CD146 is a novel marker for highly tumorigenic cells and a potential therapeutic target in malignant rhabdoid tumor

por Nodomi, S, Umeda, K, Saida, S, Kinehara, T, Hamabata, T, Daifu, T, Kato, I, Hiramatsu, H, Watanabe, K-i, Kuwahara, Y, Iehara, T, Adachi, S, Konishi, E, Nakahata, T, Hosoi, H, Heike, T
Publicado 2016

Olfactomedin 4 deletion induces colon adenocarcinoma in Apc(Min/+) mice

por Liu, W, Li, H, Hong, S-H, Piszczek, G P, Chen, W, Rodgers, G P
Publicado 2016

Downregulated miR-506 expression facilitates pancreatic cancer progression and chemoresistance via SPHK1/Akt/NF-κB signaling

por Li, J, Wu, H, Li, W, Yin, L, Guo, S, Xu, X, Ouyang, Y, Zhao, Z, Liu, S, Tian, Y, Tian, Z, Ju, J, Ni, B, Wang, H
Publicado 2016

Type I interferons exert anti-tumor effect via reversing immunosuppression mediated by mesenchymal stromal cells

por Shou, P, Chen, Q, Jiang, J, Xu, C, Zhang, J, Zheng, C, Jiang, M, Velletri, T, Cao, W, Huang, Y, Yang, Q, Han, X, Zhang, L, Wei, L, Rabson, A B, Chin, Y E, Wang, Y, Shi, Y
Publicado 2016

Breast Cancer Antiestrogen Resistance 3 (BCAR3) – p130(Cas) Interactions Promote Adhesion Disassembly and Invasion in Breast Cancer Cells

por Cross, Allison M., Wilson, Ashley L., Guerrero, Michael S., Thomas, Keena S., Bachir, Alexia I., Kubow, Kristopher E., Horwitz, A. Rick, Bouton, Amy H.
Publicado 2016

A causal link from ALK to hexokinase II overexpression and hyperactive glycolysis in EML4-ALK-positive lung cancer

por Ma, Yibao, Yu, Chunrong, Mohamed, Esraa M., Shao, Huanjie, Wang, Li, Sundaresan, Gobalakrishnan, Zweit, Jamal, Idowu, Michael, Fang, Xianjun
Publicado 2016

Pathogenic Helicobacter pylori Strains Translocate DNA and Activate TLR9 via the Cancer-Associated cag Type IV Secretion System

por Varga, Matthew G., Shaffer, Carrie L., Sierra, Johanna C., Suarez, Giovanni, Piazuelo, M. Blanca, Whitaker, Morgan E., Romero-Gallo, Judith, Krishna, Uma S., Delgado, Alberto, Gomez, Martin A., Good, James A. D., Almqvist, Fredrik, Skaar, Eric P., Correa, Pelayo, Wilson, Keith T., Hadjifrangiskou, Maria, Peek, Richard M.
Publicado 2016

The ErbB2ΔEx16 splice variant is a major oncogenic driver in breast cancer that promotes a pro-metastatic tumor microenvironment

por Turpin, Jason, Ling, Chen, Crosby, Erika J., Hartmann, Zachary C., Simond, Alexandra M., Chodosh, Lewis A., Rennhack, Jonathan P., Andrechek, Eran R., Ozcelik, John, Hallett, Michael, Mills, Gordon B., Cardiff, Robert D., Gray, Joe W., Griffith, Obi L., Muller, William J.
Publicado 2016

Characterization of activating mutations of NOTCH3 in T cell acute lymphoblastic leukemia and anti-leukemic activity of NOTCH3 inhibitory antibodies

por Bernasconi-Elias, Paula, Hu, Tiancen, Jenkins, David, Firestone, Brant, Gans, Sara, Kurth, Esther, Capodieci, Paola, Deplazes-Lauber, Joelle, Petropoulos, Konstantin, Thiel, Phillip, Ponsel, Dirk, Choi, Sung Hee, LeMotte, Peter, London, Anne, Goetcshkes, Margaret, Nolin, Erin, Jones, Michael D., Slocum, Kelly, Kluk, Michael J., Weinstock, David M., Christodoulou, Alexandra, Weinberg, Olga, Jaehrling, Jan, Ettenberg, Seth A., Buckler, Alan, Blacklow, Stephen C., Aster, Jon C., Fryer, Christy J.
Publicado 2016

Hsa-miR-24-3p Increases Nasopharyngeal Carcinoma Radiosensitivity by Targeting Both the 3’UTR and 5’UTR of Jab1/CSN5

por Wang, Sumei, Pan, Yunbao, Zhang, Rong, Xu, Tao, Wu, Wanyin, Wang, Chunhua, Huang, Hecheng, Calin, George A., Yang, Huiling, Claret, Francois X.
Publicado 2016

The C/EBPδ protein is stabilized by estrogen receptor α activity, inhibits SNAI2 expression, and associates with good prognosis in breast cancer

por Mendoza-Villanueva, Daniel, Balamurugan, Kuppusamy, Ali, H. Raza, Kim, Su-Ryun, Sharan, Shikha, Johnson, Randall C., Merchant, Anand S., Caldas, Carlos, Landberg, Göran, Sterneck, Esta
Publicado 2016

SUMOylation and SENP3 regulate STAT3 activation in head and neck cancer

por Zhou, Z, Wang, M, Li, J, Xiao, M, Chin, Y E, Cheng, J, Yeh, E T H, Yang, J, Yi, J
Publicado 2016

Tumour cell-derived exosomes endow mesenchymal stromal cells with tumour-promotion capabilities

por Lin, L Y, Du, L M, Cao, K, Huang, Y, Yu, P F, Zhang, L Y, Li, F Y, Wang, Y, Shi, Y F
Publicado 2016

Interleukin-17 promotes prostate cancer via MMP7-induced epithelial-to-mesenchymal transition

por Zhang, Q, Liu, S, Parajuli, KR, Zhang, W, Zhang, K, Mo, Z, Liu, J, Chen, Z, Yang, S, Wang, AR, Myers, L, You, Z
Publicado 2016

Base changes in tumour DNA have the power to reveal the causes and evolution of cancer

por Hollstein, M, Alexandrov, L B, Wild, C P, Ardin, M, Zavadil, J
Publicado 2017

The ERK–ZEB1 pathway mediates epithelial–mesenchymal transition in pemetrexed resistant lung cancer cells with suppression by vinca alkaloids

por Chiu, L-Y, Hsin, I-L, Yang, T-Y, Sung, W-W, Chi, J-Y, Chang, J T, Ko, J-L, Sheu, G-T
Publicado 2017

Amplification of R-spondin1 signaling induces granulosa cell fate defects and cancers in mouse adult ovary

por De Cian, M-C, Pauper, E, Bandiera, R, Vidal, V P I, Sacco, S, Gregoire, E P, Chassot, A-A, Panzolini, C, Wilhelm, D, Pailhoux, E, Youssef, S A, de Bruin, A, Teerds, K, Schedl, A, Gillot, I, Chaboissier, M-C
Publicado 2017

KRT19 directly interacts with β-catenin/RAC1 complex to regulate NUMB-dependent NOTCH signaling pathway and breast cancer properties

por Saha, S K, Choi, H Y, Kim, B W, Dayem, A A, Yang, G-M, Kim, K S, Yin, Y F, Cho, S-G
Publicado 2017

FOXC1 is involved in ERα silencing by counteracting GATA3 binding and is implicated in endocrine resistance

por Yu-Rice, Yi, Jin, Yanli, Han, Bingchen, Qu, Ying, Johnson, Jeffrey, Watanabe, Takaaki, Cheng, Long, Deng, Nan, Tanaka, Hisashi, Gao, Bowen, Liu, Zhenqiu, Sun, Zhijun, Bose, Shikha, Giuliano, Armando E., Cui, Xiaojiang
Publicado 2016

FGFR3-TACC3 fusion proteins act as naturally occurring drivers of tumor resistance by functionally substituting for EGFR/ERK signaling

por Daly, C, Castanaro, C, Zhang, W, Zhang, Q, Wei, Y, Ni, M, Young, T M, Zhang, L, Burova, E, Thurston, G
Publicado 2017