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441por Bainbridge, Hannah E., Menten, Martin J., Fast, Martin F., Nill, Simeon, Oelfke, Uwe, McDonald, Fiona“…Using reduced margins alleviated this issue and decreased exposure of several other organs-at-risk (OAR). Reduced margins also enabled increased isotoxic target dose escalation. …”
Publicado 2017
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442“…Small lateral offsets of the flattening filter caused significant variation to the OAR. In general, the greatest sensitivity to accelerator parameters could be observed for higher energies and off‐axis ratios closer to the central axis. …”
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443por Hansen, Christian Rønn, Bertelsen, Anders, Hazell, Irene, Zukauskaite, Ruta, Gyldenkerne, Niels, Johansen, Jørgen, Eriksen, Jesper G., Brink, Carsten“…Target doses were more homogenous with the AU plans and the OAR doses were significantly reduced, between 0.5 and 6.5 Gy. …”
Publicado 2016
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444por Gómez-Santos, Nuria, Glatter, Timo, Koebnik, Ralf, Świątek-Połatyńska, Magdalena Anna, Søgaard-Andersen, Lotte“…Here, we show that the TBDT Oar in Myxococcus xanthus is required for secretion of a protein, protease PopC, to the extracellular milieu. …”
Publicado 2019
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445por Davis, Anne T, Muscat, Sarah, Palmer, Antony L., Buckle, David, Earley, James, Williams, Matthew G.J., Nisbet, Andrew“…When within ±20 HU for soft tissue and ±50 HU for bone and air the dose change in the PTV and OAR was within ±0.5% and ±1% respectively. CONCLUSIONS: : When imaging parameters were changed, if HU change was within ±20 HU for soft tissue and ±50 HU for bone and air, the change in the PTV and OAR doses was below 1%. …”
Publicado 2019
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446“…The cold spots ratio of PTV and hot spots ratio of OAR were able to be evaluated by the modified scheme. …”
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447por Wortel, Geert, Eekhout, Dave, Lamers, Emmy, van der Bel, René, Kiers, Karen, Wiersma, Terry, Janssen, Tomas, Damen, Eugène“…Starting from a simple automation protocol which consisted of the constraints for targets and organs at risk (OAR), the performance of the automatic approach was evaluated in terms of target coverage, OAR sparing, conformity, beam complexity, and plan quality. …”
Publicado 2021
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448por Temme, Nils, Hermann, Robert Michael, Hinsche, Tanja, Becker, Jan-Niklas, Sonnhoff, Mathias, Kaltenborn, Alexander, Carl, Ulrich Martin, Christiansen, Hans, Geworski, Lilli, Nitsche, Mirko“…In the EBRT of “B + PSR”, supine positioning significantly reduced the OAR “heart” exposure but increased the dose to the OARs “ipsilateral lung” and “lymphatic regions”. …”
Publicado 2022
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449“…RESULTS: This study indicated that IMRT can treat cervical cancer more efficiently with less damage to OARs as compare to 3DCRT. CONCLUSION: In this study, we observe that the IMRT plans with subtracting rectal volume achieve better OAR sparing.…”
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450por Smirnova, Anastasia O, Miroshnichenkova, Anna M, Olshanskaya, Yulia V, Maschan, Michael A, Lebedev, Yuri B, Chudakov, Dmitriy M, Mamedov, Ilgar Z, Komkov, Alexander“…Calculating this anomaly, we formulated a quantitative measure of V- and J-genes frequency bias driven by multiplex PCR during library preparation called Over Amplification Rate (OAR). Based on the OAR concept, we developed an original software for multiplex PCR-specific bias evaluation and correction named iROAR: immune Repertoire Over Amplification Removal (https://github.com/smiranast/iROAR). …”
Publicado 2023
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451por Montalvo, Steven K., Kim, Nathan, Nwachukwu, Chika, Alluri, Prasanna, Parsons, David, Lin, Mu‐Han, Cai, Bin, Zhuang, Tingliang, Hrycushko, Brian, Chen, Liyuan, Timmerman, Robert, Rahimi, Asal“…There was no difference in OAR coverage. Average adaptive treatment planning took 15 min and average time‐on‐couch was 34.4 min. …”
Publicado 2022
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452“…Normal lung dose increased as a function of tumor distance from isocenter. For the other OAR, up to 1%–16% reduction of non‐target doses were observed with JT‐VMAT. …”
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453“…Case-based study revealed that CK and PBT plans allowed for excellent sparing of OAR, with some clinical scenarios associated with better performance of CK while others with better performance of PBT. …”
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454por Mazzarotto, Renzo, Simoni, Nicola, Guariglia, Stefania, Rossi, Gabriella, Micera, Renato, De Robertis, Riccardo, Pierelli, Alessio, Zivelonghi, Emanuele, Malleo, Giuseppe, Paiella, Salvatore, Salvia, Roberto, Cavedon, Carlo, Milella, Michele, Bassi, Claudio“…Well-established and accepted OAR dose constraints were used (D(0.5cc) < 33 Gy for luminal OARs and D(0.5cc) < 38 Gy for corresponding PRV(oars)). …”
Publicado 2020
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455por van Marlen, Patricia, Dahele, Max, Folkerts, Michael, Abel, Eric, Slotman, Ben J., Verbakel, Wilko“…Average TB-plan organs-at-risk (OAR) sparing was comparable to IMPT: mean oral cavity/body dose were 4.1/2.5 Gy higher (9.3/2.0 Gy lower than VMAT); most other OAR mean doses differed by <2 Gy. …”
Publicado 2021
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456“…There was no clinically significant difference in dose to LNs, CI, D2cm and maximal doses to OAR between single‐isocenter Halcyon and Truebeam VMAT‐SBRT plans, although, Halcyon plans provided preferably lower maximal dose to adjacent OAR. …”
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457por Wei, Shouyi, Lin, Haibo, Choi, J. Isabelle, Press, Robert H., Lazarev, Stanislav, Kabarriti, Rafi, Hajj, Carla, Hasan, Shaakir, Chhabra, Arpit M., Simone, Charles B., Kang, Minglei“…Single-energy transmission proton PBS plans of 4.5 Gy × 15 fractions were optimized for seven consecutive hepatocellular carcinoma patients, using 2 and 5 fields combined with 1) the minimum MU/spot chosen between 100 and 400, and minimum spot time (MST) of 2 ms, and 2) the minimum MU/spot of 100, and MST of 0.5 ms, based upon considerations in target uniformities, OAR dose constraints, and OAR FLASH dose rate coverage. …”
Publicado 2022
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458por Zimmermann, Marcus, Richter, Anne, Weick, Stefan, Exner, Florian, Mantel, Frederick, Diefenhardt, Markus, Fokas, Emmanouil, Kosmala, Rebekka, Flentje, Michael, Polat, Bülent“…Dose and volume sparing for all OAR could be achieved through VMAT planning and might result in less acute toxicities.…”
Publicado 2022
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459por Laughlin, Brady S., Lo, Stephanie, Vargas, Carlos E., DeWees, Todd A., Van der Walt, Charles, Tinnon, Katie, Beckett, Mason, Hobbis, Dean, Schild, Steven E., Wong, William W., Keole, Sameer R., Rwigema, Jean-Claude M., Yu, Nathan Y., Clouser, Edward, Rong, Yi“…SIMPLE SUMMARY: Organs at risk (OARs) management (rectum and bladder) is evaluated in patients receiving post-prostatectomy radiation. …”
Publicado 2022
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460por Paronetto, Chiara, den Toom, Wilhelm, Milder, Maaike T. W., van Norden, Yvette, Baak, Rogier, Heijmen, Ben J. M., Méndez Romero, Alejandra“…Although target coverages had been planned below desired values in order to protect OARs, many pre-rCTs contained OAR constraint violations: 44.4% for the 6 major constraints. …”
Publicado 2023
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