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20441por Yu, Ying, Tan, Panli, Zhuang, Zhenchao, Wang, Zhejiong, Zhu, Linchao, Qiu, Ruyi, Xu, Huaxi“…RESULTS: There were 80 proteins differentially expressed between PCOS patients and controls significantly, including 54 downregulated and 26 upregulated proteins. Gene ontology and Kyoto Encyclopedia of Genes and Genomes analysis showed that downregulated proteins were enriched in platelet degranulation, cell adhesion, cell activation, blood coagulation, hemostasis, defense response and inflammatory response terms; upregulated proteins were enriched in cofactor catabolic process, hydrogen peroxide catabolic process, antioxidant activity, cellular oxidant detoxification, cellular detoxification, antibiotic catabolic process and hydrogen peroxide metabolic process. …”
Publicado 2021
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20442por Kubota, Yukihiro, Ohnishi, Yuto, Hamasaki, Tasuku, Yasui, Gen, Ota, Natsumi, Kitagawa, Hiromu, Esaki, Arashi, Fahmi, Muhamad, Ito, Masahiro“…Combined analysis of genetic interactions and gene ontology of these corepressors indicate a prominent overlapping role among SIN-3, SPR-1, and LET-418 and between SIN-3 and SPR-1. …”
Publicado 2021
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20443por Zhang, Lili, Qu, Sihao, Wang, Lu, Wang, Chunguo, Yu, Qinghe, Zhang, Zhimin, Diao, Yirui, Zhang, Binbin, Li, Yadong, Shi, Yuanyuan, Wang, Peng“…Changes in the profiles of the expressed proteins were analyzed using the bioinformatics tools Gene Ontology (GO) and the Kyoto Encyclopedia of Genes and Genomes (KEGG). …”
Publicado 2021
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20444por Fang, Yifei, Hao, Xinyu, Xu, Zhong, Sun, Hao, Zhao, Qingbo, Cao, Rui, Zhang, Zhe, Ma, Peipei, Sun, Yanxiao, Qi, Zengmin, Wei, Qingkui, Wang, Qishan, Pan, Yuchun“…A total of six significant Gene Ontology terms and nine significant Kyoto Encyclopedia of Genes and Genomes (KEGG) pathways were identified, most of which were correlated with disease resistance and biosynthesis processes, and one KEGG pathway was related to lipid metabolism. …”
Publicado 2021
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20445por Gu, Chang, Chen, Jiafei, Dang, Xuening, Chen, Chunji, Huang, Zhenyu, Shen, Weidong, Shi, Xin, Dai, Chenyang, Chen, Chang“…Differential expression genes (DEGs) and Gene Ontology (GO), Kyoto Encyclopedia of Genes and Genomes (KEGG) analyses were explored. …”
Publicado 2021
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20446“…We constructed a co-expression network of chimeric genes in pigs and conducted Gene Ontology enrichment and Kyoto Encyclopedia of Genes and Genomes pathway analysis on the generated modules using DAVID to identify key networks and modules related to chimeric genes. …”
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20447por Luan, Jiao-chen, Zhang, Qi-jie, Zhao, Kai, zhou, Xiang, Yao, Liang-yu, Zhang, Tong-tong, Zeng, Teng-yue, Xia, Jia-dong, Song, Ning-hong“…Kaplan-Meier (KM) survival analysis, time-dependent receiver operating curve (ROC), independent prognostic analysis and nomogram were also applied to evaluate the prognostic value of the signature. Besides, Gene ontology analysis (GO), Kyoto encyclopedia of genes and genomes (KEGG) and gene set enrichment analysis (GSEA) were used to explore potential biological pathways. …”
Publicado 2021
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20448por Huang, Jian-Lv, Wang, Xiang-Kun, Liao, Xi-Wen, Han, Chuang-Ye, Yu, Ting-Dong, Huang, Ke-Tuan, Yang, Cheng-Kun, Liu, Xiao-Guang, Yu, Long, Zhu, Guang-Zhi, Su, Hao, Qin, Wei, Han, Quan-Fa, Liu, Zheng-Qian, Zhou, Xin, Liu, Jun-Qi, Ye, Xin-Ping, Peng, Tao“…Gene set enrichment analysis was explored as well as candidate gene ontology and metabolic pathways modulated by in SOX4 HCC. …”
Publicado 2021
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20449“…The results of Gene Ontology and KEGG pathway analysis revealed that these miRNAs were mainly involved in certain biological functions, such as metabolic processes, such as galactose metabolism and signaling pathways (PI3K-AKT) associated with COPD. …”
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20450por Li, Lin, Zhou, Donghai, Liu, Qiuping, Li, Dianming, Wang, Qiao, Shi, Xiaowei, Wen, Chengping, Huang, Lin“…Microarray of 20 early untreated RA patients and corresponding health control were download from NCBI Gene Expression Omnibus (GEO) database to defined the differential expressed genes. Gene ontology analysis and KEGG enrichment analysis were carried out for the YQCP. …”
Publicado 2021
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20451“…METHODS: RNA-sequencing (RNA-seq) was conducted with and without TQ treatment in TNBC cell line BT-549. Gene Ontology (GO) function classification annotation, Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analyses for these genes were conducted. …”
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20452por Hao, Shengyu, Jiang, Pan, Xie, Liang, Xiang, Guiling, Liu, Zilong, Hu, Weiping, Wu, Qinhan, Jiang, Liyan, Xiao, Yi, Li, Shanqun“…Methods: In our research, we utilized the robust rank aggregation (RRA) method to integrate four eligible pulmonary arterial hypertension (PAH) microarray datasets and identified the significant differentially expressed genes (DEGs) between IPAH and normal samples. Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathways were performed to analyze their functions. …”
Publicado 2021
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20453“…A quantitative approach including tandem mass tag labeling and liquid chromatography tandem mass spectrometry (TMT) was employed to identify differentially expressed proteins. Gene Ontology (GO) and the Kyoto Encyclopedia of Genes and Genomes (KEGG) analyses were then conducted to interrogate the functions and pathways of identified proteins. …”
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20454“…The MuTaME method was used to predict the ceRNA regulatory network. Gene ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) analyses were performed using the DAVID database. …”
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20455“…DIANE interactive workflow provides normalization, dimensionality reduction, differential expression and ontology enrichment. Gene clustering can be performed and explored via configurable Mixture Models, and Random Forests are used to infer gene regulatory networks. …”
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20456por Zhou, Le-Ting, Zhang, Zhi-Jian, Cao, Jing-Yuan, Chen, Hanzhi, Zhu, Yu-Shan, Wu, Xi, Nawabi, Abdul Qadir, Liu, Xiaobin, Shan, Weiwei, Zhang, Yue, Zhang, Xi-Ran, Xue, Jing, Hu, Ling, Wang, Si-Si, Wang, Liang, Sun, Zhu-Xing“…Based on these DEG sets, the unique DEGs of DN were identified and further analyzed using gene ontology and pathway enrichment analysis. Finally, the protein–protein interaction networks (PINs) were constructed and hub genes were selected to further refine the results. …”
Publicado 2021
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20457“…The association between CD24 expression and immune response was conducted using Cell-type Identification By Estimating Relative Subsets Of RNA Transcripts (CIBERSORT) methodology and Gene Ontology (GO) biological process (BP) analysis. RESULTS: The positive expression rate of CD24 mRNA in ABC-DLBCL patients was 38.1% (45/118). …”
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20458por Fang, Hongcheng, Liu, Xia, Dong, Yuhui, Feng, Shan, Zhou, Rui, Wang, Changxi, Ma, Xinmei, Liu, Jianning, Yang, Ke Qiang“…Using pairwise comparisons and weighted gene co-expression network analysis of the transcriptome, we identified two modules significantly related to disease resistance and nine hub genes in the transcription expression gene networks. Gene Ontology and Kyoto Encyclopedia of Genes and Genomes analysis of the DEGs and DEPs revealed that many genes were mainly related to immune response, plant hormone signal transduction, and secondary metabolites, and many DEPs were involved in carbon metabolism and photosynthesis. …”
Publicado 2021
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20459“…In addition, we performed the Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment by the Annotation, Visualization, and Integrated Discovery database. …”
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20460“…VI, we identified 1,059 DE mRNAs and 187 DE lncRNAs. Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) enrichment analyses showed that DE mRNAs were enriched in ECM-receptor interaction, oocyte meiosis and steroid hormone biosynthesis pathways. …”
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