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  1. 20201
    “…Focusing on gene expression we found several significant messenger RNAs (mRNAs) between tumor and normal tissue and a Gene Ontology (GO) analysis revealed that these changes were mainly related to cell cycle and metabolism. …”
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    Comprehensive transcriptomic analyses of tissue, serum, and serum exosomes from hepatocellular carcinoma patients
  2. 20202
    “…FT3 value served as an independent predictor for neurological outcomes for which the cut-off value of FT3 was 4.38 pmol/l. Gene ontology (GO) analysis showed that the biological function of DEGs was mainly enriched in multicellur organism, neuron differentiation and cellular response to hypoxia. …”
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    Low free triiodothyronineis predicts worsen neurological outcome of patients with acute ischemic stroke: a retrospective study with bioinformatics analysis
  3. 20203
    “…Data integration of the miRNA/mRNA profiles with gene ontology (GO) analysis and bioinformatics was performed to detect potential miRNA-mRNA regulatory circuits. …”
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    MicroRNA-92a-1–5p increases CDX2 by targeting FOXD1 in bile acids-induced gastric intestinal metaplasia
  4. 20204
    “…Here, using an affinity purification-coupled mass spectrometry (AP-MS) strategy, 591 host proteins were identified as interactors of LASV GP. Gene ontology analysis was performed to functionally annotate these proteins, and the oligosaccharyltransferase (OST) complex was highly enriched. …”
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    Comprehensive Interactome Analysis Reveals that STT3B Is Required for N-Glycosylation of Lassa Virus Glycoprotein
  5. 20205
    por Song, Wei, Fu, Tao
    Publicado 2019
    “…The R package “clusterProfiler” was used to evaluate the Gene Ontology (GO) annotations of the differentially expressed mRNAs and the Kyoto Encyclopedia of Genes and Genomes (KEGG) pathways. …”
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    Circular RNA-Associated Competing Endogenous RNA Network and Prognostic Nomogram for Patients With Colorectal Cancer
  6. 20206
    “…Three hundred forty-nine differentially expressed genes (DEGs) were screened between OC tissues and OV tissues via GEO2R and online Venn software, followed by KEGG pathway and gene ontology (GO) enrichment analysis. The enriched functions and pathways of these DEGs contain male gonad development, cellular response to transforming growth factor beta stimulus, positive regulation of transcription from RNA polymerase II promoter, calcium independent cell-cell adhesion via plasma membrane cell adhesion molecules, extracellular matrix organization, pathways in cancer, cell cycle, cell adhesion molecules, PI3K-AKT signaling pathway, and progesterone mediated oocyte maturation. …”
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    Identification of key biomarkers associated with development and prognosis in patients with ovarian carcinoma: evidence from bioinformatic analysis
  7. 20207
    “…In order to predict the potential biological functions of five-miRNA signature, target genes of these five miRNAs were analyzed by Kyoto Encyclopedia of Genes and Genomes (KEGG) signaling pathway and Gene Ontology (GO) enrichment analysis. The top 10 hub genes (ESR1, ADCY9, MEF2C, NRXN1, ADCY5, FGF2, KITLG, GATA1, GRIA1, KAT2B) of target genes in protein protein interaction (PPI) network were screened by string database and Cytoscape 3.6.1 (plug-in cytoHubba). …”
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    A Five-microRNA Signature as Prognostic Biomarker in Colorectal Cancer by Bioinformatics Analysis
  8. 20208
    “…Analysis through a protein-protein interaction (PPI) network and the Gene Ontology database was performed by using the Cytoscape and DAVID online tools, respectively. …”
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    Downregulation of the Helicase Lymphoid-Specific (HELLS) Gene Impairs Cell Proliferation and Induces Cell Cycle Arrest in Colorectal Cancer Cells
  9. 20209
    “…Differentially expressed genes were further characterized for global responses using the GEDI tool, gene networks and for Gene Ontology (GO) enrichment. Results: Differential gene expression analysis revealed only one differentially expressed gene (AT4G21560, VPS28-1 a vacuolar protein) across all gravity conditions using FDR correction (q < 0.05). …”
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    RNAseq Analysis of the Response of Arabidopsis thaliana to Fractional Gravity Under Blue-Light Stimulation During Spaceflight
  10. 20210
    “…Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analysis was performed using the “clusterProfiler” package. Gene ontology and protein–protein interaction (PPI) networks were analyzed for the differentially expressed mRNAs using the “STRING” database. …”
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    Identification and analysis of long non-coding RNA related miRNA sponge regulatory network in bladder urothelial carcinoma
  11. 20211
    “…IMPC-specific gene expression profiles were explored using microarrays data from the Gene Expression Omnibus (GEO) database. Gene ontology (GO) and Kyoto Encyclopedia of Genes and Genomes pathway (KEGG) enrichment analyses were performed. …”
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    A Competing Nomogram to Predict Survival Outcomes in Invasive Micropapillary Breast Cancer
  12. 20212
    “…Additionally, we also conducted analyses of gene ontology, and expression profiles in silico, allowing identification of F-box gene members potentially involved in hormone signal transduction. …”
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    Genome-wide analysis and characterization of F-box gene family in Gossypium hirsutum L
  13. 20213
    “…The identified proteins were annotated and analyzed by Gene Ontology (GO), Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analysis and protein-protein interaction (PPI) networks analysis. …”
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    Proteomic analysis of the second-generation merozoites of Eimeria tenella under nitromezuril and ethanamizuril stress
  14. 20214
    “…RESULTS: A total of 418 differentially expressed genes (DEGs) were identified specifically in the CGN18423 response process. Gene Ontology (GO) analysis revealed that GO terms including “plasma membrane (GO_Component)”, “histidine decarboxylase activity (GO_Function)”, and “carboxylic acid metabolic process (GO_Process)”, as well as other 10 GO terms, were significantly enriched. …”
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    Transcriptome profiling reveals the response process of tomato carrying Cf-19 and Cladosporium fulvum interaction
  15. 20215
    “…Functional annotation of PHI genes was carried out using Web Gene Ontology Annotation Plot (WEGO) and was used for selecting candidate PHI genes related to cell wall degradation of G. boninense NJ3. …”
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    Insight into plant cell wall degradation and pathogenesis of Ganoderma boninense via comparative genome analysis
  16. 20216
    “…Among them, 38,905 unigenes had homology with known genes, 18,239 were assigned to 54 gene ontology (GO) categories and 18,909 were assigned to 25 clusters of orthologous groups (COG) categories. …”
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    Transcriptomic analyses of Pinus koraiensis under different cold stresses
  17. 20217
    “…Arginine biosynthesis was found to be the most significant pathway involved in the AIH process. During the Gene Ontology (GO) analysis, most DEPs were found to be involved in the binding, cellular, and metabolic processes. …”
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    Plasma proteomic analysis of autoimmune hepatitis in an improved AIH mouse model
  18. 20218
    “…The selection of new potential drug targets was made by methods of NetP (DIAMOnD algorithm, enrichment analysis of KEGG pathways and biological processes of Gene Ontology) and manual expert analysis. The structures of 1976 phytomolecules from the 573 Indian medicinal plants traditionally used for the treatment of dementia and vascular diseases were used for computational estimation of their interactions with new predicted VaD-related drug targets by RevP approach based on PASS (Prediction of Activity Spectra for Substances) software. …”
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    Combined network pharmacology and virtual reverse pharmacology approaches for identification of potential targets to treat vascular dementia
  19. 20219
    por McLean, Samuel A., Ressler, Kerry, Koenen, Karestan Chase, Neylan, Thomas, Germine, Laura, Jovanovic, Tanja, Clifford, Gari D., Zeng, Donglin, An, Xinming, Linnstaedt, Sarah, Beaudoin, Francesca, House, Stacey, Bollen, Kenneth A., Musey, Paul, Hendry, Phyllis, Jones, Christopher W., Lewandowski, Christopher, Swor, Robert, Datner, Elizabeth, Mohiuddin, Kamran, Stevens, Jennifer S., Storrow, Alan, Kurz, Michael Christopher, McGrath, Meghan E., Fermann, Gregory J., Hudak, Lauren A., Gentile, Nina, Chang, Anna Marie, Peak, David A., Pascual, Jose L., Seamon, Mark J., Sergot, Paulina, Peacock, W. Frank, Diercks, Deborah, Sanchez, Leon D., Rathlev, Niels, Domeier, Robert, Haran, John Patrick, Pearson, Claire, Murty, Vishnu P., Insel, Thomas R., Dagum, Paul, Onnela, Jukka-Pekka, Bruce, Steven E., Gaynes, Bradley N., Joormann, Jutta, Miller, Mark W., Pietrzak, Robert H., Buysse, Daniel J., Pizzagalli, Diego A., Rauch, Scott L., Harte, Steven E., Young, Larry J., Barch, Deanna M., Lebois, Lauren A. M., van Rooij, Sanne J. H., Luna, Beatriz, Smoller, Jordan W., Dougherty, Robert F., Pace, Thaddeus W. W., Binder, Elisabeth, Sheridan, John F., Elliott, James M., Basu, Archana, Fromer, Menachem, Parlikar, Tushar, Zaslavsky, Alan M., Kessler, Ronald
    Publicado 2019
    “…These limitations in classification and ontology slow the discovery of pathophysiologic mechanisms, biobehavioral markers, risk prediction tools, and preventive/treatment interventions. …”
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    The AURORA Study: A Longitudinal, Multimodal Library of Brain Biology and Function after Traumatic Stress Exposure
  20. 20220
    “…Gene set enrichment analysis for different diet-tissue combinations revealed a diverse set of pathways and gene ontology (GO) terms (two-sample t-test, FDR < 0.05). …”
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    Diverse biological processes coordinate the transcriptional response to nutritional changes in a Drosophila melanogaster multiparent population
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