“…In addition to established dysphagia organs-at-risk (OARs), our data suggest that epiglottic and submandibular gland doses are important for swallowing function post-RT. …”
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“…T2-weighted MRI prior and after the treatment session were acquired to contour gross tumor volumes (GTVs) and organs at risk (OARs). The datasets were used to simulate four different boost strategies (all with 15 Gy/5 fractions in addition to 50.4 Gy): up-front boost (5 daily fractions in the first week of treatment) and an adaptive boost (one boost fraction per week). …”
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“…The mean age of these respondents was 73.5 (SD ± 6.39) years. 73.3% (n = 22) were female and 26.1% (n = 8) were male.  63.3% of patients were white, 16.6% were Black, 13.3% were Hispanic, and 6.6% were Asian. 50% of patients were married, 26.6% were divorced, and 23.3% were widowed. 10% of patients were still working, while the remaining 90% were retired.  33.3% of patients had an associate, bachelor's, or graduate/advanced degree, 63.3% of patients completed high school, and 3.3% had not.  73% lived with at least one other person and 27% lived alone.  86.7% had one or more children and 13.3% were childless.  The mean OARS score was 3.16 (SD ± 1.88) (range 0-6, worse to best perceived health).  …”
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“…High-risk nodal regions were simultaneously prescribed: 59.4 Gy in 1.8 Gy fractions, and more than 95% received at least 56.4 Gy. Organs at risk (OARs) were kept below their dose constraints. The patient tolerated both the procedures with no grade ≥ 2 treatment-related adverse events. …”
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“…Elements abstracted from each manuscript included the study outcome, organs-at-risk (OARs) considered, DVH parameters analyzed, summary of the analytic approach, use of multivariable statistics, goodness-of-fit reporting, completeness of model reporting, assessment of multicollinearity, adjustment for multiple comparisons, and methods for dichotomizing variables. …”
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“…For each fraction, the differences respect to the treatment plan values of OARs and PTV dosimetric parameters were analyzed: ΔD(mean), ΔD95%, ΔD98%, ΔD2%, ΔV36Gy, ΔV38.5Gy, and ΔV43.5Gy. …”
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“…Accurate gating of target volumes, the online adaptive planning workflow and the high definition of MRI treatment images allow delivering high doses to the PTV while efficiently sparing organs at risk (OARs).…”
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“…Dosimetric data, including isodose lines, HR-CTV (D(100), V(150%), V(200%), HI, and CI), and (bladder, rectum, and intestines) D(1cc), D(2cc) for organs at risk (OARs) were also collected. Additionally, TCP, NTCP, BED, and EUBED were calculated, and differences were analyzed using matched samples t-test and Friedman test. …”
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“…The conformity index (CI), homogeneity index (HI), radiation dose of organs at risk (OARs), and oral mucosal reaction were compared among the three groups. …”
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“…Radiation dose to target volumes (D(90) of high-risk clinical target volume) and organs at risk (OARs) (D(0.1cc), D(1cc), and D(2cc) of bladder, rectum, and sigmoid) were calculated for each virtual applicator shift, and significance of displacements was assessed using general linear model and Kruskal-Wallis test. …”
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“…CONCLUSIONS: Comparing to the sMLC, the mMLC not only demonstrated higher efficiencies and more optimal target coverage, but also considerably improved the dose sparing of OARs in the IMRT planning for UTEC.…”
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“…The dose-volume constraints for organs at risk (OARs) were observed in 19 patients using a single-arc technique. …”
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“…This study sought to compare the differences in target volumes and dose distributions to the targets and organs at risk (OARs) between a four-dimensional computed tomography (4DCT)-based respiratory-gated intensity-modulated radiation therapy (IMRT) plan (Plan(EOE)) and a three-dimensional CT (3DCT)-based IMRT plan (Plan(3D)) in patients with non-small-cell lung cancer (NSCLC). …”
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“…An optimal choice of these factors is fundamental to obtain the desired target coverage with the lowest achievable dose to the organs at risk (OARs). This study evaluates relevant dose parameters in cervix brachytherapy in order to assess existing tandem-ring dwell time ratio used at the first HDR BT center in Nigeria, and compare it with an alternative source loading pattern. …”
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“…Dose‐volume histograms and equivalent uniform doses (EUD) for planning target volumes (PTVs) and organs at risk (OARs) were generated. The four techniques resulted in comparable mean, minimum, maximum PTV doses, and PTV EUDs ([Formula: see text]). …”
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“…DVHs and derived metrics, such as the homogeneity index (HI), the doses to [Formula: see text] and [Formula: see text] volumes, and mean dose [Formula: see text] of the whole brain (i.e., PTV), and the organs at risk (OARs) such as lens and skull, were obtained. The PPW plans from both Eclipse and XiO systems uncovered the following advantages: (1) encompassing a cribriform plate area with the 100% isodose line was better than either PPWO or XP, according to calculated two‐dimensional distributions of one patient; (2) the mean value of [Formula: see text] for lens was reduced to 23.6% of [Formula: see text] from 54.1% for PPWO or 41.6% for XP; and (3) the mean value of [Formula: see text] for skull was reduced to 94.8% of [Formula: see text] from either 98.4% for PPWO or 98.3% for XP. …”
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“…Target coverage (TC), homogeneity index (HI), conformity index (CI), maximum dose (Dmax), minimum dose (Dmin) and dose to organs at risk (OARs) were compared. RESULTS: All plans met the indicated dose restrictions. …”
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“…CONCLUSIONS: A high dose rate brachytherapy fractionation schedule of 6.5 Gy × 4 fractions over 2 days for CTV(HR) is associated with reduced overall treatment time, a slightly higher local control rate and lesser dose to OARs compared to 9 Gy × 2 fractions given one week apart to point A.…”
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“…Dosage differences in target regions and organs at risk (OARs) were analyzed between both the plans. Four planes were selected in the longitudinal direction of uterine cervix and divided the 360° area around the tandem into eight equal sectors. …”
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