Downregulation of CXCL12 in mesenchymal stromal cells by TGFβ promotes breast cancer metastasis

por Yu, P F, Huang, Y, Xu, C L, Lin, L Y, Han, Y Y, Sun, W H, Hu, G H, Rabson, A B, Wang, Y, Shi, Y F
Publicado 2017

Rho-Associated Kinase 1 (ROCK1) inhibition is Synthetically Lethal with Von Hippel Lindau (VHL) Deficiency in Clear Cell Renal Cell Carcinoma (CC-RCC)

por Thompson, Jordan M., Nguyen, Quy H., Singh, Manpreet, Pavesic, Matthew W., Nesterenko, Irina, Nelson, Luke J., Liao, Alicia C., Razorenova, Olga V.
Publicado 2016

Addiction to the IGF2-ID1-IGF2 circuit for maintenance of the breast cancer stem-like cells

por Tominaga, K, Shimamura, T, Kimura, N, Murayama, T, Matsubara, D, Kanauchi, H, Niida, A, Shimizu, S, Nishioka, K, Tsuji, E-i, Yano, M, Sugano, S, Shimono, Y, Ishii, H, Saya, H, Mori, M, Akashi, K, Tada, K-i, Ogawa, T, Tojo, A, Miyano, S, Gotoh, N
Publicado 2017

The promotion of the transformation of quiescent gastric cancer stem cells by IL-17 and the underlying mechanisms

por Jiang, Y-X, Yang, S-W, Li, P-A, Luo, X, Li, Z-Y, Hao, Y-X, Yu, P-W
Publicado 2017

Multiplatform-based Molecular Subtypes of Non-Small Cell Lung Cancer

por Chen, Fengju, Zhang, Yiqun, Parra, Edwin, Rodriguez, Jaime, Behrens, Carmen, Akbani, Rehan, Lu, Yiling, Kurie, Jonathan, Gibbons, Don L., Mills, Gordon B., Wistuba, Ignacio I., Creighton, Chad J.
Publicado 2016

Epithelial-Mesenchymal Transition of Ovarian Cancer Cells Is Sustained by Rac1 through Simultaneous Activation of MEK1/2 and Src Signaling Pathways

por Fang, Dongdong, Chen, Huijun, Zhu, Jessica Y, Wang, Wei, Teng, Yong, Ding, Han-Fei, Jing, Qing, Su, Shi-Bing, Huang, Shuang
Publicado 2016

Lysine-specific demethylase KDM3A regulates ovarian cancer stemness and chemoresistance

por Ramadoss, S, Sen, S, Ramachandran, I, Roy, S, Chaudhuri, G, Farias-Eisner, R
Publicado 2017

ZEB1 Induces LOXL2-Mediated Collagen Stabilization and Deposition in the Extracellular Matrix to Drive Lung Cancer Invasion and Metastasis

por Peng, David H., Ungewiss, Christin, Tong, Pan, Byers, Lauren A., Wang, Jing, Canales, Jaime Rodriguez, Villalobos, Pamela A., Uraoka, Naohiro, Mino, Barbara, Behrens, Carmen, Wistuba, Ignacio I., Han, Richard I, Wanna, Charles A., Fahrenholtz, Monica, Grande-Allen, Kathryn Jane, Creighton, Chad J., Gibbons, Don L.
Publicado 2016

Inhibition of Polo-like kinase 1 during the DNA damage response is mediated through loss of Aurora A recruitment by Bora

por Bruinsma, W, Aprelia, M, García-Santisteban, I, Kool, J, Xu, Y J, Medema, R H
Publicado 2017

Transducin (β)-like 1 X-linked receptor 1 promotes gastric cancer progression via the ERK1/2 pathway

por Zhou, Q, Wang, X, Yu, Z, Wu, X, Chen, X, Li, J, Zhu, Z, Liu, B, Su, L
Publicado 2017

Acquired CDK6 amplification promotes breast cancer resistance to CDK4/6 inhibitors and loss of ER signaling and dependence

por Yang, C, Li, Z, Bhatt, T, Dickler, M, Giri, D, Scaltriti, M, Baselga, J, Rosen, N, Chandarlapaty, S
Publicado 2017

Stromal PTEN inhibits the expansion of mammary epithelial stem cells through Jagged-1

por Sizemore, GM, Balakrishnan, S, Hammer, AM, Thies, KA, Trimboli, AJ, Wallace, JA, Sizemore, ST, Kladney, RD, Woelke, SA, Yu, L, Fernandez, SA, Chakravarti, A, Leone, G, Ostrowski, MC
Publicado 2016

Aberrant activation of the PI3K/mTOR pathway promotes resistance to sorafenib in AML

por Lindblad, O, Cordero, E, Puissant, A, Macaulay, L, Ramos, A, Kabir, N N, Sun, J, Vallon-Christersson, J, Haraldsson, K, Hemann, M T, Borg, Å, Levander, F, Stegmaier, K, Pietras, K, Rönnstrand, L, Kazi, J U
Publicado 2016

Epidermal growth factor-induced ANGPTL4 enhances anoikis resistance and tumour metastasis in head and neck squamous cell carcinoma

por Liao, Y-H, Chiang, K-H, Shieh, J-M, Huang, C-R, Shen, C-J, Huang, W-C, Chen, B-K
Publicado 2017

Serglycin in tumor microenvironment promotes non-small cell lung cancer aggressiveness in a CD44-dependent manner

por Guo, J-Y, Hsu, H-S, Tyan, S-W, Li, F-Y, Shew, J-Y, Lee, W-H, Chen, J-Y
Publicado 2017

CIB1 contributes to oncogenic signalling by Ras via modulating the subcellular localisation of sphingosine kinase 1

por Zhu, Wenying, Gliddon, Briony L., Jarman, Kate E., Moretti, Paul A. B., Tin, Teresa, Parise, Leslie V., Woodcock, Joanna M., Powell, Jason A., Ruszkiewicz, Andrew, Pitman, Melissa R., Pitson, Stuart M.
Publicado 2016

Exosomes miR-126a released from MDSC induced by DOX treatment promotes lung metastasis

por Deng, Zhongbin, Rong, Yuan, Teng, Yun, Zhuang, Xiaoying, Samykutty, Abhilash, Mu, Jingyao, Zhang, Lifeng, Cao, Pengxiao, Yan, Jun, Miller, Donald, Zhang, Huang-Ge
Publicado 2016

Downregulation of miR-218 contributes to epithelial–mesenchymal transition and tumor metastasis in lung cancer by targeting Slug/ZEB2 signaling

por Shi, Z-M, Wang, L, Shen, H, Jiang, C-F, Ge, X, Li, D-M, Wen, Y-Y, Sun, H-R, Pan, M-H, Li, W, Shu, Y-Q, Liu, L-Z, Peiper, S C, He, J, Jiang, B-H
Publicado 2017

The Cdc42/Rac1 regulator CdGAP is a novel E-cadherin transcriptional co-repressor with Zeb2 in breast cancer

por He, Yi, Northey, Jason J., Pelletier, Ariane, Kos, Zuzana, Meunier, Liliane, Haibe-Kains, Benjamin, Mes-Masson, Anne-Marie, Côté, Jean-François, Siegel, Peter M., Lamarche-Vane, Nathalie
Publicado 2017

MicroRNA-383 located in frequently deleted chromosomal locus 8p22 regulates CD44 in prostate cancer

por Bucay, Nathan, Sekhon, Kirandeep, Yang, Thao, Majid, Shahana, Shahryari, Varahram, Hsieh, Christine, Mitsui, Yozo, Deng, Guoren, Tabatabai, Z. Laura, Yamamura, Soichiro, Calin, George A., Dahiya, Rajvir, Tanaka, Yuichiro, Saini, Sharanjot
Publicado 2016