“…In radiotherapy, computed tomography (CT) datasets are mostly used for radiation treatment planning to achieve a high-conformal tumor coverage while optimally sparing healthy tissue surrounding the tumor, referred to as organs-at-risk (OARs). Based on CT scan and/or magnetic resonance images, OARs have to be manually delineated by clinicians, which is one of the most time-consuming tasks in the clinical workflow. …”
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“…Studied organs were prostate and seminal vesicles, denoted as targets, and bladder, rectum, and urethra, denoted as organs at risk (OARs), which were delineated on MRI scans with a 3.3 mm slice thickness. …”
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“…The DVH is then used to evaluate the volume changes of organs at risk (OAR), the actual dose received by OARs, CTV and PTV during a single fraction. …”
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“…PURPOSE: Radiation therapy (RT) improves control of Hodgkin lymphoma (HL), but patients who undergo RT are at risk for late effects, including cardiovascular disease and second cancers, because of radiation doses to organs at risk (OARs). Proton therapy (PT) can reduce OAR doses compared with conventional photon RT. …”
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“…Violations were often caused by insufficient PTV coverage or, for the multiple lymph node case, a too high dose to OAR in the vicinity of the PTV. With full online replanning it was possible to create plans that met all clinical dose constraints for all cases. …”
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“…The enhancement of the mean dose in OARs distal to the CTV was negligible for the cases investigated. …”
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“…Severe late toxicities and its association with demographic and clinical parameters and dose to OAR were studied. Data was analysed using EpiData analysis v2.2.2.182. …”
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“…CONCLUSION: The study suggests that ICRU 38 point doses are not the true representation of maximum doses to OARs. CT-based treatment planning is more a reliable tool for OAR dose assessment than the conventional 2D radiograph-based plan.…”
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“…AIMS: To compare the contouring of organs at risk (OAR) between a clinical specialist radiation therapist (CSRT) and radiation oncologists (ROs) with different levels of expertise (senior–SRO, junior–JRO, fellow–FRO). …”
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“…MATERIALS AND METHODS: Seventeen annonymized planning CT data sets were used to generate plans for both VMAT and IMRT techniques using 2.5 mm and 5.0 mm MLC.The prescription to the nodule was 45Gy in 5 fractions and to the prostate was 35Gy in 5 fractions.CI, GI, D(2%), D(98%), D(50%) and V(95%) for target; D(2%), Dmean, V(80%), V(20%) for OAR’s; V(5%) of the irradiated volume, and delivered MU’s were analyzed.An independent t-test was used to compare the plans. …”
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“…RESULTS: We observed 3.7%–5.2% change in the plan maximum dose for one cm change in path length to isocenter with increased planning target volume dose, D95 by 4%. The organs at risk (OAR) doses increased as high as 6.8%. Using MU correction method, target volume and OARs dose changes were reduced to <1% when compared with the original plan. …”
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“…The 2.5DJ group had the best ranking for OAR-dose, followed by the 2.5FJ and 5.0DJ groups with a same score. …”
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“…For patients with critical OARs abutting target volumes on their reference image we have demonstrated the potential for a target dose coverage improvement for MRgART compared to C-arm linac treatment.…”
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“…PURPOSE: Segmentation of organs‐at‐risk (OARs) is an essential component of the radiation oncology workflow. …”
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“…Using SC plans provided acceptable dosimetric tolerances for both the target and OARs. However, OAR doses may be increased or decreased based on the constrained marker location and number of trackable markers. …”
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“…The dosimetric parameters for targets and organs at risk (OARs), the normal tissue complication probability (NTCP), the second cancer complication probability (SCCP) for OARs, and the treatment efficiency were assessed and compared. …”
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“…Polymorphic information content (PIC) values, ranging from 0.71 (ETH10) to 0.91 (OarFCB304), were highly polymorphic (PIC  [Formula: see text]  0.5) and informative in studied populations. …”
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“…RESULTS: Gross tumor volume (GTV) and organ at risk (OAR) volumes in the first 13 fractions had no significant changes from the pretreatment planning CT. …”
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“…P < .05) and good sparing of OARs. Nevertheless, the beam-on time showed a significant difference (37 ± 9 m CK; 7.1 ± 0.3 m VMAT; 17 ± 2 m HT. …”
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