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1por Subrahmanyam, Ramesh, Du, Hansen, Ivanova, Irina, Chakraborty, Tirtha, Ji, Yanhong, Zhang, Yu, Alt, Frederick W., Schatz, David G., Sen, Ranjan“…These include timing (V(H) recombination follows D(H) recombination), precision (V(H)s recombine only to DJ(H) junctions) and allele specificity (V(H) recombination is restricted to DJ(H) recombined alleles). …”
Publicado 2012
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2por Repici, Mariaelena, Straatman, Kornelis R., Balduccio, Nadia, Enguita, Francisco J., Outeiro, Tiago F., Giorgini, Flaviano“…Here, we use bimolecular fluorescence complementation to study DJ-1 dimerization and find not only that DJ-1 forms homodimers in living cells but that most PD causative DJ-1 mutations disrupt this process, including the L166P, M26I, L10P, and P158∆ mutations. …”
Publicado 2012
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3por Mazza, Melissa Conti, Shuck, Sarah C., Lin, Jiusheng, Moxley, Michael A., Termini, John, Cookson, Mark R., Wilson, Mark A.“…The steady‐state kinetics of DJ‐1 acting on reversible hemithioacetal substrates are fitted adequately with a computational kinetic model that requires only a DJ‐1 glyoxalase activity, supporting the conclusion that deglycation is an apparent rather than a true activity of DJ‐1. …”
Publicado 2022
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