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20121por Labella, Alejandro M., Garcia-Rosado, Esther, Bandín, Isabel, Dopazo, Carlos P., Castro, Dolores, Alonso, M. Carmen, Borrego, Juan J.“…To study the biological functions of detected DEGs involved in NNV infection, a gene ontology (GO) enrichment analysis was performed. Different GO profiles were obtained in the following subclasses: (i) biological process; (ii) cellular component; and (iii) molecular function, for each viral strain tested. …”
Publicado 2018
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20122por Shen, Jie, Cao, Beibei, Wang, Yatao, Ma, Chenshen, Zeng, Zhuo, Liu, Liang, Li, Xiaolan, Tao, Deding, Gong, Jianping, Xie, Daxing“…Gene expression profiling was used to screen differently expressed genes, and gene ontology enrichment was performed using DAVID software. …”
Publicado 2018
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20123por Wang, Xing, Cheng, Chunyan, Zhang, Kaijing, Tian, Zhen, Xu, Jian, Yang, Shuqiong, Lou, Qunfeng, Li, Ji, Chen, Jin-Feng“…Physiological observations showed abnormal development of giant cells and M. incognita in IL10–1, which were the primary differences compared with CC3. Furthermore, Gene ontology (GO) analysis revealed that genes encoding cell wall proteins were up-regulated in IL10–1 and that the highly expressed lipid transfer protein gene (Csa6G410090) might be the principal regulator of this up-regulation. …”
Publicado 2018
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20124por Chou, Hsien-Chao, Acevedo-Luna, Natalia, Kuhlman, Julie A., Schneider, Stephan Q.“…Our database also includes additional stages over the P. dumerilii life cycle and provides access to the expression data of 17,213 genes (31,806 transcripts) along with annotation information sourced from Swiss-Prot, Gene Ontology, KEGG pathways, Pfam domains, TmHMM, SingleP, and EggNOG orthology. …”
Publicado 2018
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20125“…Furthermore, we demonstrated 197 upregulated, and 373 downregulated Gene Ontology terms and 176 significantly enriched pathways, such as the mitogen-activated protein kinase (MAPK) pathway. …”
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20126“…Herein we examined how feeding natural and artificial diets shapes transcription in the abdomen of the honey bee, and how transcription shifts in combination with Nosema parasitism. RESULTS: Gene ontology enrichment revealed that, compared with poor diet (carbohydrates [C]), bees fed pollen (P > C), Bee-Pro (B > C), and MegaBee (M > C) showed a broad upregulation of metabolic processes, especially lipids; however, pollen feeding promoted more functions, and superior proteolysis. …”
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20127“…Co-expression of miRNAs, lncRNAs and mRNAs was selected to construct mRNA-miRNA-lncRNA interaction networks. Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment analyses were performed for the DEGs. …”
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20128por Houtman, Miranda, Ekholm, Louise, Hesselberg, Espen, Chemin, Karine, Malmström, Vivianne, Reed, Ann M., Lundberg, Ingrid E., Padyukov, Leonid“…Of these, 44 genes were expressed significantly higher in CD8+ T cells from patients with PM, and 132 genes were expressed significantly higher in CD8+ T cells from patients with DM (FDR < 0.05, model adjusted for age, sex, and RIN). Gene Ontology analysis showed that genes differentially expressed in CD8+ T cells are involved in lymphocyte migration and regulation of T-cell differentiation. …”
Publicado 2018
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20129“…Using protein-protein interaction information from the Search Tool for the Retrieval of Interacting Genes database, disease modules were constructed for gastric cancer using Cytoscape software. In the Gene Ontology analysis of biology processes, upregulated genes were significantly enriched in ‘extracellular matrix organization’, ‘cell adhesion’ and ‘inflammatory response’, whereas downregulated DEGs were significantly enriched in ‘xenobiotic metabolic process’, ‘oxidation-reduction process’ and ‘steroid metabolic process’. …”
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20130por Chen, Linfeng, Ding, Xianlong, Zhang, Hao, He, Tingting, Li, Yanwei, Wang, Tanliu, Li, Xiaoqiang, Jin, Ling, Song, Qijian, Yang, Shouping, Gai, Junyi“…Moreover, 83 miRNAs were predicted from the differentially expressed circRNAs, some of which were strongly related to pollen development and male fertility; The functions of miRNA targets were analyzed using Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG), and the target mRNAs were significantly enriched in signal transduction and programmed cell death. …”
Publicado 2018
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20131“…A total of 10,852 and 10,902 common genes and 667 and 868 endemic genes were identified from the two monospore strains, respectively. The Gene Ontology (GO) and KAAS (KEGG Automatic Annotation Serve) enrichment analyses showed that the endemic genes performed different functions. …”
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20132Prediction of Target Genes and Pathways Associated With Cetuximab Insensitivity in Colorectal Cancerpor Yu, Chaoran, Hong, Hiju, Lu, Jiaoyang, Zhao, Xuan, Hu, Wenjun, Zhang, Sen, Zong, Yaping, Mao, Zhihai, Li, Jianwen, Wang, Mingliang, Feng, Bo, Sun, Jing, Zheng, Minhua“…Differentially expressed genes were identified between cetuximab-responsive patients and nonresponders, annotated by gene ontology, Kyoto Encyclopedia of Genes and Genomes pathway analysis, and further analyzed by protein–protein interaction networks. …”
Publicado 2018
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20133por Horodyska, Justyna, Wimmers, Klaus, Reyer, Henry, Trakooljul, Nares, Mullen, Anne Maria, Lawlor, Peadar G., Hamill, Ruth M.“…High-FE pigs also had reduced intramuscular fat content and improved nutritional profile in terms of fatty acid composition. CONCLUSIONS: Ontology analysis revealed enhanced activity of adaptive immunity and phagocytes in high-FE pigs suggesting more efficient conserving of resources, which can be utilised for other important biological processes. …”
Publicado 2018
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20134por Cai, Kai-Teng, Feng, Cai-Xia, Zhao, Jin-Che, He, Rong-Quan, Ma, Jie, Zhong, Jin-Cai“…The distinguishability of precursor miR-203a and miR-203a-3p in BC tissue and adjacent breast tissue was assessed using receiver operating characteristic (ROC) and summarized ROC (sROC) approaches. In addition, gene ontology (GO) enrichment, Kyoto Encyclopedia of Genes and Genomes pathway analysis and protein-protein interaction analysis were performed to determine the potential molecular mechanism of miR-203a-3p in BC. …”
Publicado 2018
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20135por Cross, Ismael, Portela-Bens, Silvia, García-Angulo, Aglaya, Merlo, Manuel A., Rodríguez, María E., Liehr, Thomas, Rebordinos, Laureana“…As a result, genes associated with abiotic adaptation, such as metallothioneins, have been positioned in the genome. The gene ontology analysis has also shown many molecular functions related to metal ion binding, a phenomenon associated with detoxification processes that are characteristic in oysters. …”
Publicado 2018
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20136por Gao, Xiaojian, Pi, Daming, Chen, Nan, Li, Xixi, Liu, Xiaodan, Yang, Hui, Wei, Wanhong, Zhang, Xiaojun“…The differently expressed genes (DEGs) of the starved strain were thereby identified, including 251 up-regulated genes and 272 down-regulated genes in comparison with the non-starved strain. Gene Ontology (GO) analysis and Kyto Encyclopedia Genes and Genomes (KEGG) enrichment analysis of DEGs were also analyzed. …”
Publicado 2018
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20137por Zhang, Yue, Zhang, Hui, An, Minghui, Zhao, Bin, Ding, Haibo, Zhang, Zining, He, Youwen, Shang, Hong, Han, Xiaoxu“…The circRNA profile and circRNA-associated-ceRNA network in EHI were analyzed with the integrated data of RNA-Seq and miRNA-Seq. Gene ontology (GO) analysis was used to annotate the circRNAs involved in the circRNA-associated-ceRNA networks. …”
Publicado 2018
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20138por Zhang, Ying, Wang, Kuanyu, Zhao, Zheng, Sun, Si, Zhang, Kenan, Huang, Ruoyu, Zeng, Fan, Hu, Huimin“…Relationships between ADAR3 expression and prognosis-related genomic alteration, outcome and gene ontology analysis were investigated. Moreover, the characteristic of GRIA2(Q607R) editing in gliomas has been investigated. …”
Publicado 2018
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20139“…The RobustRankAggreg (RRA) method was utilized to integrate and analyze the four datasets to obtain integrated differentially expressed genes (DEGs), and the gene ontology (GO) functional annotation and Kyoto encyclopedia of genes and genomes (KEGG) pathway analysis were performed. …”
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20140por Chen, Guohu, Ye, Xinyu, Zhang, Shengyun, Zhu, Shidong, Yuan, Lingyun, Hou, Jinfeng, Wang, Chenggang“…Bioinformatics analysis detected 4430 differentially expressed genes (DEGs) between the fertile and sterile flower buds. Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment analyses were performed to better understand the functions of these DEGs. …”
Publicado 2018
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