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20761por Xiao, Yao, Zhang, Baoluhe, Cloyd, Jordan M., Alaimo, Laura, Xu, Gang, Du, Shunda, Mao, Yilei, Pawlik, Timothy M.“…Function annotation and enrichment pathway analyses of the differentially expressed genes (DEGs) were finished using the Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) databases. …”
Publicado 2022
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20762“…The related functions of IRDEGs were analyzed through Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG). …”
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20763“…Differentially expressed genes (DEGs) were screened by R software and limma packages. Gene Ontology (GO) functional enrichment analysis and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment analysis were performed on DEGs by public databases. …”
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20764por Guo, Shuai, Zhang, Erli, Zhang, Bin, Liu, Qingrong, Meng, Zhen, Li, Ziang, Wang, Can, Gong, Zhaoting, Wu, Yongjian“…A protein-protein-interaction (PPI) network of DEGs was then constructed using the Search Tool for the Retrieval of Interacting Genes/Proteins database, and functional modules were analyzed with ClusterOne plugin in Cytoscape. Furthermore, Gene Ontology-functional annotation and Kyoto Encyclopedia of Genes and Genomes-pathway analysis were conducted for each functional module. …”
Publicado 2022
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20765por Qin, Ping, Ye, Jing, Gong, Xinbao, Yan, Xu, Lin, Maosen, Lin, Tao, Liu, Tong, Li, Hailing, Wang, Xiujuan, Zhu, Yanyun, Li, Xiaoqian, Liu, Ya, Li, Yunsheng, Ling, Yinghui, Zhang, Xiaorong, Fang, Fugui“…Kyoto Encyclopedia of Genes and Genomes pathway enrichment analysis indicated that DAPs were enriched in olfactory transduction, glutathione metabolism, and calcium signaling pathways. Besides, gene ontology functional enrichment analysis revealed that several DAPs enriched in biological processes were associated with cellular process, biological regulation, metabolic process, and response to stimulus. …”
Publicado 2022
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20766por Huang, Zhengnan, Yan, Yilin, Wang, Tengjiao, Wang, Zeyi, Cai, Jinming, Cao, Xiangqian, Yang, Chenkai, Zhang, Fang, Wu, Gang, Shen, Bing“…Kaplan–Meier analysis, ROC curve, univariate and multivariate Cox regression were performed to evaluate the predictive capability of the ENO1. Gene ontology (GO) and Gene Set Enrichment Analyses (GSEA) analysis were employed to perform the biological processes enrichment. …”
Publicado 2022
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20767“…For acquisition of gene functions and biological pathways they involved in, gene ontology (GO) and Kyoto encyclopedia of genes and genomes (KEGG) enrichment analyses were performed, and several DEGs were found to possibly participate in the tannins biosynthesis pathway and transport processes of precursors. …”
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20768por Aass, Kristin Roseth, Nedal, Tonje Marie Vikene, Tryggestad, Synne Stokke, Haukås, Einar, Slørdahl, Tobias S., Waage, Anders, Standal, Therese, Mjelle, Robin“…We found that miRNA-mRNA pairs that were predicted by in silico target-prediction algorithms were more negatively correlated than non-target pairs, indicating functional miRNA targeting and that correlation between miRNAs and mRNAs from patients can be used to identify miRNA-targets. mRNAs for negatively correlated miRNA-mRNA target pairs were associated with gene ontology terms such as autophagy, protein degradation and endoplasmic stress response, reflecting important processes in MM. …”
Publicado 2022
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20769por Lang, Wanying, Yang, Feng, Cai, Fanfan, Shi, Wengui, Dong, Min, An, Qi, Li, Yanping“…The critical targets of YFJPT are explored by Gene Ontology (GO) and the Kyoto Encyclopedia of Genes and Genomes (KEGG). …”
Publicado 2022
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20770por Wang, Hongxian, Shu, Lirong, Niu, Nan, Zhao, Chenyang, Lu, Shuqi, Li, Yanhua, Wang, Huanyu, Liu, Yao, Zou, Tianhui, Zou, Jiawei, Wu, Xiaoqin, Wang, Yun“…The expressive profiles and associated downstream-mRNAs were assessed using bioinformatics (such as weighted correlation network analysis (WGCNA), Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genome (KEGG) enrichments, Receiver-Operating Characteristic (ROC) curve and survival analysis, etc.) to investigate the diagnostic and prognostic values of these EV lncRNAs and their effectors. …”
Publicado 2022
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20771por Guo, Xuan, Wang, Ziying, Deng, Xue, Lu, Yantong, Huang, Xuhui, Lin, Juze, Lan, Xiaohe, Su, Qiao, Wang, Changjun“…Through biological website to predict the target genes of miR-184 may be combined. Gene ontology (GO), Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analysis were performed to investigate mRNAs with significant functional enrichment and pathways, also which its relationship with HCC-related pathway and immune cells. …”
Publicado 2022
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20772por Song, Dandan, He, Huan, Indukuri, Rajitha, Huang, Zhiqiang, Stepanauskaite, Lina, Sinha, Indranil, Haldosén, Lars-Arne, Zhao, Chunyan, Williams, Cecilia“…RNA sequencing revealed that E2 regulated a transcriptome of around 800 genes via each receptor, but over half were specific for either ERα or ERβ (417 and 503 genes, respectively). Functional gene ontology enrichment analysis reinforced that E2 regulated cell proliferation in opposite directions depending on the ER, and that ERβ specifically impacted extracellular matrix organization. …”
Publicado 2022
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20773“…The least absolute shrinkage and selection operator (LASSO) regression was performed to identify the independent prognostic signatures. Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) analyses were conducted to explore the functional enrichment of selected genes, and gene set enrichment analysis of cuproptosis-related genes was completed. …”
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20774por Luo, Haixin, Xie, Bo, Xu, Jinhui, Zhu, Yuqi, Sun, Jiayi, Shen, Yuqing, Song, Xiuzu“…Different databases were used to predict gene targets of miRNAs, which were analyzed by gene ontology and Kyoto encyclopedia of genes and genomes (KEGG). …”
Publicado 2022
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20775por Yuan, Hao, Zhang, Xiu-Xiang, Yang, Zi-Peng, Wang, Xiao-Hu, Mahmmod, Yasser S., Zhang, Pian, Yan, Zi-Jing, Wang, Yan-Yun, Ren, Zhao-Wen, Guo, Qing-Yong, Yuan, Zi-Guo“…DEGs were mainly enriched in cellular process and metabolic process based on gene ontology enrichment analysis. Kyoto Encyclopedia of Genes and Genomes pathway analysis showed that transcriptional changes in the brain of infected masked palm civets evolved over the course of infection and that DEGs were mainly enriched in the signal transduction, immune system processes, transport and catabolic pathways. …”
Publicado 2022
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20776por Zhou, Xuan, Cong, Rong, Yao, Liangyu, Zhou, Xiang, Luan, Jiaochen, Zhang, Qijie, Zhang, Xu, Ren, Xiaohan, Zhang, Tongtong, Meng, Xianghu, Song, Ninghong“…The construction of the lncRNA-miRNA-mRNA network, the Gene Ontology (GO) term enrichment, and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analysis were performed in Cytoscape. …”
Publicado 2022
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20777por Ye, Shaopan, Yu, Xiaoyan, Chen, Huiying, Zhang, Yin, Wu, Qingyang, Tan, Huaqiang, Song, Jun, Saqib, Hafiz Sohaib Ahmed, Farhadi, Ardavan, Ikhwanuddin, Mhd, Ma, Hongyu“…In addition, the top ten significant gene ontology (GO) terms were related to the cuticle or chitin. …”
Publicado 2022
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20778por Wang, Wenjuan, Ye, Yingquan, Zhang, Xuede, Ye, Xiaojuan, Liu, Chaohui, Bao, Lingling“…The models were also validated and evaluated by Kaplan-Meier analysis, univariate and multivariate Cox regression, and time-dependent receiver operating characteristic (ROC) curves. In addition, Gene Ontology, Kyoto Encyclopedia of Genes and Genomes enrichment, gene set enrichment, principal component, immune correlation, and drug sensitivity analyses were applied to assess model risk groups. …”
Publicado 2022
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20779por Wang, Chenxing, Aikemu, Batuer, Shao, Yanfei, Zhang, Sen, Yang, Guang, Hong, Hiju, Huang, Ling, Jia, Hongtao, Yang, Xiao, Zheng, Minhua, Sun, Jing, Li, Jianwen“…Signaling pathways related to MTOR in CRC were identified by Gene Ontology (GO), Kyoto Encyclopedia of Genes and Genomes (KEGG), and gene set enrichment analysis (GSEA). …”
Publicado 2022
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20780“…The DEGs between normal and DN renal tissues were performed using the Linear Models for Microarray (limma) package. Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment analyses were performed to reveal the mechanisms of DEGs in the progression of DN. …”
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