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1561“…Osteogenesis Imperfecta (OI) is a rare autosomal dominant connective tissue disorder in wich, the bone quality and density is affected. …”
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1562“…The diagnosis of OI in these two patients was made based on clinical, radiological and genetic findings. …”
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1563por Hamatani, Yasuhiro, Nakashima, Junko, Ohta-Ogo, Keiko, Amaki, Makoto, Koga, Masashi, Aoyama, Daisetsu, Marume, Kyohei, Sawada, Kenichiro, Nakashima, Yasuteru, Shibata, Atsushi, Okada, Atsushi, Takahama, Hiroyuki, Hasegawa, Takuya, Sugano, Yasuo, Kanzaki, Hideaki, Ikeda, Yoshihiko, Yasuda, Satoshi, Ishibashi-Ueda, Hatsue, Anzai, Toshihisa“…Meanwhile, he had a COL1A2 gene mutation that is associated with osteogenesis imperfecta (OI), and had some features that were compatible with OI. …”
Publicado 2017
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1564por Starling, Caroline T., Nguyen, Quoc-Bao D., Butler, Ian J., Numan, Mohammed T., Hebert, Adelaide A.“…One subset of dysautonomia includes syndromes of orthostatic intolerance (OI), which primarily affect adolescents and women of childbearing age. …”
Publicado 2021
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1565por Arciaga, Peregrina L., Calmes, Daphne, Windokun, Adejare, Pan, Deyu, Dev, Parvati, Ruff, Henry, Bazargan-Hejazi, Shahrzad“…The VI resulted in substantially achieving similar learning outcomes to OI. This suggests that VI, which has the advantage of being cheaper and more easily scalable than OI, may be an effective remote learning modality for IPE.…”
Publicado 2022
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1566“…Children with osteogenesis imperfecta (OI) are at an increased risk of olecranon fractures. …”
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1567por Schindeler, Aaron, Lee, Lucinda R, O'Donohue, Alexandra K, Ginn, Samantha L, Munns, Craig F“…Osteogenesis imperfecta (OI) describes a series of genetic bone fragility disorders that can have a substantive impact on patient quality of life. …”
Publicado 2022
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1568“…This paper aims to provide an overview of open innovation (OI) and the food industry, examine the main drivers of this model in the food industry, and consider the impact of applying open innovation strategies by companies. …”
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1569por Neri Morales, Constanza, Silva Amaro, Alejandra, Cardona, José D, Bendeck, Joanna L, Cifuentes Gaitan, Karen, Ferrer Valencia, Valentina, Domínguez, María T, Quevedo, María L, Fernández, Isabel, Celis Regalado, Luis G“…We present four cases of OI, one case with type I, two cases with type II, and one case with type III. …”
Publicado 2023
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1570por Koumakis, Eugénie, Cormier-Daire, Valérie, Dellal, Azeddine, Debernardi, Marc, Cortet, Bernard, Debiais, Françoise, Javier, Rose-Marie, Thomas, Thierry, Mehsen-Cetre, Nadia, Cohen-Solal, Martine, Fontanges, Elisabeth, Laroche, Michel, Porquet-Bordes, Valérie, Marcelli, Christian, Benachi, Alexandra, Briot, Karine, Roux, Christian, Cormier, Catherine“…Fracture occurrence during pregnancy and post-partum, and its determinants, remain poorly known in Osteogenesis Imperfecta (OI). The aim of this study was to characterize fractures that occurred during pregnancy and post-partum in OI patients. …”
Publicado 2022
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1571por Sundararajan, Silvampatti Ramasamy, Ramakanth, Rajagopalakrishnan, Jha, Amit Kumar, Rajasekaran, Shanmuganathan“…IO graft harvesting technique is better in terms of graft harvest time and cosmetics and yields longer graft; however, area of paraesthesia, though not significant, was two-fold higher than the OI technique at 1-year follow-up. CLINICAL RELEVANCE: IO graft harvest technique would enable the surgeon to adopt quicker graft harvest, smaller surgical scar and lengthier graft than the OI technique. …”
Publicado 2022
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1572por Jones, Bruce M, Cleveland, Kerry O, Gonzalez, Pedro L, Rappo, Urania, Riccobene, Todd, Lyles, Rosie D“…Of 957 evaluable patients, 815 (85.2%) had ABSSSI, 48 (5.0%) had BSI, 87 (9.0%) had BJI, and 7 (0.7%) had OI. Clinical success was achieved in 91.7%, 89.6%, 86.2%, and 100% of patients with ABSSSI, BSI, BJI, and OI, respectively (Figure 1). …”
Publicado 2022
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1573por Waqas, Fakhar H., Shehata, Mahmoud, Elgaher, Walid A. M., Lacour, Antoine, Kurmasheva, Naziia, Begnini, Fabio, Kiib, Anders E., Dahlmann, Julia, Chen, Chutao, Pavlou, Andreas, Poulsen, Thomas B., Merkert, Sylvia, Martin, Ulrich, Olmer, Ruth, Olagnier, David, Hirsch, Anna K. H., Pleschka, Stephan, Pessler, Frank“…Ligand–target modelling predicted covalent binding of all three NRF2 activators and SEL to the active site of XPO1 involving the critical Cys528. SEL and 4OI manifested the highest binding energies, whereby the 4-octyl tail of 4OI interacted extensively with the hydrophobic groove of XPO1, which binds nuclear export sequences on cargo proteins. …”
Publicado 2023
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1574por Sałacińska, Kinga, Pinkier, Iwona, Rutkowska, Lena, Chlebna-Sokół, Danuta, Jakubowska-Pietkiewicz, Elżbieta, Michałus, Izabela, Kępczyński, Łukasz, Salachna, Dominik, Jamsheer, Aleksander, Bukowska-Olech, Ewelina, Jaszczuk, Ilona, Jakubowski, Lucjusz, Gach, Agnieszka“…Osteogenesis imperfecta (OI) is a rare genetic disorder demonstrating considerable phenotypic and genetic heterogeneity. …”
Publicado 2021
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1575“…Health systems that were primarily investor owned had an OI that was 0.56 SD higher than those that were not investor owned. …”
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1576por Noda, Aoi, Ishikuro, Mami, Obara, Taku, Murakami, Keiko, Ueno, Fumihiko, Matsuzaki, Fumiko, Onuma, Tomomi, Watanabe, Zen, Shiga, Naomi, Iwama, Noriyuki, Hirotaka, Hamada, Otsuka, Tatsui, Tachibana, Masahito, Tomita, Hiroaki, Saito, Masatoshi, Sugawara, Junichi, Kure, Shigeo, Yaegashi, Nobuo, Kuriyama, Shinichi“…RESULTS: Of 9655 mother–child pairs, 273 (2.8%) and 487 (5.0%) were conceived through OI/AIH and ART, respectively. The odds of having developmental delays at 2 years of age were higher in children conceived through OI/AIH (OR, 1.36; 95% CI 1.00 to 1.85) and ART (OR, 1.36; 95% CI 1.07 to 1.72) than in those conceived naturally. …”
Publicado 2022
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1577“…PURPOSE: Nearly 85%-90% of osteogenesis imperfecta (OI) cases are caused by autosome dominant mutations of COL1A1 and COL1A2 genes, of which de novo mutations cover a large proportion, whereas their characteristics remain to be elucidated. …”
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1578por Wang, Luyao, Yu, Yuanyuan, Ni, Shuaijian, Li, Dijie, Liu, Jin, Xie, Duoli, Chu, Hang Yin, Ren, Qing, Zhong, Chuanxin, Zhang, Ning, Li, Nanxi, Sun, Meiheng, Zhang, Zong-Kang, Zhuo, Zhenjian, Zhang, Huarui, Zhang, Shu, Li, Mei, Xia, Weibo, Zhang, Zhenlin, Chen, Lin, Shang, Peng, Pan, Xiaohua, Lu, Aiping, Zhang, Bao-Ting, Zhang, Ge“…Rationale: Sclerostin inhibition demonstrated bone anabolic potential in osteogenesis imperfecta (OI) mice, whereas humanized therapeutic sclerostin antibody romosozumab for postmenopausal osteoporosis imposed clinically severe cardiac ischemic events. …”
Publicado 2022
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1579por Shilpasree, AS, Kulkarni, Vinuta B., Shetty, Praveenkumar, Bargale, Anil, Goni, Mallikarjun, Oli, Ajaykumar, Sarathkumar, E, Patil, Vidya S., Desai, Rathnamala M.“…On regression analysis adjusted for age and BMI, vitamin D was an independent predictor of successful pregnancy after OI (P = 0.09). CONCLUSION: Circulating vitamin D levels influence the endometrial HOXA10 gene expression, and this may be reflected on the reproductive outcome of infertile PCOS patients undergoing OI.…”
Publicado 2022
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1580“…BACKGROUND: Although Osteogenesis Imperfecta (OI) affects the connective tissue, pulmonary function might be compromised because of thoracic deformities. …”
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