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801por Sun, Kexin, Tang, Shifu, Hou, Yixuan, Xi, Lei, Chen, Yanlin, Yin, Jiali, Peng, Meixi, Zhao, Maojia, Cui, Xiaojiang, Liu, Manran“…The increased glycolytic ability of CAFs was validated by measurements of OCR and ECAR and detections of glucose consumption and lactate production. …”
Publicado 2019
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802“…The oxygen consumption rate (OCR) was measured on human islets. In vivo, islets were harvested from C57BL/6 donor mice treated with saline or human AAT and transplanted into the livers of syngeneic mice that had been rendered diabetic by streptozotocin (STZ). …”
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803por Upadhyay, Kapil K., Jadeja, Ravirajsinh N., Vyas, Hitarthi S., Pandya, Bhaumik, Joshi, Apeksha, Vohra, Aliasgar, Thounaojam, Menaka C., Martin, Pamela M., Bartoli, Manuela, Devkar, Ranjitsinh V.“…CORM-A1 treatment improved cellular status by lowering glycolytic respiration and maximizing OCR. Improvement in mitochondrial respiration and increment in ATP production in PA + CORM-A1 treated cells further corroborate our findings. …”
Publicado 2019
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804por Elesela, Srikanth, Morris, Susan B., Narayanan, Samanthi, Kumar, Surinder, Lombard, David B., Lukacs, Nicholas W.“…Furthermore, the oxygen consumption rate (OCR) was reduced as assessed in Seahorse assays, coupled with lower levels of ATP in SIRT1-/- DC. …”
Publicado 2020
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805por Kim, Myoung Sook, Gernapudi, Ramkishore, Cedeño, Yessenia Cedeño, Polster, Brian M., Martinez, Ramon, Shapiro, Paul, Kesari, Santosh, Nurmemmedov, Elmar, Passaniti, Antonino“…In the current study, we show that CADD522 inhibits mitochondrial oxidative phosphorylation by decreasing the mitochondrial oxygen consumption rate (OCR) and ATP production in human breast cancer cells in a RUNX2-independent manner. …”
Publicado 2020
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806por Booij, Johan W., Kuijpers‐Jagtman, Anne Marie, Bronkhorst, Ewald M., Livas, Christos, Ren, Yijin, Kuijpers, Mette A.R., Katsaros, ChristosEnlace del recurso
Publicado 2020
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807“…METTL3 coordinated with YTHDF2 to suppress the expression of PGC-1α, as well as that of cytochrome c (CYCS) and NADH:ubiquinone oxidoreductase subunit C2 (NDUFC2) and reduced ATP production and oxygen consumption rate (OCR). This subsequently increased the accumulation of cellular and mitochondrial reactive oxygen species (ROS) and the levels of proinflammatory cytokines in inflammatory monocytes. …”
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808por Tsakiridis, Evangelia E., Broadfield, Lindsay, Marcinko, Katarina, Biziotis, Olga-Demetra, Ali, Amr, Mekhaeil, Bassem, Ahmadi, Elham, Singh, Kanwaldeep, Mesci, Aruz, Zacharidis, Panayiotis G., Anagnostopoulos, Alexander E., Berg, Tobias, Muti, Paola, Steinberg, Gregory R., Tsakiridis, Theodoros“…This was associated with suppression of oxygen consumption rate (OCR), activation of AMPK, suppression of acetyl-CoA carboxylase (ACC)-DNL and mTOR-p70(s6k)/4EBP1 and HIF1α pathways. …”
Publicado 2021
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809por Gu, Min, Savoldi, Fabio, Chan, Eliza Y. L., Tse, Christine S. K., Lau, Michelle T. W., Wey, Mang C., Hägg, Urban, Yang, YanqiEnlace del recurso
Publicado 2020
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810por Farah, Hussein, Wijesinghe, Susanne N., Nicholson, Thomas, Alnajjar, Fawzeyah, Certo, Michelangelo, Alghamdi, Abdullah, Davis, Edward T., Young, Stephen P., Mauro, Claudio, Jones, Simon W.“…The metabolic profile of isolated synovial fibroblasts in vitro was characterised by lactate secretion, oxygen consumption rate (OCR) and extracellular acidification rate (ECAR) using the Seahorse XF Analyser. …”
Publicado 2022
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811por Li, Ziyin, Mao, Lianzhi, Yu, Bin, Liu, Huahuan, Zhang, Qiuyu, Bian, Zhongbo, Zhang, Xudong, Liao, Wenzhen, Sun, Suxia“…Oxygen consumption rate (OCR) and extracellular acidification rate (ECAR) assays were performed to determine the mitochondrial oxidative phosphorylation (OXPHOS) and glycolysis activity of HCT 116 cells. …”
Publicado 2022
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812por Lin, Zhirong, Li, Zhenzhen, Guo, Zhen, Cao, Yanjun, Li, Jingyan, Liu, Peiqing, Li, Zhuoming“…Results of mitochondrial oxygen consumption rate (OCR) and ATP production measurement demonstrated that BRD2 augmented cardiac metabolism during cardiac hypertrophy. …”
Publicado 2022
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813por Dianiskova, Simona, Rongo, Roberto, Buono, Raffaele, Franchi, Lorenzo, Michelotti, Ambra, D’Antò, VincenzoEnlace del recurso
Publicado 2021
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814por Hadjihambi, Anna, Cudalbu, Cristina, Pierzchala, Katarzyna, Simicic, Dunja, Donnelly, Chris, Konstantinou, Christos, Davies, Nathan, Habtesion, Abeba, Gourine, Alexander V., Jalan, Rajiv, Hosford, Patrick S.“…Ornithine phenylacetate (OP, OCR-002; Ocera Therapeutics, CA, USA) was used as an experimental treatment to reduce plasma ammonia concentration. …”
Publicado 2022
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815“…METHODS: In the present study, we used four spontaneous short-term object exploration tasks over two days: object (OR), object-context (OCR), object-place (OPR), and object-place-context (OPCR) recognition to characterise the ontogeny of episodic-like memory and its components in three commonly used outbred rat strains (Lister Hooded, Long Evans Hooded, and Sprague Dawley). …”
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816“…In addition, Ang II treatment enhanced mitochondrial numbers, ATP production, oxygen consumption rate (OCR) and ROS generation, and reduced MMP (∆Ψm) via CtBP1 in mature 3T3-L1 adipocytes. …”
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817“…The oxygen consumption rate (OCR) and extracellular acidification rate (ECAR) of colon cancer cells were evaluated by a Seahorse XF Extracellular Flux Analyzer. …”
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818por Nocito, Marta Claudia, Avena, Paola, Zavaglia, Lucia, De Luca, Arianna, Chimento, Adele, Hamad, Tarig, La Padula, Davide, Stancati, Davide, Hantel, Constanze, Sirianni, Rosa, Casaburi, Ivan, Pezzi, Vincenzo“…In fact, lactate dehydrogenase, extracellular acidification rate (ECAR), TCA genes and oxygen consumption rate (OCR) were reduced. We instead found an increase in Glutamic-Pyruvic Transaminase (GPT), glutamine antiport transporter SLC1A5 and glutaminase (GLS1), supporting a metabolic rewiring toward glutamine metabolism. …”
Publicado 2023
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819por Sendi, Mohammad S.E., Zendehrouh, Elaheh, Ellis, Charles A., Fu, Zening, Chen, Jiayu, Miller, Robyn L., Mormino, Elizabeth C., Salat, David H., Calhoun, Vince D.“…Next, we calculated the proportion of time each subject spent in each state, called occupancy rate or OCR and frequency of visits. We compared both sFNC and dFNC features across individuals with different genetic risks and found that both sFNC and dFNC are related to AD genetic risk. …”
Publicado 2023
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820por Ghosh, Sujoy, Kruger, Claudia, Wicks, Shawna, Simon, Jacob, Kumar, K. Ganesh, Johnson, William D., Mynatt, Randall L., Noland, Robert C., Richards, Brenda K.“…Metabolite analyses in isolated liver mitochondria from Acads-/- mice during ADP-linked respiration on butyrate demonstrated a reduced oxygen consumption rate (OCR) compared to wild-type, an effect that was not observed with succinate or palmitoylcarnitine substrates. …”
Publicado 2016
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