Dynamic epigenetic regulation of the microRNA-200 family mediates epithelial and mesenchymal transitions in human tumorigenesis

por Davalos, V, Moutinho, C, Villanueva, A, Boque, R, Silva, P, Carneiro, F, Esteller, M
Publicado 2012

Lysophosphatidic acid and sphingosine-1-phosphate promote morphogenesis and block invasion of prostate cancer cells in three-dimensional organotypic models

por Härmä, V, Knuuttila, M, Virtanen, J, Mirtti, T, Kohonen, P, Kovanen, P, Happonen, A, Kaewphan, S, Ahonen, I, Kallioniemi, O, Grafström, R, Lötjönen, J, Nees, M
Publicado 2012

Hic-5 Controls BMP4 Responses in Prostate Cancer Cells through Interacting with Smads 1, 5 and 8

por Shola, Dorjee T.N., Wang, Hui, Wahdan-Alaswad, Reema, Danielpour, David
Publicado 2011

CXCL13 Activation of c-Myc Induce RANK Ligand Expression in Stromal/Preosteoblast Cells in the Oral Squamous Cell Carcinoma Tumor-Bone Microenvironment

por Sambandam, Yuvaraj, Sundaram, Kumaran, Liu, Angen, Kirkwood, Keith L., Ries, William L., Reddy, Sakamuri V.
Publicado 2012

FOXA1 Represses the Molecular Phenotype of Basal Breast Cancer Cells

por Bernardo, Gina M., Bebek, Gurkan, Ginther, Charles L., Sizemore, Steven T., Lozada, Kristen L., Miedler, John D., Anderson, Lee A., Godwin, Andrew K., Abdul-Karim, Fadi W., Slamon, Dennis J., Keri, Ruth A.
Publicado 2012

Mapping the regulatory sequences controlling 93 breast cancer-associated miRNA genes leads to the identification of two functional promoters of the Hsa-mir-200b cluster, methylatio...

por Wee, E J H, Peters, K, Nair, S S, Hulf, T, Stein, S, Wagner, S, Bailey, P, Lee, S Y, Qu, W J, Brewster, B, French, J D, Dobrovic, A, Francis, G D, Clark, S J, Brown, M A
Publicado 2012

C. elegans FOG-3/Tob can either promote or inhibit germline proliferation, depending on gene dosage and genetic context

por Snow, Joshua J., Lee, Myon-Hee, Verheyden, Jamie, Kroll-Conner, Peggy L., Kimble, Judith
Publicado 2012

Modulation of Neuroblastoma Disease Pathogenesis By An Extensive Network of Epigenetically Regulated MicroRNAs

por Das, Sudipto, Bryan, Kenneth, Buckley, Patrick G, Piskareva, Olga, Bray, Isabella M, Foley, Niamh, Ryan, Jacqueline, Lynch, Jennifer, Creevey, Laura, Fay, Joanna, Prenter, Suzanne, Koster, Jan, van Sluis, Peter, Versteeg, Rogier, Eggert, Angelika, Schulte, Johannes H, Schramm, Alexander, Mesdagh, Pieter, Vandesompele, Jo, Speleman, Frank, Stallings, Raymond L
Publicado 2012

Transcriptional Regulation of the GPX1 Gene by TFAP2C and Aberrant CpG Methylation in Human Breast Cancer

por Kulak, Mikhail V., Cyr, Anthony R., Woodfield, George W., Bogachek, Maria, Spanheimer, Philip M., Li, Tiandao, Price, David H., Domann, Frederick E., Weigel, Ronald J.
Publicado 2012

Targeting Stat3 and Smad7 to restore TGF-β cytostatic regulation of tumor cells in vitro and in vivo

por Luwor, R B, Baradaran, B, Taylor, L E, Iaria, J, Nheu, T V, Amiry, N, Hovens, C M, Wang, B, Kaye, A H, Zhu, H-J
Publicado 2013

Truncated p110 ERBB2 induces mammary epithelial cell migration, invasion and orthotopic xenograft formation, and is associated with loss of phosphorylated STAT5

por Ward, T M, Iorns, E, Liu, X, Hoe, N, Kim, P, Singh, S, Dean, S, Jegg, A-M, Gallas, M, Rodriguez, C, Lippman, M, Landgraf, R, Pegram, M D
Publicado 2013

Epigenetic screen identifies genotype- specific promoter DNA methylation and oncogenic potential of CHRNB4

por Scherf, David B, Sarkisyan, Narek, Jacobsson, Hanna, Claus, Rainer, Bermejo, Justo L, Peil, Barbara, Gu, Lei, Muley, Thomas, Meister, Michael, Dienemann, Hendrik, Plass, Christoph, Risch, Angela
Publicado 2012

Different APC genotypes in proximal and distal sporadic colorectal cancers suggest distinct WNT/β-catenin signalling thresholds for tumourigenesis

por Christie, M, Jorissen, R N, Mouradov, D, Sakthianandeswaren, A, Li, S, Day, F, Tsui, C, Lipton, L, Desai, J, Jones, I T, McLaughlin, S, Ward, R L, Hawkins, N J, Ruszkiewicz, A R, Moore, J, Burgess, A W, Busam, D, Zhao, Q, Strausberg, R L, Simpson, A J, Tomlinson, I P M, Gibbs, P, Sieber, O M
Publicado 2013

miR-30d, miR-181a and miR-199a-5p cooperatively suppress the endoplasmic reticulum chaperone and signaling regulator GRP78 in cancer

por Su, S-F, Chang, Y-W, Andreu-Vieyra, C, Fang, J Y, Yang, Z, Han, B, Lee, A S, Liang, G
Publicado 2013

Long interspersed element-1 is differentially regulated by food-borne carcinogens via the aryl hydrocarbon receptor

por Okudaira, N, Okamura, T, Tamura, M, Iijma, K, Goto, M, Matsunaga, A, Ochiai, M, Nakagama, H, Kano, S, Fujii-Kuriyama, Y, Ishizaka, Y
Publicado 2013

Non-canonical Notch signaling activates IL-6/JAK/STAT signaling in breast tumor cells and is controlled by p53 and IKKα/IKKβ

por Jin, S, Mutvei, A P, Chivukula, I V, Andersson, E R, Ramsköld, D, Sandberg, R, Lee, K L, Kronqvist, P, Mamaeva, V, Östling, P, Mpindi, J-P, Kallioniemi, O, Screpanti, I, Poellinger, L, Sahlgren, C, Lendahl, U
Publicado 2013

BAG-1 suppresses expression of the key regulatory cytokine transforming growth factor beta [TGF-β1] in colorectal tumour cells

por Skeen, Victoria R., Collard, Tracey J., Southern, Samantha L., Greenhough, Alexander, Hague, Angela, Townsend, Paul, Paraskeva, Christos, Williams, Ann C.
Publicado 2012

Aberrant Mer receptor tyrosine kinase expression contributes to leukemogenesis in acute myeloid leukemia

por Lee-Sherick, A B, Eisenman, K M, Sather, S, McGranahan, A, Armistead, P M, McGary, C S, Hunsucker, S A, Schlegel, J, Martinson, H, Cannon, C, Keating, A K, Earp, H S, Liang, X, DeRyckere, D, Graham, D K
Publicado 2013

Prolactin suppresses a progestin-induced CK5-positive cell population in luminal breast cancer through inhibition of progestin-driven BCL6 expression

por Sato, Takahiro, Tran, Thai H., Peck, Amy R., Girondo, Melanie A., Liu, Chengbao, Goodman, Chelain R., Neilson, Lynn M., Freydin, Boris, Chervoneva, Inna, Hyslop, Terry, Kovatich, Albert J., Hooke, Jeffrey A., Shriver, Craig D., Fuchs, Serge Y., Rui, Hallgeir
Publicado 2013

Regulation of several androgen-induced genes through the repression of the miR-99a/let-7c/miR-125b-2 miRNA cluster in prostate cancer cells

por Sun, Dandan, Layer, Ryan, Mueller, Adam C., Cichewicz, Magdalena A., Negishi, Masamitsu, Paschal, Bryce M., Dutta, Anindya
Publicado 2013