Inhibition of B-Raf/MEK/ERK signaling suppresses DR5 expression and impairs response of cancer cells to DR5-mediated apoptosis and T cell-induced killing

por Oh, You-Take, Deng, Jiusheng, Yue, Ping, Owonikoko, Taofeek K., Khuri, Fadlo R., Sun, Shi-Yong
Publicado 2015

Cables1 controls p21/Cip1 protein stability by antagonizing proteasome subunit alpha type 3

por Shi, Zhi, Li, Zenggang, Li, Zijian, Cheng, Kejun, Du, Yuhong, Fu, Haian, Khuri, Fadlo R.
Publicado 2014

Stable oncogenic silencing in vivo by programmable and targeted de novo DNA methylation in breast cancer

por Stolzenburg, S, Beltran, A S, Swift-Scanlan, T, Rivenbark, A G, Rashwan, R, Blancafort, P
Publicado 2015

LASP-1 – A nuclear hub for the UHRF1-DNMT1-G9a-Snail1 complex

por Duvall-Noelle, Nichole, Karwandyar, Ayub, Richmond, Ann, Raman, Dayanidhi
Publicado 2015

Induction of miRNA-181a by genotoxic treatments promotes chemotherapeutic resistance and metastasis in breast cancer

por Niu, Jixiao, Xue, Aimin, Chi, Yayun, Xue, Jingyan, Wang, Wei, Zhao, Ziqin, Fan, Meiyun, Yang, Chuan He, Shao, Zhi-ming, Pfeffer, Lawrence M., Wu, Jiong, Wu, Zhao-Hui
Publicado 2015

Histone deacetylase inhibitors prevent activation-induced cell death and promote anti-tumor immunity

por Cao, K, Wang, G, Li, W, Zhang, L, Wang, R, Huang, Y, Du, L, Jiang, J, Wu, C, He, X, Roberts, A I, Li, F, Rabson, A B, Wang, Y, Shi, Y
Publicado 2015

Iterative Tyrosine Phosphorylation Controls Non-canonical Domain Utilization in Crk

por Sriram, Ganapathy, Jankowski, Wojciech, Kasikara, Canan, Reichman, Charles, Saleh, Tamjeed, Nguyen, Khanh-Quynh, Li, Jing, Hornbeck, Peter, Machida, Kazuya, Liu, Tong, Li, Hong, Kalodimos, Charalampos G., Birge, Raymond B.
Publicado 2014

The WIP1 Oncogene Promotes Progression and Invasion of Aggressive Medulloblastoma Variants

por Buss, Meghan C., Remke, Marc, Lee, Juhyun, Gandhi, Khanjan, Schniederjan, Matthew J., Kool, Marcel, Northcott, Paul A., Pfister, Stefan M., Taylor, Michael D., Castellino, Robert C.
Publicado 2014

RNF126 promotes homologous recombination via regulation of E2F1-mediated BRCA1 expression

por Wang, Ying, Deng, Ou, Feng, Zhihui, Du, Zhanwen, Xiong, Xiahui, Lai, Jinzhi, Yang, Xiaosong, Xu, Mengyuan, Wang, Hongbing, Taylor, Derek, Yan, Chunhong, Chen, Ceshi, Difeo, Analisa, Ma, Zhefu, Zhang, Junran
Publicado 2015

H3K9me3 facilitates hypoxia-induced p53-dependent apoptosis through repression of APAK

por Olcina, M M, Leszczynska, K B, Senra, J M, Isa, N F, Harada, H, Hammond, E M
Publicado 2016

Regulation of c-Myc expression by the histone demethylase JMJD1A is essential for prostate cancer cell growth and survival

por Fan, Lingling, Peng, Guihong, Sahgal, Natasha, Fazli, Ladan, Gleave, Martin, Zhang, Yuji, Hussain, Arif, Qi, Jianfei
Publicado 2015

p73 engages A2B receptor signalling to prime cancer cells to chemotherapy-induced death

por Long, J S, Schoonen, P M, Graczyk, D, O'Prey, J, Ryan, K M
Publicado 2015

LZTFL1 suppresses lung tumorigenesis by maintaining differentiation of lung epithelial cells

por Wei, Q, Chen, Z-H, Wang, L, Zhang, T, Duan, L, Behrens, C, Wistuba, I I, Minna, J D, Gao, B, Luo, J-H, Liu, Z P
Publicado 2016

Glioma invasion mediated by the p75 neurotrophin receptor (p75(NTR)/CD271) requires regulated interaction with PDLIM1

por Ahn, B Y, Saldanha-Gama, R F G, Rahn, J J, Hao, X, Zhang, J, Dang, N-H, Alshehri, M, Robbins, S M, Senger, D L
Publicado 2016

Comprehensive translational control of tyrosine kinase expression by upstream open reading frames

por Wethmar, K, Schulz, J, Muro, E M, Talyan, S, Andrade-Navarro, M A, Leutz, A
Publicado 2016

Mitochondrial ATAD3A combines with GRP78 to regulate the WASF3 metastasis-promoting protein

por Teng, Yong, Ren, Xiaoou, Li, Honglin, Shull, Austin, Kim, Jaejik, Cowell, John K
Publicado 2015

Integrin α11β1 regulates cancer stromal stiffness and promotes tumorigenicity and metastasis in non-small cell lung cancer

por Navab, R, Strumpf, D, To, C, Pasko, E, Kim, K S, Park, C J, Hai, J, Liu, J, Jonkman, J, Barczyk, M, Bandarchi, B, Wang, Y H, Venkat, K, Ibrahimov, E, Pham, N-A, Ng, C, Radulovich, N, Zhu, C-Q, Pintilie, M, Wang, D, Lu, A, Jurisica, I, Walker, G C, Gullberg, D, Tsao, M-S
Publicado 2016

Differential in vivo tumorigenicity of diverse KRAS mutations in vertebrate pancreas: A comprehensive survey

por Park, Joon Tae, Johnson, Nicole, Liu, Shu, Levesque, Mathieu, Wang, Yue J., Ho, Hao, Huso, David, Maitra, Anirban, Parsons, Michael J., Prescott, Jason D., Leach, Steven D.
Publicado 2014

Differential association of STK11 and TP53 with KRAS mutation-associated gene expression, proliferation and immune surveillance in lung adenocarcinoma

por Schabath, Matthew B., Welsh, Eric A., Fulp, William J., Chen, Lu, Teer, Jamie K., Thompson, Zachary J., Engel, Brienne E., Xie, Mengyu, Berglund, Anders E., Creelan, Ben C., Antonia, Scott J., Gray, Jhanelle E., Eschrich, Steven, Chen, Dung-Tsa, Cress, W. Douglas, Haura, Eric B., Beg, Amer A.
Publicado 2015

A novel protein isoform of the RON tyrosine kinase receptor transforms human pancreatic duct epithelial cells

por Chakedis, Jeffery, French, Randall, Babicky, Michele, Jaquish, Dawn, Howard, Haleigh, Mose, Evangeline, Lam, Raymond, Holman, Patrick, Miyamoto, Jaclyn, Walterscheid, Zakk, Lowy, Andrew M.
Publicado 2015