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  1. 21041
    “…Furthermore, RNA-Seq analyses identified different expressed genes (DEGs) in PAX1 overexpressed SiHa cells. Gene Ontology (GO) and pathway enrichment analysis was carried out to determine the biological function of DEGs. …”
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    PAX1 hypomethylation as a prognostic biomarker for radioresistance of cervical cancer
  2. 21042
    “…Differentially expressed (DE) genes between experimental groups were characterized based on RNA-seq and Gene Ontology (GO) enrichment analyses. RESULTS: The overall gene expression pattern was very similar between untreated PR-low and untreated control T-47D cells. …”
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    Molecular characterization of breast cancer cell pools with normal or reduced ability to respond to progesterone: a study based on RNA-seq
  3. 21043
    “…Protein–protein interaction (PPI) network analysis and visualization were carried out with STRING and Cytoscape, and key CD ferroptosis-related genes (CD-FRGs) were identified along with their Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathways using the clusterProfiler package. …”
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    Exploration of key ferroptosis-related genes and immune infiltration in Crohn’s disease using bioinformatics
  4. 21044
    por Cheng, Hongxia, Liu, Yuhua, Chen, Gang
    Publicado 2023
    “…Aberrantly expressed genes were obtained by GEO2R. Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathways were analyzed using the DAVID database and KOBAS. …”
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    Identification of potential DNA methylation biomarkers related to diagnosis in patients with bladder cancer through integrated bioinformatic analysis
  5. 21045
    “…RESULTS: A total of 16,370 differentially expressed genes were obtained across different vernalization periods. Gene Ontology enrichment analysis revealed that photoperiodism, photoprotection, photosynthesis, lipid transport and biosynthetic process, and chlorophyll metabolic process were closely related to vernalization. …”
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    Transcriptome analysis during vernalization in wheat (Triticum aestivum L.)
  6. 21046
    “…Gene set enrichment analysis (GSEA), Gene Ontology (GO), and the Kyoto Encyclopedia of Genes and Genomes (KEGG) analysis were used for biological process enrichment. …”
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    Tetraspanins predict the prognosis and characterize the tumor immune microenvironment of glioblastoma
  7. 21047
    por Calabrò, M., Crisafulli, C., Drago, A.
    Publicado 2023
    “…Performance was evaluated through 5-fold cross-validation, Python, R and Bash served for environments. Gene Ontology, ReactomePA and Bioconductor were key packages together with Cytoscape, Plink, impute and gtool. …”
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    Genetic underpinnings of YMRS and MADRS scores variations in a bipolar sample
  8. 21048
    por Amiri, Maryam, Li, Juan, Hasan, Wordh
    Publicado 2023
    “…Specifically, we constructed an ontology-based knowledge base to model knowledge about food and nutrition. …”
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    Personalized Flexible Meal Planning for Individuals With Diet-Related Health Concerns: System Design and Feasibility Validation Study
  9. 21049
    “…These DEGs were subjected to Gene Ontology (GO) term analyses that indicated they were enriched in the ‘fatty acid metabolism’, ‘response to stress’, ‘carbon fixation’ and ‘photosynthesis’ functional categories, in line with the ND treatment conditions used to conduct this study. …”
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    Remodeling of the 3D chromatin architecture in the marine microalga Nannochloropsis oceanica during lipid accumulation
  10. 21050
    “…Differentially expressed genes (DEGs) were screened and then subjected to Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) functional correlation analysis, as well as protein-protein interaction (PPI) network analysis. …”
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    Identifying immune cell infiltration and effective diagnostic biomarkers in Crohn’s disease by bioinformatics analysis
  11. 21051
    “…The down-regulated genes of this enzyme were found to be enriched in the cell cycle, DNA replication, mitotic processes, and the oxidative phosphorylation pathway, as previously revealed from gene ontology (GO), Kyoto encyclopedia of genes and genomes (KEGG), and gene set enrichment analysis (GSEA), suggesting vital roles of the Kdm4d enzyme in the cell cycle and in antioxidant regulation. …”
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    Lysine-Specific Demethylase 4D Is Critical for the Regulation of the Cell Cycle and Antioxidant Capacity in Goat Fibroblast Cells
  12. 21052
    “…In total, 34 circRNAs, 57 lncRNAs, 15 miRNAs, and 374 mRNAs were identified by integrating gene ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) enrichment analyses. …”
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    Integrated Comparative Transcriptome and circRNA-lncRNA-miRNA-mRNA ceRNA Regulatory Network Analyses Identify Molecular Mechanisms Associated with Intramuscular Fat Content in Beef Cattle
  13. 21053
    “…These networks were further analyzed using gene ontology (GO) and Kyoto encyclopedia of genes and genomes (KEGG). …”
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    Duhuo Jisheng decoction alleviates neuroinflammation and neuropathic pain by suppressing microglial M1 polarization: a network pharmacology research
  14. 21054
    “…To determine the potential signaling pathway of lncRNA Gm2044 regulating estradiol synthesis, transcriptome sequencing was performed for ovaries of adult lncRNA Gm2044 knockout mice, which identified 565 significant up-regulated genes and 303 significant down-regulated genes, which were then analyzed with Gene Ontology (GO) and the Kyoto Encyclopedia of Genes and Genomes (KEGG) and validated by molecular experiments. …”
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    Interaction of lncRNA Gm2044 and EEF2 promotes estradiol synthesis in ovarian follicular granulosa cells
  15. 21055
    “…Furthermore, strongly co-expressed genes in modules, which were named by color, were clustered by Weighted gene co-expression network analysis (WGCNA) based on dynamic tree cutting algorithm. Gene ontology (GO) and kyoto encyclopedia of genes and genomes (KEGG) enrichment were subsequently implemented, and hub genes were described in each module. …”
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    Identification of crucial modules and genes associated with backfat tissue development by WGCNA in Ningxiang pigs
  16. 21056
    “…Bioinformatic analyses, including gene ontology (GO) and KEGG pathway analysis, were performed using R. …”
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    DNA methylation patterns in CD4(+) T-cells separate psoriasis patients from healthy controls, and skin psoriasis from psoriatic arthritis
  17. 21057
    “…GSE12470, GSE14407 and GSE54388 were downloaded from the Gene Expression Omnibus (GEO) database, and GEO2R was used to screen differentially expressed genes in ovarian cancer tissues. Gene Ontology (GO) enrichment analysis was used to explore the related biological processes. …”
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    The role of OIP5 in the carcinogenesis and progression of ovarian cancer
  18. 21058
    “…Molecular signatures of these genes were analysed using gene ontology. RNA-seq analyses identified 74 upregulated and 320 downregulated genes involved in cell motility, cytokine production, and kinase activity. …”
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    FUS-ERG induces late-onset azacitidine resistance in acute myeloid leukaemia cells
  19. 21059
    “…Alterations in differentially expressed proteins were determined using sequential window acquisition of all theoretical fragment ion mass spectroscopy (SWATH-MS)-based quantitative proteomics, and Metascape, STRING, Gene Ontology, and KEGG were used for network analyses of altered biological pathways and processes. …”
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    Proteomic alterations in the brain and blood–brain barrier during brain Aβ accumulation in an APP knock-in mouse model of Alzheimer’s disease
  20. 21060
    por Yuan, Qian, Zhang, Haiqiao
    Publicado 2023
    “…In addition, DEGs analysis was performed by Gene Ontology (GO) functional analysis and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analysis. …”
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    Identification of differentially expressed genes and pathways in BEAS-2B cells upon long-term exposure to particulate matter (PM(2.5)) from biomass combustion using bioinformatics analysis
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