EphA2 Promotes Infiltrative Invasion of Glioma Stem Cells in vivo through Crosstalk with Akt and Regulates Stem Properties

por Miao, Hui, Gale, Nickolas W., Guo, Hong, Qian, Juan, Petty, Aaron, Kaspar, James, Murphy, Andrew J., Valenzuela, David M., Yancopoulos, George, Hambardzumyan, Dolores, Lathia, Justin D., Rich, Jeremy N., Lee, Jeongwu, Wang, Bingcheng
Publicado 2014

A reciprocal role of prostate cancer on stromal DNA damage

por Banerjee, Jheelam, Mishra, Rajeev, Li, Xiaohong, Jackson, Roger S., Sharma, Adrija, Bhowmick, Neil A.
Publicado 2013

MEN1-tumorigenesis in the pituitary and pancreatic islet requires Cdk4 but not Cdk2

por Gillam, Mary P., Nimbalkar, Dipali, Sun, Limin, Christov, Konstantin, Ray, Dipankar, Kaldis, Philipp, Liu, Xianpeng, Kiyokawa, Hiroaki
Publicado 2014

The atypical ubiquitin ligase RNF31 stabilizes estrogen receptor α and modulates estrogen-stimulated breast cancer cell proliferation

por Zhu, J, Zhao, C, Kharman-Biz, A, Zhuang, T, Jonsson, P, Liang, N, Williams, C, Lin, C-Y, Qiao, Y, Zendehdel, K, Strömblad, S, Treuter, E, Dahlman-Wright, K
Publicado 2014

Interleukin 6 downregulates p53 expression and activity by stimulating ribosome biogenesis: a new pathway connecting inflammation to cancer

por Brighenti, E, Calabrese, C, Liguori, G, Giannone, F A, Trerè, D, Montanaro, L, Derenzini, M
Publicado 2014

Loss of breast epithelial marker hCLCA2 promotes epithelial to mesenchymal transition and indicates higher risk of metastasis

por Walia, Vijay, Yu, Yang, Cao, Deshou, Sun, Miao, McLean, Janel R., Hollier, Brett G., Cheng, Jiming, Mani, Sendurai A., Rao, Krishna, Premkumar, Louis, Elble, Randolph
Publicado 2011

Targeting autophagy overcomes Enzalutamide resistance in castration-resistant prostate cancer cells and improves therapeutic response in a xenograft model

por Nguyen, H G, Yang, J C, Kung, H-J, Shi, X-B, Tilki, D, Lara, P N, DeVere White, R W, Gao, A C, Evans, C P
Publicado 2014

MicroRNA-149 targets GIT1 to suppress integrin signaling and breast cancer metastasis

por Chan, S-H, Huang, W-C, Chang, J-W, Chang, K-J, Kuo, W-H, Wang, M-Y, Lin, K-Y, Uen, Y-H, Hou, M-F, Lin, C-M, Jang, T-H, Tu, C-W, Lee, Y-R, Lee, Y-H, Tien, M-T, Wang, L-H
Publicado 2014

Anti-apoptotic BCL-2 proteins govern cellular outcome following B-RAF(V600E) inhibition and can be targeted to reduce resistance

por Serasinghe, Madhavika N., Missert, Derek J., Asciolla, James J., Wieder, Shira Y., Podgrabinska, Simona, Izadmehr, Sudeh, Belbin, Gillian, Skobe, Mihaela, Chipuk, Jerry E.
Publicado 2014

Exosomal HIF1α supports invasive potential of nasopharyngeal carcinoma-associated LMP1-positive exosomes

por Aga, M, Bentz, G L, Raffa, S, Torrisi, M R, Kondo, S, Wakisaka, N, Yoshizaki, T, Pagano, J S, Shackelford, J
Publicado 2014

SOX2 regulates self-renewal and tumorigenicity of human melanoma-initiating cells

por Santini, R, Pietrobono, S, Pandolfi, S, Montagnani, V, D'Amico, M, Penachioni, J Y, Vinci, M C, Borgognoni, L, Stecca, B
Publicado 2014

Exome sequencing of pleuropulmonary blastoma reveals frequent biallelic loss of TP53 and two hits in DICER1 resulting in retention of 5p-derived miRNA hairpin loop sequences

por Pugh, T J, Yu, W, Yang, J, Field, A L, Ambrogio, L, Carter, S L, Cibulskis, K, Giannikopoulos, P, Kiezun, A, Kim, J, McKenna, A, Nickerson, E, Getz, G, Hoffher, S, Messinger, Y H, Dehner, L P, Roberts, C W M, Rodriguez-Galindo, C, Williams, G M, Rossi, C T, Meyerson, M, Hill, D A
Publicado 2014

Effects of Tumor Suppressor Lysyl Oxidase Propeptide on Prostate Cancer Xenograft Growth and Its Direct Interactions with DNA Repair Pathways

por Bais, Manish V., Ozdener, Gokhan Baris, Sonenshein, Gail E., Trackman, Philip C.
Publicado 2014

CXCL12-γ in Primary Tumors Drives Breast Cancer Metastasis

por Ray, Paramita, Stacer, Amanda C., Fenner, Joseph, Cavnar, Stephen P., Meguiar, Kaille, Brown, Martha, Luker, Kathryn E., Luker, Gary D.
Publicado 2014

The DEK oncogene promotes cellular proliferation through paracrine Wnt signaling in Ron receptor positive breast cancers

por Privette Vinnedge, Lisa M., Benight, Nancy M., Wagh, Purnima K., Pease, Nicholas A., Nashu, Madison A., Serrano-Lopez, Juana, Adams, Allie K., Cancelas, Jose A., Waltz, Susan E., Wells, Susanne I.
Publicado 2014

SOCS3-mediated regulation of inflammatory cytokines in PTEN and p53 inactivated triple negative breast cancer model

por Kim, Gwangil, Ouzounova, Maria, Quraishi, Ahmed A., Davis, April, Tawakkol, Nader, Clouthier, Shawn G., Malik, Fayaz, Paulson, Amanda K., D’Angelo, Rosemarie C., Korkaya, Sumeyye, Baker, Trenton L., Esen, Elif S., Prat, Aleix, Liu, Suling, Kleer, Celina G., Thomas, Dafydd G., Wicha, Max S., Korkaya, Hasan
Publicado 2014

MCT-1 expression and PTEN deficiency synergistically promote neoplastic multinucleation through the Src/p190B signaling activation

por Wu, M-H, Chen, Y-A, Chen, H-H, Chang, K-W, Chang, I-S, Wang, L-H, Hsu, H-L
Publicado 2014

The nuclear receptor NR2E1/TLX controls senescence

por O’Loghlen, Ana, Martin, Nadine, Krusche, Benjamin, Pemberton, Helen, Alonso, Marta M., Chandler, Hollie, Brookes, Sharon, Parrinello, Simona, Peters, Gordon, Gil, Jesús
Publicado 2014

TGF-β signaling alters the pattern of liver tumorigenesis induced by Pten inactivation

por Morris, Shelli M., Carter, Kelly T., Baek, Ji Yeon, Koszarek, Amanda, Yeh, Matthew M., Knoblaugh, Sue E., Grady, William M.
Publicado 2014

Fatty Acid Synthase inhibition engages a novel caspase-2 regulatory mechanism to induce ovarian cancer cell death

por Yang, Chih-Sheng, Matsuura, Kenkyo, Huang, Nai-Jia, Robeson, Alexander C., Huang, Bofu, Zhang, Liguo, Kornbluth, Sally
Publicado 2014