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461por Hass, Daniel T., Zhang, Qitao, Autterson, Gillian A., Bryan, Richard A., Hurley, James B., Miller, Jason M. L.“…RESULTS: Medium volumes commonly employed during RPE culture limit diffusion of O(2) to cells, triggering hypoxia, activating HIF-1α, limiting OCR, and dramatically altering cell metabolism, with only minor effects on typical markers of RPE health. …”
Publicado 2023
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462por Varum, Sandra, Rodrigues, Ana S., Moura, Michelle B., Momcilovic, Olga, Easley, Charles A., Ramalho-Santos, João, Van Houten, Bennett, Schatten, Gerald“…ATP levels, lactate production and OCR revealed that human pluripotent cells rely mostly on glycolysis to meet their energy demands. …”
Publicado 2011
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463por Dier, Usawadee, Shin, Dong-Hui, Hemachandra, L. P. Madhubhani P., Uusitalo, Larissa M., Hempel, Nadine“…Bioenergetic profiling also identified a non-OCCC cell line, OVCA420, to have severely compromised mitochondrial function, based on low OCR and a lack of stimulation of maximal respiration following application of the uncoupler FCCP. …”
Publicado 2014
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464por LU, YAO, LI, SU, WU, HENGFANG, BIAN, ZHIPING, XU, JINDAN, GU, CHUNRONG, CHEN, XIANGJIAN, YANG, DI“…The administration of As-IV significantly increased the mitochondrial OCRs, ATP production and the mtDNA levels, and reversed the mitochondrial morphological changes which occurred in the VSMCs. …”
Publicado 2015
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465por Akino, Yuichi, Mizuno, Hirokazu, Isono, Masaru, Tanaka, Yoshihiro, Masai, Norihisa, Yamamoto, Toshijiro“…The maximum variations of the penumbra width for OCR with 10 × 10 mm(2) field size were 0.97 mm. …”
Publicado 2019
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466por Wu, Pingping, Ding, Bin, Ye, Li, Huang, Yanfen, Ji, Jinjun, Fan, Yongsheng, Xu, Li“…Compared to the control cells, the ATP content, OCR, and SOD activity in the ZBDHD-treated cells were significantly higher. …”
Publicado 2020
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467por Alwarawrah, Yazan, Nichols, Amanda G., Green, William D., Eisner, William, Kiernan, Kaitlin, Warren, Jonathan, Hale, Laura P., Beck, Melinda A., MacIver, Nancie J.“…Treatment of isolated CD4(+) T cells with metformin was found to inhibit OCR in vitro and alter the expression of several activation markers. …”
Publicado 2020
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468por Benej, Martin, Wu, Jinghai, Kreamer, McKenzie, Kery, Martin, Corrales-Guerrero, Sergio, Papandreou, Ioanna, Williams, Terence M., Li, Zihai, Graves, Edward E., Selmic, Laura E., Denko, Nicholas C.“…Results: We showed that the pharmacological suppression of mitochondrial oxygen consumption (OCR) in tumor-bearing mice increases tumor oxygenation, while the stimulation of mitochondrial OCR decreases tumor oxygenation. …”
Publicado 2021
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469“…To investigate the impact of diabetes on the cellular metabolism of CMECs, we assessed glycolysis by quantifying the extracellular acidification rate (ECAR), and mitochondrial oxidative phosphorylation (OXPHOS) by measuring cellular oxygen consumption rate (OCR), in isolated CMECs from wild-type (WT) hearts and diabetic hearts (db/db) using an extracellular flux analyzer. …”
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470por Winkelmann, Paula, Unterweger, Anna‐Lena, Khullar, Diya, Beigel, Florian, Koletzko, Leandra, Siebeck, Matthias, Gropp, Roswitha“…In contrast to non‐IBD donors, OCR correlated with ECAR (IBD: cor = 0.79, p = 2E‐10; non‐IBD: cor = 0.37, p = n.s.), in IBD patients. …”
Publicado 2021
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471por Zhang, Kun, Zhang, Tao, Yang, Yuhan, Tu, Wenling, Huang, Hongbin, Wang, Yujun, Chen, Yuzhuo, Pan, Kejian, Chen, Zhuojia“…Methods: The metabolic profiles including ATP generation, glucose consumption, lactate generation, and oxygen consumption rate (OCR) in 5-FU resistant CRC cells were compared with those in their parental cells. …”
Publicado 2022
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472“…Hearing restoration can be achieved with OCR or BAHA.…”
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473“…Glucose also did not alter OCR in sub-confluent cells, in cells exposed to low serum, or in cells treated with added pyruvate. …”
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474por de Mey, Sven, Jiang, Heng, Corbet, Cyril, Wang, Hui, Dufait, Inès, Law, Kalun, Bastien, Estelle, Verovski, Valeri, Gevaert, Thierry, Feron, Olivier, De Ridder, Mark“…Results: Metformin and phenformin inhibited mitochondrial complex I activity and subsequently reduced OCR in a dose-dependent manner starting at 3 mM and 30 μM, respectively. …”
Publicado 2018
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475por van der Stel, Wanda, Carta, Giada, Eakins, Julie, Darici, Salihanur, Delp, Johannes, Forsby, Anna, Bennekou, Susanne Hougaard, Gardner, Iain, Leist, Marcel, Danen, Erik H. J., Walker, Paul, van de Water, Bob, Jennings, Paul“…A battery of tests was utilised, including viability assays, lactate production, mitochondrial membrane potential (MMP) and the Seahorse bioanalyser, which simultaneously measures extracellular acidification rate [ECAR] and oxygen consumption rate [OCR]. CI inhibitors caused a potent decrease in OCR, decreased mitochondrial membrane potential, increased ECAR and increased lactate production in both cell types. …”
Publicado 2020
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476por Li, Xueping, Shen, Huaishuang, Zhang, Mao, Teissier, Victoria, Huang, Ejun Elijah, Gao, Qi, Tsubosaka, Masanori, Toya, Masakazu, Kushioka, Junichi, Maduka, Chima V., Contag, Christopher H., Chow, Simon Kwoon-Ho, Zhang, Ning, Goodman, Stuart B.“…To understand the oxygen consumption rate (OCR), we used Seahorse XF Cell Mito Stress Test Kit with Seahorse XF96 analyzer. …”
Publicado 2023
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477“…In the LabVIEW programming environment, the edge detection method is used to realize the vehicle target detection, the pattern matching method is used to realize the vehicle logo recognition, and the Optical Character Recognition (OCR) character recognition algorithm is used to realize the vehicle license plate recognition. …”
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478por Wen, Aonan, Zhu, Yujia, Xiao, Ning, Gao, Zixiang, Zhang, Yun, Wang, Yong, Wang, Shengjin, Zhao, Yijiao“…There is no significant difference in the automatic landmark localization accuracy between the TH-OCR algorithm and the MeshMonk algorithm, and both can meet the needs of oral clinical applications to a certain extent.…”
Publicado 2023
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479por Han, Seoyoung, Mueller, Christian, Wuebbolt, Caitlin, Kilcullen, Sean, Nayyar, Varinda, Gonzalez, Brayan Calle, Fard, Ali Mahdavi, Floss, Jamie C., Morales, Michael J., Patel, Sangita P.“…There were no significant changes in HCEnC density, viability, ROS levels, oxidative DNA damage, OCR, and ECAR in response to E2 under either O(2) condition. …”
Publicado 2023
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480por Shen, Han, Chang, Cecilia, Ing, Prunella, Nguyen, Sandy, Mudassar, Faiqa, Cook, Kristina, Lai, Joey, Gloss, Brian, O’Neill, Geraldine, Gee, Harriet, Hau, Eric“…Biguanides are hypoglycemic agents that can reduce the oxygen consumption rate (OCR) in mitochondria, thereby sparing more oxygen and alleviating hypoxia. …”
Publicado 2023
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