, So Jung, Lee, Hyo-Jong, Lee, Ho-Young
Publicado 2016

Inhibition of FOXC2 restores epithelial phenotype and drug sensitivity in prostate cancer cells with stem-cell properties

por Paranjape, A N, Soundararajan, R, Werden, S J, Joseph, R, Taube, J H, Liu, H, Rodriguez-Canales, J, Sphyris, N, Wistuba, I, Miura, N, Dhillon, J, Mahajan, N, Mahajan, K, Chang, J T, Ittmann, M, Maity, S N, Logothetis, C, Tang, D G, Mani, S A
Publicado 2016

Myeloid translocation genes differentially regulate colorectal cancer programs

por Parang, Bobak, Bradley, Amber M., Mittal, Mukul K., Short, Sarah P., Thompson, Joshua J., Barrett, Caitlyn W., Naik, Rishi D., Bilotta, Anthony J., Washington, Mary K., Revetta, Frank L., Smith, Jesse J., Chen, Xi, Wilson, Keith T., Hiebert, Scott W., Williams, Christopher S.
Publicado 2016

The FEN1 L209P mutation interferes with long-patch base excision repair and induces cellular transformation

por Sun, H, He, L, Wu, H, Pan, F, Wu, X, Zhao, J, Hu, Z, Sekhar, C, Li, H, Zheng, L, Chen, H, Shen, B H, Guo, Z
Publicado 2017

A TGFβ-PRMT5-MEP50 Axis Regulates Cancer Cell Invasion through Histone H3 and H4 Arginine Methylation Coupled Transcriptional Activation and Repression

por Chen, Hongshan, Lorton, Benjamin, Gupta, Varun, Shechter, David
Publicado 2016