MiRNA-621 sensitizes breast cancer to chemotherapy by suppressing FBXO11 and enhancing p53 activity

por Xue, J, Chi, Y, Chen, Y, Huang, S, Ye, X, Niu, J, Wang, W, Pfeffer, L M, Shao, Z-m, Wu, Z-H, Wu, J
Publicado 2016

OTUB1 inhibits the ubiquitination and degradation of FOXM1 in breast cancer and epirubicin resistance

por Karunarathna, U, Kongsema, M, Zona, S, Gong, C, Cabrera, E, Gomes, A R, Man, E P S, Khongkow, P, Tsang, J W-H, Khoo, U-S, Medema, R H, Freire, R, Lam, E W-F
Publicado 2016

SETD2 loss-of-function promotes renal cancer branched evolution through replication stress and impaired DNA repair

por Kanu, N, Grönroos, E, Martinez, P, Burrell, R A, Yi Goh, X, Bartkova, J, Maya-Mendoza, A, Mistrík, M, Rowan, A J, Patel, H, Rabinowitz, A, East, P, Wilson, G, Santos, C R, McGranahan, N, Gulati, S, Gerlinger, M, Birkbak, N J, Joshi, T, Alexandrov, L B, Stratton, M R, Powles, T, Matthews, N, Bates, P A, Stewart, A, Szallasi, Z, Larkin, J, Bartek, J, Swanton, C
Publicado 2015

Oncogenic KRAS signalling promotes the Wnt/β-catenin pathway through LRP6 in colorectal cancer

por Lemieux, E, Cagnol, S, Beaudry, K, Carrier, J, Rivard, N
Publicado 2015

Overexpression of miR-214-3p in Esophageal Squamous Cancer Cells Enhances Sensitivity to Cisplatin by Targeting Survivin Directly and Indirectly Through CUG-BP1

por Phatak, Pornima, Byrnes, Kimberly A., Mansour, Daniel, Liu, Lan, Cao, Shan, Li, Ruiyun, Rao, Jaladanki N., Turner, Douglas J., Wang, Jian-Ying, Donahue, James M.
Publicado 2015

Anti-angiogenic pathway associations of the 3p21.3 mapped BLU gene in nasopharyngeal carcinoma

por Cheng, Y, Ho, R L K Y, Chan, K C, Kan, R, Tung, E, Lung, H L, Yau, W L, Cheung, A K L, Ko, J M Y, Zhang, Z F, Luo, D Z, Feng, Z B, Chen, S, Guan, X Y, Kwong, D, Stanbridge, E J, Lung, M L
Publicado 2015

DACT2 is a functional tumor suppressor through inhibiting Wnt/β-catenin pathway and associated with poor survival in colon cancer

por Wang, S, Dong, Y, Zhang, Y, Wang, X, Xu, L, Yang, S, Li, X, Dong, H, Xu, L, Su, L, Ng, S S M, Chang, Z, Sung, J J, Zhang, X, Yu, J
Publicado 2015

Steroid induction of therapy-resistant cytokeratin-5-positive cells in estrogen receptor-positive breast cancer through a BCL6-dependent mechanism

por Goodman, C R, Sato, T, Peck, A R, Girondo, M A, Yang, N, Liu, C, Yanac, A F, Kovatich, A J, Hooke, J A, Shriver, C D, Mitchell, E P, Hyslop, T, Rui, H
Publicado 2016

Estrogen promotes the brain metastatic colonization of triple negative breast cancer cells via an astrocyte-mediated paracrine mechanism

por Sartorius, Carol A., Hanna, Colton T., Gril, Brunilde, Cruz, Hazel, Serkova, Natalie J., Huber, Kendra M., Kabos, Peter, Schedin, Troy B., Borges, Virginia F., Steeg, Patricia S., Cittelly, Diana M.
Publicado 2015

Biodegradable interstitial release polymer loading a novel small molecule targeting Axl receptor tyrosine kinase and reducing brain tumour migration and invasion

por Yen, S-Y, Chen, S-R, Hsieh, J, Li, Y-S, Chuang, S-E, Chuang, H-M, Huang, M-H, Lin, S-Z, Harn, H-J, Chiou, T-W
Publicado 2016

AP2α controls the dynamic balance between miR-126&126* and miR-221&222 during melanoma progression

por Felli, N, Errico, M C, Pedini, F, Petrini, M, Puglisi, R, Bellenghi, M, Boe, A, Felicetti, F, Mattia, G, De Feo, A, Bottero, L, Tripodo, C, Carè, A
Publicado 2016

p19(Arf) is required for the cellular response to chronic DNA damage

por Bieging-Rolett, Kathryn T., Johnson, Thomas M., Brady, Colleen A., Beaudry, Veronica G., Pathak, Navneeta, Han, Shuo, Attardi, Laura D.
Publicado 2016

HER2 induced EMT and tumorigenicity in breast epithelial progenitor cells is inhibited by coexpression of EGFR

por Ingthorsson, S, Andersen, K, Hilmarsdottir, B, Maelandsmo, G M, Magnusson, M K, Gudjonsson, T
Publicado 2016

Oncogenic CARMA1 couples NF-κB and β-catenin signaling in diffuse large B-cell lymphomas

por Bognar, M K, Vincendeau, M, Erdmann, T, Seeholzer, T, Grau, M, Linnemann, J R, Ruland, J, Scheel, C H, Lenz, P, Ott, G, Lenz, G, Hauck, S M, Krappmann, D
Publicado 2016

Enhanced MAPK signaling drives ETS1-mediated induction of miR-29b leading to downregulation of TET1 and changes in epigenetic modifications in a subset of lung SCC

por Taylor, M A, Wappett, M, Delpuech, O, Brown, H, Chresta, C M
Publicado 2016

Topoisomerase IIα mediates TCF-dependent epithelial–mesenchymal transition in colon cancer

por Zhou, Q, Abraham, A D, Li, L, Babalmorad, A, Bagby, S, Arcaroli, J J, Hansen, R J, Valeriote, F A, Gustafson, D L, Schaack, J, Messersmith, W A, LaBarbera, D V
Publicado 2016

HOXA5 determines cell fate transition and impedes tumor initiation and progression in breast cancer through regulation of E-cadherin and CD24

por Teo, Wei Wen, Merino, Vanessa F., Cho, Soonweng, Korangath, Preethi, Liang, Xiaohui, Wu, Ren-chin, Neumann, Neil M., Ewald, Andrew J., Sukumar, Saraswati
Publicado 2016

A multidimensional network approach reveals microRNAs as determinants of the mesenchymal colorectal cancer subtype

por Fessler, E, Jansen, M, De Sousa E Melo, F, Zhao, L, Prasetyanti, P R, Rodermond, H, Kandimalla, R, Linnekamp, J F, Franitza, M, van Hooff, S R, de Jong, J H, Oppeneer, S C, van Noesel, C J M, Dekker, E, Stassi, G, Wang, X, Medema, J P, Vermeulen, L
Publicado 2016

Functional Interaction of Histone Deacetylase 5 (HDAC5) and Lysine-specific Demethylase 1 (LSD1) Promotes Breast Cancer Progression

por Cao, Chunyu, Vasilatos, Shauna N., Bhargava, Rohit, Fine, Jeffrey L., Oesterreich, Steffi, Davidson, Nancy E., Huang, Yi
Publicado 2016

MicroRNA-101 regulated transcriptional modulator SUB1 plays a role in prostate cancer

por Chakravarthi, B V S K, Goswami, M T, Pathi, S S, Robinson, A D, Cieślik, M, Chandrashekar, D S, Agarwal, S, Siddiqui, J, Daignault, S, Carskadon, S L, Jing, X, Chinnaiyan, A M, Kunju, L P, Palanisamy, N, Varambally, S
Publicado 2016