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  1. 2001
    “…It was feasible to perform stereotactic high-precision RT after defining tumor and OARs by CT imaging. After stereotactic RT, a high rate of DNA damage was mainly observed in the tumor but not in OARs. …”
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    Online Artículo Texto
    Histopathological Tumor and Normal Tissue Responses after 3D-Planned Arc Radiotherapy in an Orthotopic Xenograft Mouse Model of Human Pancreatic Cancer
  2. 2002
    por Reitz, Bodo, Miften, Moyed
    Publicado 2008
    “…The plans were optimized to achieve the same clinical objectives concerning dose to the target volume and to the relevant organs‐at‐risk (OARs). The number of intensity levels were minimized until the clinical objectives could not be achieved anymore. …”
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    Comparison of the KonRad IMRT and XiO treatment planning systems
  3. 2003
    “…It includes two integrated indices 1.Integrated Dosimetric Index for tumor (IDI(Tumor)) dose coverage and 2.Integrated Dosimetic Index (IDI(organs)) for Organs At Risk (OARs). PQI was used to select better dosimetric plan form multiple VMAT plans of a Nasopharynx case. …”
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    Online Artículo Texto
    Plan Quality Index – An Integrated Dosimetric Approach for Plan Evaluation with Consideration of Quality of Dose Coverage to Tumors and Quality of Organs’ Sparing
  4. 2004
    “…Meanwhile, the dose to OARs and the coverage of the target are comparable in the two plans. …”
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    Online Artículo Texto
    A planning strategy may reduce the risk of heart diseases and radiation pneumonia: Avoiding the specific heart substructures
  5. 2005
    “…Conclusion Our findings reveal distinct radiation exposure patterns to OARs of nasopharyngeal carcinoma. This research emphasises the need for tailored radiation therapy planning to achieve optimal clinical outcomes while safeguarding vital organs.…”
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    Understanding the Radiation Dose Variability in Nasopharyngeal Cancer: An Organs-at-Risk Approach
  6. 2006
    “…Deformed volumes of targets and organs at risk (OARs) in the CBCT were compared with those in the planning CT. …”
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    CBCT-based volumetric and dosimetric variation evaluation of volumetric modulated arc radiotherapy in the treatment of nasopharyngeal cancer patients
  7. 2007
    “…Our two-phase adaptive IMRT protocol improves dosimetric results in terms of target volumes and OARs in patients with locally advanced NPC.…”
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    A dosimetric comparison of two-phase adaptive intensity-modulated radiotherapy for locally advanced nasopharyngeal cancer
  8. 2008
    “…RA plans were evaluated in terms of planning target volume (PTV) coverage, dose to organs at risk (OARs), conformity index (CI), homogeneity index (HI), gradient measure, external volume index of dose distribution produced, total number of monitor units (MUs), nontumor integral dose (ID), and low dose volume of normal tissue. …”
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    Online Artículo Texto
    The dosimetric impact of different photon beam energy on RapidArc radiotherapy planning for cervix carcinoma
  9. 2009
    “…Dosimetric and radiobiological comparisons for planning target volume (PTV) and organs at risk (OARs) were performed by means of a dose‐volume histogram (DVH), equivalent uniform dose (EUD), and local tumor control probability (LTCP). …”
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    Local tumor control probability to evaluate an applicator‐guided volumetric‐modulated arc therapy solution as alternative of 3D brachytherapy for the treatment of the vaginal vault in patients affected by gynecological cancer
  10. 2010
    “…We concluded that the dose to OARs such as ribs and chest wall could be reduced with improved target conformity using VMAT instead of 3D-CRT for SBRT to treat peripheral lung tumors.…”
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    Possibility of chest wall dose reduction using volumetric-modulated arc therapy (VMAT) in radiation-induced rib fracture cases: comparison with stereotactic body radiation therapy (SBRT)
  11. 2011
    “…Differences in target volumes and dose distributions in OARs and PTVs were then evaluated with various metrics such as the DICE Similarity Coefficient and the homogeneity index. …”
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    Volumetric and dosimetric comparison of two delineation guidelines for the radiation treatment of laryngeal squamous cell carcinoma
  12. 2012
    “…A planning target volume (PTV) and organs at risk (OARs) were recorded with DVH analysis. RESULTS: The study describes the full procedure of breast HDR brachytherapy with the lumpectomy. …”
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    Experience in multicatheter interstitial high-dose-rate breast brachytherapy: dose-volume histogram analysis of the first results
  13. 2013
    “…RESULTS: Tumor coverage and dose to OARs was significantly better with volumetric-modulated arc therapy (VMAT). …”
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    Evaluation of Healthy Tissue Dose at Different Regions between Volumetric-Modulated Arc Therapy and Intensity-Modulated Radiation Therapy Plans in the Treatment of Various Cancers
  14. 2014
    “…The dose deposited in organs at risk (OARs) gradually decreased, and the PQM values gradually improved following each optimization. …”
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    A longitudinal evaluation of improvements in treatment plan quality for lung cancer with volumetric modulated arc therapy
  15. 2015
    por Park, So Hyun, Choi, Jinhyun
    Publicado 2021
    “…CONCLUSION: The application of a radiation bra was associated with better geometric and dosimetric planning parameters, with a smaller CTV and lower doses to the OARs (lungs and heart) in the radiotherapy field. …”
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    Analysis of Geometric and Dosimetric Effects of Bra Application to Support Large or Pendulous Breasts During Radiotherapy Planning: A Retrospective Single-Center Study
  16. 2016
    “…Recently, proton therapy has been evaluated for mediastinal HL treatment, due to its possibility to significantly reduce integral dose to OARs, which is expected to limit second neoplasm risk and reduce late toxicity. …”
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    Current Situation of Proton Therapy for Hodgkin Lymphoma: From Expectations to Evidence
  17. 2017
    “…Modern inverse planning radiotherapy techniques allow for organs at risk (OARs) to evade radiation doses that they would have been subjected to with earlier techniques. …”
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    Development of a CT-Based Auto-Segmentation Model for Prostate-Specific Membrane Antigen (PSMA) Positron Emission Tomography-Delineated Tubarial Glands
  18. 2018
    “…Rectum and bladder were considered reference organs at risk (OARs). Following dose (D) parameters were examined: D(max) (0.5 cc), D(20%) and D(50%) for rectum, D(max) (0.5 cc) and D(50%) for bladder; for each parameter, differences between the two adopted methods were reported as Δ-values. …”
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    Reliability of algebraic sum to evaluate adjuvant pelvic radiotherapy and vaginal cuff brachytherapy cumulative doses in uterine cancers
  19. 2019
    “…MAIN OUTCOMES AND MEASURES: The main outcomes were organs at risk (OARs) dosimetric outcomes, prognosis (overall survival [OS], progression-free survival [PFS], and objective response rate [ORR]), and radiation-related toxic effects. …”
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    Efficacy and Safety in Proton Therapy and Photon Therapy for Patients With Esophageal Cancer: A Meta-Analysis
  20. 2020
    “…However, this could cause underdosage of the treatment volume and overdosage of the organs at risk (OARs). To reduce this problem, in this proof of principle study we developed and evaluated a novel adaptive planning method. …”
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    Real-time adaptive planning method for radiotherapy treatment delivery for prostate cancer patients, based on a library of plans accounting for possible anatomy configuration changes
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