Molecular analysis of urothelial cancer cell lines for modeling tumor biology and drug response

por Nickerson, M L, Witte, N, Im, K M, Turan, S, Owens, C, Misner, K, Tsang, S X, Cai, Z, Wu, S, Dean, M, Costello, J C, Theodorescu, D
Publicado 2017

Integrated genomic analysis of colorectal cancer progression reveals activation of EGFR through demethylation of the EREG promoter

por Qu, X, Sandmann, T, Frierson, H, Fu, L, Fuentes, E, Walter, K, Okrah, K, Rumpel, C, Moskaluk, C, Lu, S, Wang, Y, Bourgon, R, Penuel, E, Pirzkall, A, Amler, L, Lackner, M R, Tabernero, J, Hampton, G M, Kabbarah, O
Publicado 2016

Genomic modelling of the ESR1 Y537S mutation for evaluating function and new therapeutic approaches for metastatic breast cancer

por Harrod, A, Fulton, J, Nguyen, V T M, Periyasamy, M, Ramos-Garcia, L, Lai, C-F, Metodieva, G, de Giorgio, A, Williams, R L, Santos, D B, Gomez, P J, Lin, M-L, Metodiev, M V, Stebbing, J, Castellano, L, Magnani, L, Coombes, R C, Buluwela, L, Ali, S
Publicado 2017

p62/SQSTM1 enhances breast cancer stem-like properties by stabilizing MYC mRNA

por Xu, L-Z, Li, S-S, Zhou, W, Kang, Z-J, Zhang, Q-X, Kamran, M, Xu, J, Liang, D-P, Wang, C-L, Hou, Z-J, Wan, X-B, Wang, H-J, Lam, E W-F, Zhao, Z-W, Liu, Q
Publicado 2017

Heterozygous p53(V172F) mutation in cisplatin-resistant human tumor cells promotes MDM4 recruitment and decreases stability and transactivity of p53

por Xie, Xiaolei, Lozano, Guillermina, Siddik, Zahid H.
Publicado 2016

Collapsin response mediator protein-1 (CRMP1) acts as an invasion and metastasis suppressor of prostate cancer via its suppression of epithelial–mesenchymal transition and remodeli...

por Cai, G, Wu, D, Wang, Z, Xu, Z, Wong, K-B, Ng, C-F, Chan, F L, Yu, S
Publicado 2017

Synergistic functions of E2F7 and E2F8 are critical to suppress stress-induced skin cancer

por Thurlings, I, Martínez-López, L M, Westendorp, B, Zijp, M, Kuiper, R, Tooten, P, Kent, L N, Leone, G, Vos, H J, Burgering, B, de Bruin, A
Publicado 2017

Protein arginine methyltransferase 5 functions as an epigenetic activator of the androgen receptor to promote prostate cancer cell growth

por Deng, X, Shao, G, Zhang, H-T, Li, C, Zhang, D, Cheng, L, Elzey, B D, Pili, R, Ratliff, T L, Huang, J, Hu, C-D
Publicado 2017

Systematic and functional characterization of novel androgen receptor variants arising from alternative splicing in the ligand-binding domain

por Uo, T, Dvinge, H, Sprenger, C C, Bradley, R K, Nelson, P S, Plymate, S R
Publicado 2017

DLX1 acts as a crucial target of FOXM1 to promote ovarian cancer aggressiveness by enhancing TGF-β/SMAD4 signaling

por Chan, D W, Hui, W W Y, Wang, J J, Yung, M M H, Hui, L M N, Qin, Y, Liang, R R, Leung, T H Y, Xu, D, Chan, K K L, Yao, K-M, Tsang, B K, Ngan, H Y S
Publicado 2017

Targeting the hedgehog transcription factors GLI1 and GLI2 restores sensitivity to vemurafenib-resistant human melanoma cells

por Faião-Flores, F, Alves-Fernandes, D K, Pennacchi, P C, Sandri, S, Vicente, A L S A, Scapulatempo-Neto, C, Vazquez, V L, Reis, R M, Chauhan, J, Goding, C R, Smalley, K S, Maria-Engler, S S
Publicado 2017

A pre-neoplastic epigenetic field defect in HCV-infected liver at transcription factor binding sites and polycomb targets

por Wijetunga, N A, Pascual, M, Tozour, J, Delahaye, F, Alani, M, Adeyeye, M, Wolkoff, A W, Verma, A, Greally, J M
Publicado 2017

The hot-spot p53R172H mutant promotes formation of giant spermatogonia triggered by DNA damage

por Xue, Y, Raharja, A, Sim, W, Wong, E S M, Rahmat, S A B, Lane, D P
Publicado 2017

Wwox–Brca1 interaction: role in DNA repair pathway choice

por Schrock, M S, Batar, B, Lee, J, Druck, T, Ferguson, B, Cho, J H, Akakpo, K, Hagrass, H, Heerema, N A, Xia, F, Parvin, J D, Aldaz, C M, Huebner, K
Publicado 2017

DNA demethylation induces SALL4 gene re-expression in subgroups of hepatocellular carcinoma associated with Hepatitis B or C virus infection

por Fan, Huitao, Cui, Zhibin, Zhang, Hao, Kailasam Mani, Saravana Kumar, Diab, Ahmed, Lefrancois, Lydie, Fares, Nadim, Merle, Philippe, Andrisani, Ourania
Publicado 2016

Detecting intratumoral heterogeneity of EGFR activity by liposome-based in vivo transfection of a fluorescent biosensor

por Weitsman, G, Mitchell, N J, Evans, R, Cheung, A, Kalber, T L, Bofinger, R, Fruhwirth, G O, Keppler, M, Wright, Z V F, Barber, P R, Gordon, P, de Koning, T, Wulaningsih, W, Sander, K, Vojnovic, B, Ameer-Beg, S, Lythgoe, M, Arnold, J N, Årstad, E, Festy, F, Hailes, H C, Tabor, A B, Ng, T
Publicado 2017

A redox state-dictated signalling pathway deciphers the malignant cell specificity of CD40-mediated apoptosis

por Dunnill, C J, Ibraheem, K, Mohamed, A, Southgate, J, Georgopoulos, N T
Publicado 2017

Neuropilin-1 is upregulated in the adaptive response of prostate tumors to androgen-targeted therapies and is prognostic of metastatic progression and patient mortality

por Tse, B W C, Volpert, M, Ratther, E, Stylianou, N, Nouri, M, McGowan, K, Lehman, M L, McPherson, S J, Roshan-Moniri, M, Butler, M S, Caradec, J, Gregory-Evans, C Y, McGovern, J, Das, R, Takhar, M, Erho, N, Alshalafa, M, Davicioni, E, Schaeffer, E M, Jenkins, R B, Ross, A E, Karnes, R J, Den, R B, Fazli, L, Gregory, P A, Gleave, M E, Williams, E D, Rennie, P S, Buttyan, R, Gunter, J H, Selth, L A, Russell, P J, Nelson, C C, Hollier, B G
Publicado 2017

NLRP1 promotes tumor growth by enhancing inflammasome activation and suppressing apoptosis in metastatic melanoma

por Zhai, Zili, Liu, Weimin, Kaur, Manjinder, Luo, Yuchun, Domenico, Joanne, Samson, Jenny Mae, Shellman, Yiqun G, Norris, David A, Dinarello, Charles A, Spritz, Richard A, Fujita, Mayumi
Publicado 2017

Connexin-43 channels are a pathway for discharging lactate from glycolytic pancreatic ductal adenocarcinoma cells

por Dovmark, T H, Saccomano, M, Hulikova, A, Alves, F, Swietach, P
Publicado 2017