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  1. 69201
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    Increased expression of programmed cell death protein 1 on NK cells inhibits NK-cell-mediated anti-tumor function and indicates poor prognosis in digestive cancers
  2. 69202
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    Pyruvate dehydrogenase kinase 4 exhibits a novel role in the activation of mutant KRAS, regulating cell growth in lung and colorectal tumour cells
  3. 69203
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    Disrupting G6PD-mediated Redox homeostasis enhances chemosensitivity in colorectal cancer
  4. 69204
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    Elevated tumor LDLR expression accelerates LDL cholesterol-mediated breast cancer growth in mouse models of hyperlipidemia
  5. 69205
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    Fibroblast growth factor receptor is a mechanistic link between visceral adiposity and cancer
  6. 69206
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    Runx3 plays a critical role in restriction-point and defense against cellular transformation
  7. 69207
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    CUT-PCR: CRISPR-mediated, ultrasensitive detection of target DNA using PCR
  8. 69208
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    RCC2 is a novel p53 target in suppressing metastasis
  9. 69209
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    Loss of PRP4K drives anoikis resistance in part by dysregulation of epidermal growth factor receptor endosomal trafficking
  10. 69210
    por Zhang, F, Virshup, D M, Cheong, J K
    Publicado 2018
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    Oncogenic RAS-induced CK1α drives nuclear FOXO proteolysis
  11. 69211
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    mTORC2/AKT/HSF1/HuR constitute a feed-forward loop regulating Rictor expression and tumor growth in glioblastoma
  12. 69212
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    Oncogenic FLT3-ITD supports autophagy via ATF4 in acute myeloid leukemia
  13. 69213
    por Zhou, Y, Wang, L, Ban, X, Zeng, T, Zhu, Y, Li, M, Guan, X-Y, Li, Y
    Publicado 2018
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    DHRS2 inhibits cell growth and motility in esophageal squamous cell carcinoma
  14. 69214
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    SPARCL1 suppresses osteosarcoma metastasis and recruits macrophages by activation of canonical WNT/β-catenin signaling through stabilization of the WNT–receptor complex
  15. 69215
    “…Funding: This work was funded by FCT (PTDC/MEC-ONC/31384/2017).…”
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    SAT-351 CYP11B1 Is a Highly Accurate Marker of Malignancy in Functioning Adrenocortical Tumors
  16. 69216
    “…[Image: see text] In this study, a medical-grade poly(l-lactide-co-ε-caprolactone) (PLC) copolymer with a monomer ratio of l-lactide (L) to ε-caprolactone (C) of 70:30 mol % for use as an absorbable surgical suture was synthesized via ring-opening polymerization (ROP) using a novel soluble liquid tin(II) n-butoxide (Sn(OnC(4)H(9))(2)) as an initiator. In fiber fabrication, the process included copolymer melt extrusion with a minimal draw followed by sequential controlled hot-drawing and fixed-annealing steps to obtain oriented semicrystalline fibers with improved mechanical strength. …”
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    Development of an Antimicrobial-Coated Absorbable Monofilament Suture from a Medical-Grade Poly(l-lactide-co-ε-caprolactone) Copolymer
  17. 69217
    “…Health IT policymakers, including the Office of the National Coordinator for Health Information Technology (ONC), should explore strategies to expand the evidence base for real-world matching system performance, given the need for an evidence-based patient identity strategy.…”
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    Evaluation of real-world referential and probabilistic patient matching to advance patient identification strategy
  18. 69218
    “…Since available drugs have proven no benefits hereto for DIPG, it is fundamental to gain insights into the gene expression profile of DIPG patients and speed up the discovery of novel therapeutics for this dismal malignancy. Only the compound ONC201 was discovered to reduce DIPG tumors size in DIPG H3K27M mutated and now is in phase III clinical trials. …”
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    DIPG-27. DIFFUSE INTRINSIC PONTINE GLIOMA (DIPG) CHALLENGE: FROM GENE EXPRESSION PROFILE TO DRUG
  19. 69219
    por Tikoo, Minakshi
    Publicado 2012
    “…States that are participating in the projects funded under various Office of the National Coordinator for Health Information Technology (ONC) initiatives must focus on getting an accurate count of the physicians practising in their state, since their progress is being measured based on this key number.…”
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    Assessing the limitations of the existing physician directory for measuring electronic health record (EHR) adoption rates among physicians in Connecticut, USA: cross-sectional study
  20. 69220
    “…It was also presented to the officers of the Office of the National Coordinator (ONC) for HIT. All qualitative feedback was extremely positive and enthusiastic. …”
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    Improvement of workflow and processes to ease and enrich meaningful use of health information technology
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