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20141por Li, Zhen, Yao, Jian-Ni, Huang, Wen-Ting, He, Rong-Quan, Ma, Jie, Chen, Gang, Wei, Qing-Jun“…On the basis of the Database for Annotation, Visualization and Integrated Discovery, version 6.8, a study of gene ontology (GO) enrichment and the Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway knowledge base was conducted to explore the biological value of miR-542-3p in OS. …”
Publicado 2019
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20142por Zhang, Fuping, Liu, Xiaoping, Zhang, Aidi, Jiang, Zhonglin, Chen, Luonan, Zhang, Xiujun“…Composed of three major subnetworks, a gene regulatory network with 150 nodes and 225 edges was found to be highly correlated with flowering transition. The gene ontology (GO) annotation of pathway enrichment analysis revealed that the identified genes are enriched in the catalytic activity, metabolic process and cellular process. …”
Publicado 2019
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20143por Park, Seongjun, Son, Sungwon, Shin, Myungju, Fujii, Noriyuki, Hoshino, Takuji, Park, SeonJoo“…A total of 4510 microsatellite-containing transcripts had Gene Ontology (GO) annotations, and Kyoto Encyclopedia of Genes and Genomes (KEGG) analysis identified 124 pathways with significant scores. …”
Publicado 2019
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20144por Silva-Vignato, Bárbara, Coutinho, Luiz L., Poleti, Mirele D., Cesar, Aline S. M., Moncau, Cristina T., Regitano, Luciana C. A., Balieiro, Júlio C. C.“…The enrichment analysis performed by DAVID and WebGestalt (FDR 5%) identified eight Gene Ontology (GO) terms and three KEGG pathways in the Green Yellow module, mostly associated with immune response and inflammatory mechanisms. …”
Publicado 2019
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20145por Kang, Xincong, Liu, Chichuan, Shen, Pengyuan, Hu, Liqin, Lin, Runmao, Ling, Jian, Xiong, Xingyao, Xie, Bingyan, Liu, Dongbo“…The DEGs identified in GO (Gene ontology) and KEGG (Kyoto Encyclopedia of Genes and Genomes) pathways were primarily located in carbon and nitrogen metabolism and nucleolus, ribosome, and rRNA processing. …”
Publicado 2019
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20146por Su, Yachun, Xiao, Xinhuan, Ling, Hui, Huang, Ning, Liu, Feng, Su, Weihua, Zhang, Yuye, Xu, Liping, Muhammad, Khushi, Que, Youxiong“…A total of 309 target genes were predicted in sugarcane, corresponding to 97 known miRNAs and 112 novel miRNAs, and 337 degradation sites, suggesting that miRNAs can efficiently direct cleavage at multiple sites in the predicted target mRNAs. Gene Ontology (GO) annotation and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analysis indicated that the predicted target genes were involved in various regulatory processes, such as signal transduction mechanisms, inorganic ion transport and metabolism, defense mechanisms, translation, posttranslational modifications, energy production and conversion, and glycerolipid metabolism. qRT-PCR analysis of the expression level of 13 predicted target genes and their corresponding miRNAs revealed that there was no obvious negative regulatory relationship between miRNAs and their target genes. …”
Publicado 2019
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20147“…The down-regulated genes annotated to Gene Ontology (GO) terms showed anion transport, synaptic vesicle localisation, organic anion transport, secretion and signal release as the five most enriched terms. …”
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20148por Li, Shaomei, Zheng, Xinting, Nie, Yangfan, Chen, Wenshuo, Liu, Zhiwei, Tao, Yingfeng, Hu, Xuewen, Hu, Yong, Qiao, Haisheng, Qi, Quanqing, Pei, Quanbang, Cai, Danzhuoma, Yu, Mei, Mou, Chunyan“…To understand the molecular mechanisms underlying morphogenesis of apocrine sweat glands in sheepskin, transcriptome analyses were conducted to reveal 1631 differentially expressed genes that were mainly enriched in three functional groups (cellular component, molecular function and biological process), particularly in gland, epithelial, hair follicle and skin development. There were 7 Gene Ontology (GO) terms enriched in epithelial cell migration and morphogenesis of branching epithelium that were potentially correlated with the wool follicle peg elongation. …”
Publicado 2019
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20149por Xie, Xiaowei, Zhao, Jingan, Xie, Lixin, Wang, Haiyan, Xiao, Yan, She, Yingjia, Ma, Lingyun“…First, isobaric tags for relative and absolute quantization (iTRAQ) and weighted gene co-expression network analysis (WGCNA) were used to identify important differentially expressed proteins. Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analyses were used to study the biological functions of differentially expressed proteins. …”
Publicado 2019
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20150por Cao, Xinyou, Hu, Liqin, Chen, Xueyan, Zhang, Rongzhi, Cheng, Dungong, Li, Haosheng, Xu, Zhaoshi, Li, Liancheng, Zhou, Yongbin, Liu, Aifeng, Song, Jianming, Liu, Cheng, Liu, Jianjun, Zhao, Zhendong, Chen, Ming, Ma, Youzhi“…We conducted a comparative analysis of these DEGs under low-K(+) stress conditions and discovered 248 common DEGs for potassium deprivation among foxtail millet, rice and Arabidopsis. Further Gene Ontology (GO) enrichment analysis identified a series of candidate genes that may involve in K(+)-deficient response and in intersection of molecular functions among foxtail millet, rice and Arabidopsis. …”
Publicado 2019
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20151por da Silva, Vinicius H., Laine, Veronika N., Bosse, Mirte, Oers, Kees van, Dibbits, Bert, Visser, Marcel E., M. A. Crooijmans, Richard P., Groenen, Martien A. M.“…We observed frequency-dependent enrichment of these breakpoints at homologous regions, CpG sites and AT-rich intervals. A gene ontology enrichment analyses showed that CNVs are enriched in genes underpinning neural, cardiac and ion transport pathways. …”
Publicado 2018
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20152por Dmitriev, Alexey A., Krasnov, George S., Rozhmina, Tatiana A., Zyablitsin, Alexander V., Snezhkina, Anastasiya V., Fedorova, Maria S., Pushkova, Elena N., Kezimana, Parfait, Novakovskiy, Roman O., Povkhova, Liubov V., Smirnova, Marina I., Muravenko, Olga V., Bolsheva, Nadezhda L., Kudryavtseva, Anna V., Melnikova, Nataliya V.“…Ion homeostasis, oxidoreductase activity, cell wall, and response to stress Gene Ontology terms were the most affected by unfavorable pH and Zn deficiency both in tolerant and sensitive flax cultivars. …”
Publicado 2019
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20153por Mirdar Mansuri, Raheleh, Shobbar, Zahra-Sadat, Babaeian Jelodar, Nadali, Ghaffari, Mohammad Reza, Nematzadeh, Ghorban-Ali, Asari, Saeedeh“…RESULTS: A total of 1714 and 2670 genes were found differentially expressed (DEGs) under salt stress compared to normal conditions in FL478 and IR29, respectively. Gene ontology analysis revealed the enrichment of transcripts involved in salinity response, regulation of gene expression, and transport in both genotypes. …”
Publicado 2019
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20154por Chen, Yu-Ji, Guo, Yi-Nan, Shi, Ke, Huang, Hui-Mei, Huang, Shu-Ping, Xu, Wen-Qing, Li, Zu-Yun, Wei, Kang-Lai, Gan, Ting-Qing, Chen, Gang“…Furthermore, we investigated the biological function of miR-144-3p by Gene Ontology (GO), Kyoto Encyclopedia of Genes and Genomes (KEGG) analyses. …”
Publicado 2019
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20155“…Differentially expressed lncRNAs, miRNAs and mRNAs were unveiled by package edgeR of R, and lncRNA-miRNA-mRNA ceRNA network was constructed by integrating the miRNA target information and the expression data of lncRNAs, miRNAs and mRNAs. Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analyses of aberrantly expressed mRNAs were performed to identify the related biological functions and pathologic pathways, and protein-protein interaction (PPI) network was constructed by STRING database. …”
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20156“…Subsequently, all of the differentially expressed genes (DEGs) were subjected to gene ontology function and Kyoto encyclopedia of genes and genomes pathway enrichment analysis. …”
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20157“…Co-expressed gene sets (ranging from 100–1000 genes) associated with each Sirt3 probe were evaluated using the previously developed literature-derived cohesion p-value (LPv) and benchmarked against ‘gold standards’ derived from proteomic studies or Gene Ontology classifications. We found that the maximal F-measure was obtained at an average window size of 535 genes. …”
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20158por Guo, Juan, He, Keli, Zeng, Hui, Shi, Yu, Ye, Peng, Zhou, Qian, Pan, Zhongya, Long, Xinghua“…Next-generation sequencing was used to determine the miRNA expression profiles in these cell lines. Subsequently, Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analyses were performed to determine the biological functions of differentially expressed miRNAs. …”
Publicado 2019
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20159por Spetz, Johan, Langen, Britta, Rudqvist, Nils-Petter, Parris, Toshima Z., Shubbar, Emman, Dalmo, Johanna, Wängberg, Bo, Nilsson, Ola, Helou, Khalil, Forssell-Aronsson, Eva“…Analysis of the biological effects of transcriptional regulation was performed using the Gene Ontology database and Ingenuity Pathway Analysis. Transcriptional analysis of the tumors revealed two stages of pathway regulation for the priming schedule (up to 1 week and around 1 month) which differed distinctly from cellular responses observed after monotherapy. …”
Publicado 2019
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20160por Xu, Fen, Xiang, Qinqin, Huang, Jiuzuo, Chen, Qianlong, Yu, Nanze, Long, Xiao, Zhou, Zhou“…The RNA-seq bioinformatics analysis predicted 1119 gene targets of the top 30 exosomal miRNAs in Gene Ontology (GO) analysis and Kyoto encyclopedia of genes and genomes (KEGG) pathway analysis, and the pathway involved in the angiogenesis was among the top KEGG pathways. …”
Publicado 2019
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