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161“…The present study was designed to clarify the effect of intranasal miR-410 administration in an ovalbumin (OVA)-induced murine model of asthma. It was found that miR-410 expression was significantly decreased in the lungs of OVA-induced asthmatic mice (P<0.05) and miR-410 was overexpressed via intranasal instillation. …”
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162por Lee, Chang Doo, Choi, Won Seok, Choi, Yong Geon, Kang, Hyun Sik, Lee, Wang Tae, Kim, Hong Jo, Lee, Ji-Yun“…METHODS: Allergic lung inflammation was evoked by ovalbumin (OVA) alone or co-exposure with lipopolysaccharide (LPS) in a murine asthma model. …”
Publicado 2020
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163por Pan, Jing, Yang, Qianyuan, Zhou, Yao, Deng, Huan, Zhu, Yifan, Zhao, Deyu, Liu, Feng“…This study aimed to determine whether microRNA-221 (hereafter, miR-221) can affect airway remodeling in a mouse model of ovalbumin (OVA)-induced chronic asthma. METHODS: Adeno-associated viruses (AAVs) “Bearing miR-221 sponges” were used to downregulate miR-221 in asthmatic mice. …”
Publicado 2020
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164“…In this study, we established the mouse asthma model following the ovalbumin (OVA) method in C57BL/6 mice and the cell model with IL-13 induction in bronchial epithelial cells (BEAS-2B cells). …”
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165“…The aqueous extract was found to be more effective on the surfactant system of lung against ova albumin and aluminium hydroxide induced lung damage in albino wistar rats. …”
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166por Mothes, Benedikt, Bucher, Kirsten, Ammon-Treiber, Susanne, Schwab, Matthias, Piekorz, Roland P., Hirsch, Emilio, Nürnberg, Bernd, Beer-Hammer, SandraEnlace del recurso
Publicado 2016
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167por Peng, Shuang, Gao, Jian, Liu, Wen, Jiang, Chunhong, Yang, Xiaoling, Sun, Yang, Guo, Wenjie, Xu, Qiang“…In this study, we attempted to explore the effect and possible mechanism of Andrographolide on OVA-induced asthma. OVA challenge induced significant airway inflammatory cell recruitment and lung histological alterations, which were ameliorated by Andrographolide. …”
Publicado 2016
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169por Gao, Liuchuang, Wu, Min, Liu, Hangyu, He, Miao, Jiang, Han, Shang, Runshi, Wang, Qiangqiang, Song, Zhu, Huang, Yafei, Han, Junyan“…However, the underlying mechanisms remain elusive, especially in ovalbumin (OVA)-induced neonatal allergic asthma model. Here, we used the OVA-induced asthma model in two age groups, neonatal and adult, when mice were first sensitized with peritoneal OVA/alum as neonates and adults, respectively. …”
Publicado 2021
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170por Duan, Cuicui, Ma, Lin, Yu, Jie, Sun, Yixue, Liu, Lifan, Ma, Fumin, Li, Xiaolei, Li, Dan“…Furthermore, OVA-specific immunoglobulin E (IgE), OVA-specific-IgG1, and plasma histamine levels were declined in mice treated with L. plantarum JC7 than in OVA-sensitised mice. …”
Publicado 2022
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171por Jia, Jufang, Zeng, Mengnan, Zhu, Denghui, Jiao, Xinmian, Zhang, Beibei, Yang, Ruolan, Feng, Weisheng, Zheng, Xiaoke“…In this study, we replicated an OVA-sensitized/challenged allergic asthma mouse model, and divided the mice into a model (OVA) group, positive drug (Y, 0.5 mg/kg/day) group, and EB-A treatment with low (Low, 10 mg/kg/day) and high dose (High, 20 mg/kg/day) groups. …”
Publicado 2022
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172por Bouike, Go, Nishitani, Yosuke, Shiomi, Hideyuki, Yoshida, Masaru, Azuma, Takeshi, Hashimoto, Takashi, Kanazawa, Kazuki, Mizuno, Masashi“…To clarify the mechanism of the antiallergic activity of Agaricus blazei Murill extract (ABME), the present paper used an in vivo allergy model and an in vitro intestinal gut model. During OVA sensitization, the serum IgE levels decreased significantly in ABME group. …”
Publicado 2011
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173por Schülke, Stefan, Wolfheimer, Sonja, Gadermaier, Gabriele, Wangorsch, Andrea, Siebeneicher, Susanne, Briza, Peter, Spreitzer, Ingo, Schiller, Dirk, Loeschner, Bettina, Uematsu, Satoshi, Ryffel, Bernard, Akira, Shizuo, Waibler, Zoe, Vieths, Stefan, Toda, Masako, Scheurer, Stephan“…Objective of the present study was to gain further insight into the mechanisms by which flagellin fusion proteins mediate their immune modulating effects. In a mouse model of Ova-induced intestinal allergy a fusion protein of flagellin and Ova (rflaA:Ova) was used for intranasal and intraperitoneal vaccination. …”
Publicado 2014
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174por Dugger, Kari J., Chrisman, Taylor, Sayner, Sarah L., Chastain, Parker, Watson, Kacie, Estes, Robert“…RESULTS: For the allergic asthma model, female wildtype BALB/c mice were challenged with OVA, and exercised (13.5 m/min for 45 min) 3×/week for 4 weeks. …”
Publicado 2018
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175“…METHODS: To investigate the anti-allergenic mechanism of BLAB tea, we treated ovalbumin (OVA)-induced allergic rhinitis (AR) model of mice with BLAB tea, and elucidated its possible mechanism of action. …”
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176“…The objective of this study was to determine whether P. linteus ethanol extract (PLE) suppresses inflammatory response in an OVA-induced asthma model. As expected, the oral administration of PLE significantly inhibited eosinophilic airway inflammation and airway hyperresponsiveness in OVA-challenged BALB/c mice. …”
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177por Hammerschmidt-Kamper, Christiane, Biljes, Daniel, Merches, Katja, Steiner, Irina, Daldrup, Thomas, Bol-Schoenmakers, Marianne, Pieters, Raymond H. H., Esser, CharlotteEnlace del recurso
Publicado 2017
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178por He, Qian, Jiang, Lang, Cao, Kangli, Zhang, Linxia, Xie, Xinci, Zhang, Shuye, Ding, Xiangqing, He, Yongquan, Zhang, Miaomiao, Qiu, Tianyi, Jin, Xuanxuan, Zhao, Chen, Zhang, Xiaoyan, Xu, JianqingEnlace del recurso
Publicado 2020
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179por Zhou, Fang-mei, Chen, Yu-chi, Jin, Chao-ying, Qian, Chao-dong, Zhu, Bing-qi, Zhou, Ying, Ding, Zhi-shan, Wang, Yi-qi“…In vivo results show SYQP enhanced antigen-specific spleen lymphocyte proliferation and serum IgG levels in OVA-immunized C57BL/6 mice. Orally administered 200 mg/kg SYQP induced obvious tumor regression, spleen weight increase, and the upregulation of the mRNA expression of TLR4-related cytokines in Lewis lung carcinoma–bearing mice. …”
Publicado 2021
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180por He, Xiang, Zhang, Lei, Hu, Lingjuan, Liu, Shengbin, Xiong, Anying, Wang, Junyi, Xiong, Ying, Li, Guoping“…RESULTS: In this study, we found PM2.5 aggravated airway inflammation in OVA-induced asthmatic mice. RNA-seq analysis also showed that epithelial mesenchymal transition (EMT) was enhanced in OVA-induced mice exposed to PM2.5 compared with that in OVA-induced mice. …”
Publicado 2021
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