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161por Green, Angharad E, Amézquita, Alejandro, Le Marc, Yvan, Bull, Matthew J, Connor, Thomas R, Mahenthiralingam, Eshwar“…The consistent differential expression of five genetic pathways during exposure to multiple industrial growth conditions associated with benzisothiazolone (BIT) and phenoxyethanol (POE) preservatives, and a laundry detergent (LD) formulation, was observed. A MexPQ-OpmE Resistance Nodulation Division efflux pump system was commonly upregulated in response to POE, a combination of BIT and POE, and LD together with BIT. …”
Publicado 2018
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162por Pravda, Lukáš, Sehnal, David, Toušek, Dominik, Navrátilová, Veronika, Bazgier, Václav, Berka, Karel, Svobodová Vařeková, Radka, Koča, Jaroslav, Otyepka, Michal“…The tool is interconnected with other bioinformatics tools (e.g., PDBe, CSA, ChannelsDB, OPM, UniProt) to help both setup and the analysis of acquired results. …”
Publicado 2018
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163por Raimo, Maria“…Examination by an optical polarizing microscope (OPM) has shown an intermittent high and low birefringence along fibers. …”
Publicado 2020
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164por Bordini, Jessica, Morisi, Federica, Cerruti, Fulvia, Cascio, Paolo, Camaschella, Clara, Ghia, Paolo, Campanella, Alessandro“…Here, we defined the mechanisms of iron toxicity in MM.1S, U266, H929, and OPM-2 MM cell lines, and validated this strategy in preclinical studies using Vk*MYC mice as MM model. …”
Publicado 2020
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165por Sapoznik, Etai, Chang, Bo-Jui, Huh, Jaewon, Ju, Robert J, Azarova, Evgenia V, Pohlkamp, Theresa, Welf, Erik S, Broadbent, David, Carisey, Alexandre F, Stehbens, Samantha J, Lee, Kyung-Min, Marín, Arnaldo, Hanker, Ariella B, Schmidt, Jens C, Arteaga, Carlos L, Yang, Bin, Kobayashi, Yoshihiko, Tata, Purushothama Rao, Kruithoff, Rory, Doubrovinski, Konstantin, Shepherd, Douglas P, Millett-Sikking, Alfred, York, Andrew G, Dean, Kevin M, Fiolka, Reto P“…We present an oblique plane microscope (OPM) that uses a bespoke glass-tipped tertiary objective to improve the resolution, field of view, and usability over previous variants. …”
Publicado 2020
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166por Tierney, Tim M., Levy, Andrew, Barry, Daniel N., Meyer, Sofie S., Shigihara, Yoshihito, Everatt, Matt, Mellor, Stephanie, Lopez, Jose David, Bestmann, Sven, Holmes, Niall, Roberts, Gillian, Hill, Ryan M, Boto, Elena, Leggett, James, Shah, Vishal, Brookes, Matthew J., Bowtell, Richard, Maguire, Eleanor A., Barnes, Gareth R.“…We then constructed a fitted dental mould to accommodate an Optically Pumped Magnetometer (OPM). We collected data using a previously validated hippocampal-dependant task to test the empirical utility of a mouth-based sensor, with an accompanying array of left and right temporal lobe OPMs. …”
Publicado 2021
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167por A. A. Hussein, Mohammed, Eid, Manal, Rahimi, Mehdi, Filimban, Faten Zubair, Abd El-Moneim, Diaa“…The RAPD markers OPA_01, OPM_12 followed by OPO_12 and SSR markers MIAC_4, MIAC_5 followed by mMiCIR_21 were the most informative in terms of describing genetic variability among the cultivars under study; they can be used in further investigations such as genetic mapping or marker-assisted selection. …”
Publicado 2023
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168“…METHODOLOGY: We have exploited the impaired metabolic fitness of a P. aeruginosa mutant strain lacking several efflux pump of the resistance nodulation cell division superfamily and the TolC homolog OpmH, and isolated derivatives (large colony variants) that regained fitness by incubation on nutrient-rich medium in the absence of antibiotics. …”
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169por Strempel, Nikola, Neidig, Anke, Nusser, Michael, Geffers, Robert, Vieillard, Julien, Lesouhaitier, Olivier, Brenner-Weiss, Gerald, Overhage, Joerg“…Microarray analyses of P. aeruginosa cells exposed to LL-37 revealed an upregulation of gene clusters involved in the production of quorum sensing molecules and secreted virulence factors (PQS, phenazine, hydrogen cyanide (HCN), elastase and rhamnolipids) and in lipopolysaccharide (LPS) modification as well as an induction of genes encoding multidrug efflux pumps MexCD-OprJ and MexGHI-OpmD. Accordingly, we detected significantly elevated levels of toxic metabolites and proteases in bacterial supernatants after LL-37 treatment. …”
Publicado 2013
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170“…It has been argued that the emergence of roughly periodic orientation preference maps (OPMs) in the primary visual cortex (V1) of carnivores and primates can be explained by a so-called statistical connectivity model. …”
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171por Chen, Wen-Jen, Kuo, Tzu-Yen, Hsieh, Feng-Chia, Chen, Pi-Yu, Wang, Chang-Sheng, Shih, Yu-Ling, Lai, Ying-Mi, Liu, Je-Ruei, Yang, Yu-Liang, Shih, Ming-Che“…In addition, we also showed that other export systems, i.e., the PvdRT-OpmQ and MexAB-OprM efflux systems (for which there have been previous suggestions of involvement) and the type II secretion system (T2SS), are not involved in pyoverdine secretion.…”
Publicado 2016
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172por Steiner, Normann, Borjan, Bojana, Hajek, Roman, Jöhrer, Karin, Göbel, Georg, Willenbacher, Wolfgang, Kern, Johann, Gunsilius, Eberhard, Untergasser, Gerold“…The human MM cell lines U266, NCI-H929 and OPM-2 were used for functional GRP78 release- and processing studies after induction of acidosis, ER stress, apoptosis and necrosis. …”
Publicado 2017
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173por Dimopoulos, Konstantinos, Søgaard Helbo, Alexandra, Fibiger Munch‐Petersen, Helga, Sjö, Lene, Christensen, Jesper, Sommer Kristensen, Lasse, Asmar, Fazila, Hermansen, Niels Emil Ulrich, O'Connel, Casey, Gimsing, Peter, Liang, Gangning, Grønbæk, Kirsten“…In an effort to comprehend the precise mechanisms behind the development of IMiD resistance and examine whether it is potentially reversible, we established lenalidomide‐resistant (‐LR) and pomalidomide‐resistant (‐PR) human myeloma cell lines from two IMiD‐sensitive cell lines, OPM2 and NCI‐H929, by continuous culture in the presence of lenalidomide or pomalidomide for 4–6 months, until acquirement of stable resistance. …”
Publicado 2017
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174por Pfeiffer, Christoph, Andersen, Lau M., Lundqvist, Daniel, Hämäläinen, Matti, Schneiderman, Justin F., Oostenveld, Robert“…With advances in magnetic field sensing technologies, e.g., high-T(c) SQUIDs and optically pumped magnetometers (OPM), that require less extreme operating temperatures than low-T(c) SQUID sensors, on-scalp MEG is on the horizon. …”
Publicado 2018
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175por Weißbach, Susann, Heredia-Guerrero, Sofia Catalina, Barnsteiner, Stefanie, Großhans, Lukas, Bodem, Jochen, Starz, Hanna, Langer, Christian, Appenzeller, Silke, Knop, Stefan, Steinbrunn, Torsten, Rost, Simone, Einsele, Hermann, Bargou, Ralf Christian, Rosenwald, Andreas, Stühmer, Thorsten, Leich, Ellen“…Specifically, KRAS(WT), KRAS(p.G12A), KRAS(p.A146T), and KRAS(p.A146V) were overexpressed in HEK293 cells and the KRAS(WT) MM cell lines JJN3 and OPM2 using lentiviral transduction and the Sleeping Beauty vector system. …”
Publicado 2020
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176por Handa, Hiroshi, Honma, Kazuki, Oda, Tsukasa, Kobayashi, Nobuhiko, Kuroda, Yuko, Kimura-Masuda, Kei, Watanabe, Saki, Ishihara, Rei, Murakami, Yuki, Masuda, Yuta, Tahara, Ken-ichi, Takei, Hisashi, Kasamatsu, Tetsuhiro, Saitoh, Takayuki, Murakami, Hirokazu“…The MM cell lines KMS11, KMS12PE, OPM2, and RPMI8226 were treated with JQ1, an MYC super-enhancer inhibitor, or MYC inhibitor 10058-F4. …”
Publicado 2020
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177por Mellor, Stephanie, Tierney, Tim M., O’Neill, George C., Alexander, Nicholas, Seymour, Robert A., Holmes, Niall, López, José D., Hill, Ryan M., Boto, Elena, Rea, Molly, Roberts, Gillian, Leggett, James, Bowtell, Richard, Brookes, Matthew J., Maguire, Eleanor A., Walker, Matthew C., Barnes, Gareth R.“…BACKGROUND: Optically pumped magnetometers (OPMs) have made moving, wearable magnetoencephalography (MEG) possible. …”
Publicado 2022
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178por DASH, DEBADATTA, WISLER, ALAN, FERRARI, PAUL, DAVENPORT, ELIZABETH MOODY, MALDJIAN, JOSEPH, WANG, JUN“…Fortunately, recently developed optically pumped magnetometers (OPM) do not require cryogens, and have the potential to be wearable and movable making them more suitable for BCI applications. …”
Publicado 2020
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179“…Moreover, the levels of CTCs and IL-6 in the occult peritoneal metastasis (OPM) group and the CT-positive PM group were higher than those in the negative PM (P<0.05). …”
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180por da Cruz Nizer, Waleska Stephanie, Adams, Madison Elisabeth, Inkovskiy, Vasily, Beaulieu, Carole, Overhage, Joerg“…Among them were 10 mutants with a disrupted nrdJa, bvlR, hcnA, orn, sucC, cysZ, nuoJ, PA4166, opmQ, or thiC gene, which also exhibited a significant growth defect in the presence of NaOCl. …”
Publicado 2023
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