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Mostrando 721 - 740 Resultados de 941 Para Buscar '"Ocre"', tiempo de consulta: 0.19s Limitar resultados
  1. 721
    “…Mitochondrial function was analyzed by an electron microscopy scan of cellular structure, mitochondrial DNA copy number, and cellular oxygen consumption rate (OCR). Furthermore, we explored the pathway by which Klotho may function to regulate the antioxidant system. …”
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    Recombinant Klotho Protects Human Periodontal Ligament Stem Cells by Regulating Mitochondrial Function and the Antioxidant System during H(2)O(2)-Induced Oxidative Stress
  2. 722
    “…Mechanistically, by targeting SIX1, miR-489-3p dampens glycolysis, with decreased glucose uptake, lactate production, ATP generation, and extracellular acidification rate (ECAR), as well as an increased oxygen consumption rate (OCR). Importantly, glycolysis regulated by the miR-489-3p/SIX1 axis is critical for its regulation of melanoma growth and metastasis both in vitro and in vivo. …”
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    miR-489-3p/SIX1 Axis Regulates Melanoma Proliferation and Glycolytic Potential
  3. 723
    “…Oxygen consumption rate (OCR), a proxy for mitochondrial function, showed a significant increase in oxidative phosphorylation during the maturation stage, promoting ATP production. …”
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    Mitochondrial Function in Enamel Development
  4. 724
    por Bassan, Sharon
    Publicado 2020
    “…In March, the Office for Civil Rights (OCR) at the U.S. Department for Health and Human Services (HHS) issued a notice titled Notification of Enforcement Discretion for Telehealth Remote Communications During the COVID-19 Nationwide Public Health Emergency (the ‘Notification’). …”
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    Data privacy considerations for telehealth consumers amid COVID-19
  5. 725
    “…Real-time PCR, western blots, OCR, ECAR, lactate production and glucose uptake assays were applied to determine the effect of SLC2A3 on glycolysis reprogramming. …”
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    SLC2A3 promotes macrophage infiltration by glycolysis reprogramming in gastric cancer
  6. 726
    “…In this study, we examined the expression of miR-21, peroxisome proliferator-activated receptor(PPARα), hypoxia-inducible factor(HIF-1α) in the kidney of 3-month-old rats fed ad libitum (YAL), 24-month-old rats fed ad libitum (OAL) and 24-month-old rats subjected to a 70% calorie-restricted diet for 8 months (OCR). We found long-term caloric restriction (CR) ameliorated aging and aging-related fibrosis. …”
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    Caloric restriction alleviates aging-related fibrosis of kidney through downregulation of miR-21 in extracellular vesicles
  7. 727
    “…METHODS: The oxygen consumption rate (OCR) and extracellular acidification rate (ECAR) of cells were examined with a Seahorse XF Extracellular Flux Analyzer. …”
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    TRIB3 Promotes Lung Adenocarcinoma Progression via an Enhanced Warburg Effect
  8. 728
    “…Only consuming the rhizomes (OCR) of the underground parts could significantly reduce the exposure risk of THg and to some extent of MeHg. …”
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    Mercury accumulation in vegetable Houttuynia cordata Thunb. from two different geological areas in southwest China and implications for human consumption
  9. 729
    “…We assessed changes in ventilatory [minute ventilation (V(E)), respiratory frequency (f(R)), and tidal volume (V(T))], hematological (hematocrit and hemoglobin concentration), and metabolic [whole-body O(2) consumption (VO(2)) and CO(2) production (VCO(2)), and liver mitochondrial oxygen consumption rate (OCR) parameters]. Compared to rats, results in mice show increased ventilatory, metabolic, and mitochondrial response. …”
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    Mice and Rats Display Different Ventilatory, Hematological, and Metabolic Features of Acclimatization to Hypoxia
  10. 730
    “…Thus, an increase in both oxygen consumption rates (OCR) and extracellular acidification rates (ECAR) were found in E. bovis–infected host cells indicating a shift from quiescent to energetic cell status. …”
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    Eimeria bovis Macromeront Formation Induces Glycolytic Responses and Mitochondrial Changes in Primary Host Endothelial Cells
  11. 731
    “…Based on the GO enrichment of miR-652-5p target genes, we uncovered that impaired miR-652-5p decreased glycolysis, including reduced the lactate, pyruvate, ATP level and the total extracellular acidification rate (ECAR), elevated oxygen consumption rate (OCR) in T-ALL cell lines. Mechanically, miR-652-5p targeted the 3ʹUTR of Tigar mRNA and inhibited its expression. …”
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    MiR-652-5p elevated glycolysis level by targeting TIGAR in T-cell acute lymphoblastic leukemia
  12. 732
    “…The metabolism change in HDAC2 knockdown GBM cells measures by glucose uptake, lactate production, and OCR/ECAR analysis, indicating that HDAC2 knockdown induces GBM cell death by inhibiting GLUT3. …”
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    miR-3189-targeted GLUT3 repression by HDAC2 knockdown inhibits glioblastoma tumorigenesis through regulating glucose metabolism and proliferation
  13. 733
    “…This decrease correlates with an increase in mitophagy proteins, PINK1, Parkin, and DJ1; an increase in the expression of tumor suppressor PTEN; changes in the expression of mitochondrial biomarkers; and decreases in the oxygen consumption rate (OCR) and tricarboxylic acid enzyme activity. Our bioinformatics analysis suggested that the BMI1 multifunctionality is determined by its high level of intrinsic disorder that defines the ability of this protein to bind to numerous cellular partners. …”
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    BMI1 Silencing Induces Mitochondrial Dysfunction in Lung Epithelial Cells Exposed to Hyperoxia
  14. 734
    “…We performed mitochondrial characterization and assessed oxygen consumption- and extracellular acidification-rates (OCR and ECAR) in addition to oxygen-sensitive respiration and mitochondrial complex activities, using both the Seahorse and Oroboros systems. …”
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    Diversity of respiratory parameters and metabolic adaptation to low oxygen tension in mesenchymal stromal cells
  15. 735
    “…Moreover, inhibition of GLS and GS and levels of oxygen differentially influenced oxygen consumption rate (OCR) and extracellular acidification rate (ECAR). …”
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    Endogenous glutamine is rate-limiting for anti-CD3 and anti-CD28 induced CD4(+) T-cell proliferation and glycolytic activity under hypoxia and normoxia
  16. 736
    “…Cana (100 µM) decreased the oxygen consumption rate (OCR) by 60%, while dapa decreased it by 7%, and ertu and empa (all 100 µM) had no significant effect. …”
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    Differential In Vitro Effects of SGLT2 Inhibitors on Mitochondrial Oxidative Phosphorylation, Glucose Uptake and Cell Metabolism
  17. 737
    “…LPD treatment significantly increased OCR, ATP production, maximal respiration, spare respiratory capacity, and basal respiration in APP/PS1 cells. …”
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    Increasing brain glucose metabolism by ligustrazine piperazine ameliorates cognitive deficits through PPARγ-dependent enhancement of mitophagy in APP/PS1 mice
  18. 738
    “…Then, we evaluated ECAR and OCR levels using a biological energy analyzer to investigate the energy status of colorectal cancer, and the transcriptional regulation was detected by dual luciferase reporter assay and ChIP assay. …”
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    Tadalafil increases the antitumor activity of 5-FU through inhibiting PRMT5-mediated glycolysis and cell proliferation in colorectal cancer
  19. 739
    “…There was a systematic offset of 2.6° in saccade directions, likely reflecting ocular counter roll (OCR; t((13)) = 3.13, p = 0.008). When participants viewed an Earth upright natural scene during head tilt, we found that the orientation of the head still influenced saccade directions (t((13)) = 3.7, p = 0.001). …”
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    Head Orientation Influences Saccade Directions during Free Viewing
  20. 740
    “…A concomitant reduction in mitochondrial respiration was also observed as indicated by a partial loss of oxygen consumption rates (OCR) in isolated mitochondrial fractions of SARS-CoV-2-infected hamster lungs. …”
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    HIF-1α-Dependent Metabolic Reprogramming, Oxidative Stress, and Bioenergetic Dysfunction in SARS-CoV-2-Infected Hamsters
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